Sampreeti Jena

Sampreeti Jena is a Researcher in the Department of Experimental and Clinical Pharmacology at the University of Minnesota. Her work focuses on cancer pharmacology, enzyme activity imaging, and computational drug discovery, particularly for castration-resistant prostate cancer and pediatric central nervous system tumors.

• Institution: University of Minnesota
• Department: Experimental and Clinical Pharmacology

Her research interests include:

• Using single-cell transcriptomics and pan-cancer analysis to identify therapeutic vulnerabilities in heterogeneous tumors
• Developing fluorescence lifetime imaging (FLIM) probes for kinase activity measurement
• Investigating protein stability in pharmaceutical formulations
• Creating computational models for drug response prediction

Recent publications highlight her contributions to precision oncology through:

• Digital tumor modeling for therapeutic inference
• Identification of pan-histology immunomodulatory targets
• Advancements in FLIM probe technology
• Excipient interaction studies affecting protein stability

Current projects include:

• Dynamic Digital Tumors for Precision Oncology (University of California San Diego, 2024-2025)
• Genetic mechanisms underlying sexual dimorphism in cancer (University of Colorado & NIH, 2024-2026)