Hans Senn

Hans Senn is a Lecturer in Theoretical & Computational Chemistry at the School of Chemistry, University of Glasgow. His research focuses on computational approaches to chemical reactions, particularly through combined quantum mechanics/molecular mechanics (QM/MM) methods. He leads a research group dedicated to understanding enzymatic reactions, transition-metal chemistry, and catalytic systems through advanced computational techniques.

His research interests encompass computational studies of enzymatic reactions using QM/MM, computational transition-metal and organometallic chemistry including homogeneous catalysis, first-principles and QM/MM molecular dynamics, sampling techniques and free-energy calculations, and modeling of solvation effects. His work bridges theoretical chemistry with practical applications in biochemistry and materials science, with recent publications showing increased interdisciplinary collaboration across physical chemistry, biochemistry, and materials science domains.

His recent publication trend reveals a strong focus on multiscale modeling approaches, with significant contributions to understanding enzymatic mechanisms, molecular vibrations in complex systems, and the development of computational tools for spectroscopic prediction. His work spans both fundamental theoretical developments and applications to biological and materials systems.

• Dr sc nat (ETH Zurich)
• MRSC

As an educator, Senn serves as Head of Chemistry-1 and teaches advanced courses including Symmetry and Bonding (Chem-3) and Theoretical and Computational Chemistry (Chem-4). His research group actively collaborates across disciplines, with recent work involving teams in biophysics, materials science, and medicinal chemistry. He has presented at major conferences including Gordon Research Conferences and ACS National Meetings, demonstrating his active engagement with the international computational chemistry community.