جستجوی استاد راهنمای دانشگاهی

• Cell Biology
• Molecular Biology
• DNA-Protein Interactions
• +۳ مورد دیگر

Zhiqun Xi is an Associate Research Scientist in the Department of Cell Biology at Yale University's School of Medicine. He holds a PhD from the University of Hong Kong (2000). His research focuses on molecular mechanisms of DNA-protein interactions, cell signaling pathways, and biophysical techniques. Key areas include p53-mediated transcriptional regulation, EGF pathway dynamics, and super-resolution microscopy. Collaborations with experts like Yongli Zhang and Anthony Koleske highlight interdisciplinary work in cellular and molecular biology. Publications span studies on exocyst-mediated exocytosis, p53/DNA binding modes, and neuronal SNARE complex dynamics. His work integrates optical tweezers, STED nanoscopy, and single-molecule fluorescence microscopy to explore molecular processes at high resolution. Research contributions address fundamental questions in cell biology and cancer biology, with implications for understanding cellular signaling and disease mechanisms. Xi’s research has been published in journals like *Proceedings of the National Academy of Sciences*, *Science*, and *Biophysical Journal*. While no specific awards or grants are listed, his consistent output reflects sustained contributions to molecular and cellular research.

Ning Wangمشاهده پروفایل

استادیار

• Cell Biology
• Biochemistry
• Molecular Genetics
• +۷ مورد دیگر

Ning Wang is an Assistant Professor in the Department of Biology at the University of Rochester. Her research focuses on organelle homeostasis through biogenesis and degradation mechanisms, with affiliations to the Biochemistry and Molecular Biology Program and Biomedical Genetics and Genomics Program. PhD in Molecular Genetics, Ohio State University Postdoctoral training in Cell Biology, Harvard Medical School Dr. Wang's research explores: Organelle biogenesis, particularly the endoplasmic reticulum (ER), including morphology generation, inheritance during cell division, and protein/lipid insertion. Organelle degradation via receptor-mediated selective autophagy, linking dysfunction to neurodegeneration, cancer, and metabolic disorders. Asymmetric organelle inheritance in Schizosaccharomyces japonicus hyphae. Research trends from publications include: 2023 study on autophagosome formation in fission yeast 2021 work on ER tubule shaping proteins 2019 analysis of ER network reconstitution 2014-2016 investigations of cytokinesis mechanisms in yeast Her lab employs fission yeast (Schizosaccharomyces pombe/japonicus), budding yeast (Saccharomyces cerevisiae), and mammalian cell cultures for genetic studies, combined with protein purification and structural biology techniques.

Mary Munsonمشاهده پروفایل

استاد

• Vesicle Targeting and Fusion
• Membrane Trafficking
• Exocyst Complex
• +۳ مورد دیگر

Mary Munson is a Professor at UMass Chan Medical School, Department of Biochemistry and Molecular Biotechnology. She holds multiple affiliations including the T.H. Chan School of Medicine, Morningside Graduate School of Biomedical Sciences, and the NeuroNexus Institute. Her academic journey includes a B.A. in Chemistry & Biology from Washington University (1989) and a Ph.D. in Molecular Biophysics & Biochemistry from Yale University (1996). She completed postdoctoral research at Princeton University, focusing on molecular biology, before joining UMass Chan in 2001. Her research investigates the regulation of vesicle targeting and fusion in eukaryotic cells, particularly using the yeast Saccharomyces cerevisiae as a model. Key areas include the structural and functional analysis of the Exocyst complex, SNARE protein interactions, and membrane fusion mechanisms. Techniques employed span biochemical assays, structural biology (e.g., X-ray crystallography), yeast genetics, and microscopy. Current projects include understanding Exocyst architecture, identifying novel regulators of exocytosis, and characterizing the role of Vps45p in endosomal SNARE assembly. Her publications highlight interdisciplinary approaches to membrane trafficking, with contributions to understanding exocyst-SNARE interactions, Rab protein functions, and the structural dynamics of protein complexes. Despite no explicitly listed awards, her work frequently appears in high-impact journals like Nature Structural & Molecular Biology and Molecular Biology of the Cell . She mentors graduate students through programs in Biophysical Chemical and Computational Biology, Immunology, and Neuroscience. Lab activities include cloning and protein purification studies, structural analysis of Exocyst domains, and genetic screens to identify new regulators. Future directions aim to bridge yeast findings to human cellular processes, with implications for neurological disorders and genetic diseases linked to exocyst dysfunction.

Sarris Panagiotisمشاهده پروفایل

دانشیار

• Molecular Microbiology
• Molecular Pathogen-Host Interactions
• Microbiomes analysis
• +۴ مورد دیگر

Sarris Panagiotis is an Associate Professor in the Department of Biotechnology and Applied Biology at the University of Crete, where he conducts research at the intersection of plant-microbe interactions and molecular immunology. His work focuses on understanding the molecular mechanisms underlying plant immune responses to bacterial pathogens, with particular emphasis on effector-triggered immunity and host-pathogen coevolution. His primary research interests include Molecular Microbiology, Molecular Pathogen-Host Interactions, Microbiomes analysis, Molecular Immunology of plant organisms, Molecular bacteriology, and Plants and microbes genomic sequencing annotation and analysis. His laboratory investigates how plant immune receptors recognize pathogen effectors and how these interactions shape plant defense responses. Dr. Sarris's publication record demonstrates a strong focus on plant immune receptor architecture, particularly NLR (Nucleotide-binding Leucine-rich Repeat) receptors, and their role in recognizing bacterial effectors. His work spans structural biology, molecular genetics, and functional genomics approaches to dissect plant-pathogen interactions. Recent publications highlight his contributions to understanding how bacterial effectors target host cellular machinery and how plants have evolved countermeasures to detect these virulence strategies. His research has significant implications for developing novel strategies for crop protection against bacterial diseases. The laboratory employs a multidisciplinary approach combining molecular biology, biochemistry, genetics, and advanced imaging techniques to investigate plant immune mechanisms.

Ying Guمشاهده پروفایل

استاد

• Cellulose Biosynthesis
• Plant Cell Wall Biology
• Microtubule Dynamics
• +۳ مورد دیگر

Ying Gu is a Professor in the Department of Biochemistry & Molecular Biology at Pennsylvania State University. Her research focuses on cellulose biosynthesis in plants, particularly the identification and characterization of novel components in cellulose synthase complexes to enhance biomass-based energy production. She is affiliated with the Institute of Energy and the Environment (IEE) under the theme of Integrated Energy Systems. Her work integrates molecular genetics, cell biology, and biophysical techniques to understand plant cell wall architecture and its implications for bioenergy applications. Key research interests include the regulation of cellulose synthase complexes, microtubule dynamics, and the interplay between plant cell walls and energy production. Dr. Gu’s lab develops innovative tools like the Dot Scanner software for live-cell imaging, advancing quantitative analysis of plant cell processes. Her recent publications highlight discoveries in cellulose synthase trafficking mechanisms, the role of calcium-dependent protein kinases, and the structural properties of plant cell walls. Collaborations with institutions like the Center for Quantitative Imaging and Radiocarbon Laboratory at Penn State support interdisciplinary approaches to plant biology challenges. Dr. Gu has been recognized for research excellence, including awards from the IEE. Her work bridges fundamental plant biology with applied bioenergy research, contributing to sustainable biomass utilization strategies.

John Fowler Jrمشاهده پروفایل

استاد

• Plant Cell Biology
• Developmental Biology
• Genomics
• +۵ مورد دیگر

John Fowler Jr. is a Professor in the Department of Botany and Plant Pathology at Oregon State University, affiliated with the College of Agricultural Sciences. His research focuses on plant cell and developmental biology, particularly the molecular mechanisms governing cellular morphogenesis and development in plants, with a focus on cell polarity and exocytosis. He holds leadership roles, including Associate Head of his department and contributions to curriculum development. Education: Ph.D. in Genetics (UC Berkeley, 1994), B.S. in Genetics (University of Georgia, 1987). Research Interests: Plant cell polarity, exocytosis, pollen development, maize and Arabidopsis models, systems biology approaches, and genome-driven research. His work integrates genetics, cell biology, and 'omics-scale methods. Recent projects include high-throughput phenotyping of maize kernels and investigating exocyst complex functions. He has advised numerous graduate and undergraduate students, contributing to over 50 publications. Awards include the Loyd Carter Award for Excellence in Teaching (2003) and NSF fellowships. Service includes leadership in professional organizations, such as the Maize Genetics Conference, and public outreach on GMOs. His grants total over $6.7 million, with funding from NSF, USDA-NIFA, and EPA.

Hannes Maibمشاهده پروفایل

پژوهشگر ارشد

• Membrane Biology
• Phosphoinositide Signaling
• Organelle Communication
• +۳ مورد دیگر

Dr. Hannes Maib is a Wellcome Trust Early Career Fellow at the School of Biosciences, University of Sheffield. His research focuses on membrane identity regulation and its role in cellular processes, particularly membrane contact site formation. He holds a PhD from the University of Sheffield (2015-2019) and completed postdoctoral work at the University of Dundee (2019-2023). Education: BSc in Molecular Biomedicine, University of Bonn (2010-2013) MSc in Life and Medical Sciences, University of Bonn (2013-2015) PhD in Cell Biology, University of Sheffield (2015-2019) Research Interests: Membrane identity changes, phosphoinositide signaling, organelle communication via contact sites, lipid transport defects in disease. His lab combines advanced imaging and biochemical reconstitution techniques to study these mechanisms. Awards: Wellcome Trust Early Career Fellowship (2023-Present) Grants & Advising: Led independent research since 2023 Advising PhD student Ben Allouis and postdoc Lewis Hancock Labs/Teams: Maib Lab focuses on integrating imaging and biochemical approaches to uncover molecular mechanisms of membrane identity regulation.

Assaad Gerbert Farhahمشاهده پروفایل

استاد

• Plant resilience to climate stress
• Agroforestry systems
• Membrane trafficking in plants
• +۳ مورد دیگر

Prof. Assaad Gerbert Farhah is a Professor in the TUM School of Life Sciences at the Technical University of Munich, leading the Biotechnology of Natural Products group under Prof. Wilfried Schwab. His research focuses on plant resilience to climate stresses like heat, drought, and low light, spanning from ecosystem-level agroforestry systems to molecular mechanisms of growth decisions. He holds a PhD from MIT and has held key roles at institutions including the Carnegie Institution at Stanford and LMU Munich. Education: PhD in Biology, MIT, 1992 MSc in Biology, University of Geneva, 1986 International Baccalaureate, International School of Geneva, 1981 Research Interests: Plant stress adaptation at genetic/molecular levels Agroforestry scalability and soil regeneration TRAPP complex signaling and Rab GTPase interactions Grants/Projects: DFG AS110/8-1 (Decision-making in Arabidopsis) Horizon 2020-funded BSLchlamy project TUMmesa ecotron climate simulations Labs/Teams: Collaborations with Carnegie Institution, Finck Stiftung, and TUM Venture Labs for climate mitigation tech integration.

Gulcin Pekkurnazمشاهده پروفایل

دانشیار

• Neurobiology
• Mitochondrial Biology
• Neuronal Metabolism
• +۳ مورد دیگر

Gulcin Pekkurnaz is an Associate Professor in the Department of Neurobiology at the University of California San Diego (UCSD). Her research focuses on understanding how mitochondrial function is coupled with neuronal metabolism, particularly in the context of neurological diseases. Her lab employs interdisciplinary approaches including molecular biology, mouse genetics, metabolic flux analysis, and advanced imaging techniques like super-resolution microscopy. Key research interests include mitochondrial dynamics, energy homeostasis at synapses, and the role of mitochondria in neurodegenerative diseases. She investigates how metabolic requirements vary across neuronal subtypes and how mitochondrial dysfunction contributes to disease pathogenesis. Her work integrates systems biology modeling with experimental methods to study mitochondria-endoplasmic reticulum contact sites and calcium signaling. Her lab utilizes cutting-edge tools such as deep learning-based super-resolution imaging and computational modeling to unravel novel metabolic pathways. Current projects explore O-GlcNAcylation's role in mitochondrial plasticity, glycolytic metabolon assembly, and glucose-dependent mitochondrial trafficking mechanisms. Contact: gpekkurnaz@ucsd.edu

• Plant Pathology
• Exocytosis
• Phytophthora infestans
• +۷ مورد دیگر

Elysa Overdijk is a Lecturer at the Laboratory of Plant Physiology , Wageningen University. Her work bridges plant pathology , cell biology , and molecular imaging to uncover defense mechanisms against pathogens. PhD in Plant Physiology (2019) from Wageningen University Current role: Lecturer in plant physiology teaching Overdijk's research examines exocytosis and microtubule dynamics during plant-pathogen interactions, with a focus on Phytophthora infestans and Physcomitrium patens models. Her work integrates confocal microscopy and exocyst complex analysis to visualize cellular responses. Key publication trends include: Investigating RXLR effectors and their impact on plant growth Mapping exocyst subunit localization during infection Elucidating microtubule overlaps in phragmoplast function Exploring small RNA mechanisms in disease resistance She collaborates with experts like Prof. Francine Govers and Dr. K. Bouwmeester in projects such as " The plant exocyst as an expeller of pathogens " (2014-2019). Her methodological toolkit spans time-gated microscopy , RNA interference studies , and cytoskeleton analysis .

• Adult Stem Cell
• Cancer Immunology
• Wound Healing
• +۱ مورد دیگر

Yuxuan (Phoenix) Miao is an Assistant Professor at the University of Chicago in the Ben May Department of Cancer Research . Their research focuses on the interaction between epithelial stem cells and the immune system in tissue repair and cancer immune evasion. PhD in Immunology from Duke University School of Medicine (2015) Postdoctoral training in Stem Cell and Cancer Biology at Rockefeller University (2020) Research interests include: Adult Stem Cell Biology - studying how stem cells adapt to inflammation Cancer Immunology - mechanisms of immune evasion in tumors Tissue Regeneration - inflammatory repair processes in epithelial tissues Key awards: NCI K99/R00 Pathway to Independence Award Jane Coffin Childs Fellowship Duke Chancellor Award Current grants include NIH R01CA285786 and R35GM150610 supporting studies on: Stem cell transcriptional networks in tumor immunity Inflammatory adaptation mechanisms in epithelial cancers The Miao Lab at the University of Chicago Comprehensive Cancer Center integrates these findings to develop novel immunotherapies for cancer and regenerative medicine.

Bing Heمشاهده پروفایل

دانشیار

• Cell biology
• Developmental biology
• Biophysics
• +۳ مورد دیگر

Bing He is an Associate Professor in the Department of Biological Sciences at Dartmouth College, with joint affiliations in the Molecular and Cellular Biology Graduate Program and the Cancer Biology and Developmental Therapeutics Research Program at the Norris Cotton Cancer Center. His research employs interdisciplinary approaches to investigate mechanical aspects of tissue morphogenesis during embryonic development. He holds a B.S. from Peking University and a Ph.D. from the University of Pennsylvania, specializing in mechanisms of cellular organization and developmental dynamics. His laboratory focuses on epithelial morphogenesis in Drosophila embryos, combining genetics, biophysics, and quantitative live imaging. Key research themes include: Mechanical regulation of tissue folding via apical constriction Actomyosin-dependent intracellular trafficking (e.g., Rab11 vesicle dynamics) Optogenetic control of contractility to probe force generation Roles of cell polarity determinants (e.g., Dlg1) in tissue-scale coordination Zygotic control of cortical myosin during cellularization His recent publications (2022) demonstrate a strong emphasis on real-time manipulation and measurement of biomechanical processes in developing epithelia, with recurring themes of actomyosin regulation, vesicle trafficking, and optogenetic perturbation. He leads the Bing He Lab at Dartmouth, utilizing advanced imaging and biophysical techniques to dissect how genetic programs interface with mechanical forces during morphogenesis.

Brittany Millerمشاهده پروفایل

استادیار

• Cell Biology
• Molecular Biology
• Microbiology
• +۳ مورد دیگر

Brittany Miller is an Assistant Professor of Biology with expertise in cell biology, molecular biology, and microbiology. Her research focuses on understanding cellular asymmetry and polarity through the study of the exocyst complex in budding yeast. She teaches courses in cell biology, genomics, and bioinformatics at the undergraduate and graduate levels. Education: PhD in Biology from University of North Carolina at Chapel Hill BA in Biology from St. Mary's College of Maryland Research Interests: Dr. Miller's lab investigates how cells maintain specialized shapes and functions through polarized exocytosis. Using genetic, cell biological, and biochemical tools in Saccharomyces cerevisiae, her work explores the molecular mechanisms of exocyst regulation and its role in disease pathways. Key areas include: Mechanisms of vesicle targeting and membrane trafficking Consequences of trafficking errors in tumorigenesis and disease Conserved pathways across eukaryotic organisms Advising & Labs: She mentors undergraduate researchers through independent study and honors thesis programs. Her lab utilizes yeast as a model system to study fundamental cellular processes with implications for human health.

Fen-Biao Gaoمشاهده پروفایل

استاد

• Neurodegenerative diseases
• Frontotemporal Dementia (FTD)
• Amyotrophic Lateral Sclerosis (ALS)
• +۵ مورد دیگر

Fen-Biao Gao is a Professor of RNA Therapeutics and Neurology at the University of Massachusetts Chan Medical School, holding the Paul Cellucci Chair in Neuroscience Research since 2017. He directs the Frontotemporal Dementia Research Center and is affiliated with the RNA Therapeutics Institute. Previously, he held roles at UCSF’s Gladstone Institute of Neurological Disease from 2000–2010. Education: PhD in RNA Biology from Duke University (1995), postdoctoral training at University College London (1995–1997) and UCSF (1997–2000). Research Focus: Investigates molecular mechanisms underlying FTD and ALS using Drosophila, mouse models, and patient-derived iPSCs. Key areas include RNA metabolism, polydipeptide repeat toxicity, and therapeutic interventions targeting C9ORF72 and TDP-43 pathways. His lab employs multidisciplinary approaches (molecular/cellular biology, genetics, and neurobiology). Recent Trends in Publications: Focuses on translational research linking basic molecular mechanisms (e.g., RNA repeats, autophagy defects) to neurodegenerative phenotypes. Highlights include CRISPR-based therapies, biomarker discovery, and drug targets like PIKFYVE inhibitors. Studies emphasize cross-talk between RNA dysfunction and cellular pathways (e.g., mitochondrial function, stress granules). Awards: NIH Javits Award (2018), McKnight Neuroscience Award (2002), and multiple fellowships. Active in professional service, including advisory roles for the Association for Frontotemporal Degeneration and Muscular Dystrophy Association. Lab & Collaborations: Current lab members include postdocs (e.g., Gopinath Krishnan, Soojin Lee) and graduate students. Collaborations span iPSC modeling, drug development, and genetic screening. Active in organizing conferences on RNA metabolism in neurodegenerative diseases.

Robert Robersonمشاهده پروفایل

دانشیار

• Cell Biology
• Mycology
• Fungal Morphogenesis
• +۳ مورد دیگر

Robert Roberson is an Associate Professor in the School of Life Sciences at Arizona State University (ASU), specializing in the Cellular and Molecular Biosciences department. He holds a Ph.D. in Plant Biology from the University of Georgia (1989) and an M.Sc. from Stephen F. Austin State University. His research focuses on cytoplasmic order and dynamics in fungal hyphal cells, utilizing advanced bioimaging techniques such as cryo-electron microscopy and confocal laser scanning microscopy. Key research organisms include Neurospora crassa, Allomyces macrogynus, and members of the Zygomycetes. Education: Ph.D., University of Georgia (1989); M.Sc., Stephen F. Austin State University. Research Interests: Fungal cell growth mechanisms, Spitzenkörper dynamics, microtubule and actin cytoskeleton organization, and the application of microscopy to study fungal ultrastructure. His work bridges molecular biology, cell biology, and evolutionary mycology to understand how cellular structures drive fungal morphogenesis. Grants and Collaborations: Principal investigator on NSF-funded projects including the ZyGoLife initiative and studies on cyanobacterial bioenergy. Collaborates with researchers in plant biology, microscopy, and synthetic biology. Teaching: Courses include BIO 495 Undergraduate Research , BIO 504 Bioimaging , and MCB 555 Advanced Molecular & Cellular Science . Service: Serves on editorial boards (e.g., Mycologia ), chairs microscopy-related committees, and advises on federal grant panels (NSF).