معرفی
Bing He is an Associate Professor in the Department of Biological Sciences at Dartmouth College, with joint affiliations in the Molecular and Cellular Biology Graduate Program and the Cancer Biology and Developmental Therapeutics Research Program at the Norris Cotton Cancer Center. His research employs interdisciplinary approaches to investigate mechanical aspects of tissue morphogenesis during embryonic development.
He holds a B.S. from Peking University and a Ph.D. from the University of Pennsylvania, specializing in mechanisms of cellular organization and developmental dynamics.
His laboratory focuses on epithelial morphogenesis in Drosophila embryos, combining genetics, biophysics, and quantitative live imaging. Key research themes include:
- Mechanical regulation of tissue folding via apical constriction
- Actomyosin-dependent intracellular trafficking (e.g., Rab11 vesicle dynamics)
- Optogenetic control of contractility to probe force generation
- Roles of cell polarity determinants (e.g., Dlg1) in tissue-scale coordination
- Zygotic control of cortical myosin during cellularization
His recent publications (2022) demonstrate a strong emphasis on real-time manipulation and measurement of biomechanical processes in developing epithelia, with recurring themes of actomyosin regulation, vesicle trafficking, and optogenetic perturbation.
He leads the Bing He Lab at Dartmouth, utilizing advanced imaging and biophysical techniques to dissect how genetic programs interface with mechanical forces during morphogenesis.
