جست‌وجوی استاد و پژوهشگر

Frank Oechslinمشاهده پروفایل

استادیار

• Bacteriophage
• Endolysins
• Phage Therapy
• +۴ مورد دیگر

Dr. Frank Oechslin is an Assistant Professor at the Department of Biochemistry, Microbiology and Immunology within the Faculty of Medicine at the University of Ottawa. He leads a research group focused on bacteriophages (phages) and their lytic enzymes (endolysins), investigating their potential to combat antibiotic-resistant bacteria. His lab is located in Roger Guindon Hall, Ottawa, Canada. PhD in Bacteriology, University of Lausanne, Switzerland Postdoctoral training at Université Laval, Québec (2018), supported by Swiss National Science Foundation Research interests span phage therapy, antimicrobial resistance, synthetic biology, and experimental evolution. His work employs CRISPR-Cas genome editing and advanced synthetic biology to explore phage-endolysin interactions, bacterial cell wall dynamics, and evolutionary adaptation mechanisms. Publications highlight thermostable endolysins, host specificity, and phage-antibiotic synergy. Scientific awards include a Swiss National Science Foundation Fellowship. His lab collaborates with Prof. Sylvain Moineau's team and focuses on engineering phages for clinical applications, particularly in treating infections caused by multi-drug-resistant pathogens like Pseudomonas aeruginosa and Streptococcus agalactiae .

Martin Loessnerمشاهده پروفایل

استاد

• Food Microbiology
• Bacteriophage Research
• Molecular Biology
• +۳ مورد دیگر

Prof. Martin Loessner is a Full Professor at the Department of Health Sciences and Technology, ETH Zurich, Switzerland. He leads the Institute of Food, Nutrition and Health, focusing on food microbiology and bacteriophage research. His work bridges fundamental molecular biology with practical applications in food safety and antimicrobial development. Education and Career: Martin Loessner earned a Biology degree from the Albert-Ludwigs-University of Freiburg, followed by an MSc from Wayne State University and a PhD in 1991 from the Technical University of Munich. He held postdoctoral and Research Assistant Professor roles at TU Munich, with visiting research stints at the University of Nottingham and Ben-Gurion University. After Habilitation, he became a Privatdozent (Assistant Professor with tenure) at TU Munich. Following a sabbatical as a Visiting Research Professor at UC Berkeley, he joined ETH Zurich as a Full Professor in 2003. Research Interests and Contributions: Loessner’s research centers on foodborne pathogens such as Listeria monocytogenes and Staphylococcus aureus, leveraging bacteriophages for detection and control. His group develops recombinant proteins for bacterial labeling, genetic engineering for safer food products, and CRISPR-based phage engineering. Key applications include antimicrobial enzybiotics, phage-based diagnostics, and treatments for biofilms and infections. Collaborations with industry and academia have led to several awards recognizing his contributions to food safety and microbiology. Research Trends in Recent Publications: Recent work emphasizes engineered bacteriophages for pathogen detection (e.g., reporter phages for urinary pathogens) and therapeutic applications (e.g., CRISPR-edited phages, bone-targeting enzymes). Innovations include nanoparticle-enhanced endolysins for biofilm eradication and strategies against phage-resistant L-form bacteria. These studies highlight advancements in synthetic biology, antimicrobial development, and diagnostic tools. Awards and Collaborations: His research has garnered multiple awards, though specific names are not detailed here. The group collaborates with academic institutions and industry partners in diagnostics and food safety. Teaching and Academic Contributions: Prof. Loessner teaches courses including “World Food System” and “Food Microbiology I,” reflecting his commitment to educating future scientists. His group’s work integrates research with practical solutions, addressing global challenges in food safety and infectious diseases. Labs and Teams: His research group at ETH Zurich’s Institute of Food, Nutrition and Health drives interdisciplinary projects, combining microbiology, synthetic biology, and engineering to combat pathogens and improve food safety standards.

Anne Seidlitzمشاهده پروفایل

استاد

• Pharmaceutical Technology
• Biopharmaceutics
• 3D Printing in Drug Delivery
• +۳ مورد دیگر

Anne Seidlitz is a Professor of Pharmaceutical Technology at the Free University of Berlin since October 2024, previously holding the same position at Heinrich Heine University Düsseldorf (2021-2024). Affiliated with the Institute of Pharmacy , she leads the Seidlitz Pharmaceutical Technology Group , focusing on solid dosage forms and biorelevant drug release studies using 3D printing and hydrogel compartments . Doctorate in Pharmaceutical Technology (Greifswald, 2009) Habilitation in Natural Sciences (Greifswald, 2015) Qualified Person under German Medicines Act (AMG) Visiting Professorships: Hamburg, Jena Research Interests: Formulation development for implants , intravitreal injections , and subcutaneous delivery systems , with emphasis on biorelevant dissolution testing under physiological flow/movement conditions. Her group pioneers 3D-printed drug delivery devices and custom hydrogel models for vitreal , ear canal , and vascular implants . Publication Trends: Recent articles focus on thermal stability of steroids during extrusion, individualized implant design , and hydrogel compartments for non-oral dissolution testing . Key collaborations include EUFEPS Network and APV (Association for Pharmaceutical Process Engineering). Scientific Involvement: Member of EUFEPS Network on Bioavailability Scientific Council, German Federal Chamber of Pharmacists Active in APV (Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik) Student Supervision: Mentored 24+ theses including 3D-printed tablets , implant coatings , and vitreal drug distribution . Collaborates with institutions in Düsseldorf , Jena , and Hamburg .

• Bacteriology
• Applied Microbiology
• Environmental Biotechnology
• +۴ مورد دیگر

Satoshi Tsuneda is a Professor at Waseda University’s School of Advanced Science and Engineering, attached to the Department of Life and Medical Sciences and jointly stationed at the Center for Advanced Biomedical Sciences (TWIns). Since earning his Ph.D. in Engineering from the University of Tokyo (1994) he has built a highly cited research program (> 15 800 citations, h-index 70) spanning environmental biotechnology and medical microbiology. Education: Doctor of Engineering, The University of Tokyo, 1994 Master of Engineering, The University of Tokyo, 1991 Bachelor of Engineering, The University of Tokyo, 1989 Research Interests: Tsuneda’s group integrates molecular microbiology with engineering to address global health and environmental challenges. They elucidate nitrification and anammox processes, design phage-based antimicrobials, decode bacterial persistence mechanisms, and develop microfluidic cultivation platforms. Their work links fundamental insights in bacteriophage biology, toxin-antitoxin systems, and nitrifying bacteria to practical applications in wastewater treatment, aquaculture, and alternative antimicrobials. Publication Trends: Recent articles (2022-2025) reveal two dominant directions: (i) phage engineering and phage cocktail design to combat multidrug-resistant E. coli and other pathogens, and (ii) ecophysiology of nitrifying bacteria (Nitrosomonas, Nitrotoga, anammox) aimed at optimizing nitrogen removal in engineered and natural systems. Additional themes include bacterial persistence, RNA toxin specificity, and micro-droplet technologies for high-throughput microbe isolation. Scientific Awards: Ministry of the Environment Director-General's Award for Environmental Regeneration and Resource Recycling (2022) Japan Society on Water Environment Distinguished Service Award (2022) Society for Biotechnology, Japan, Paper Award (2018) Nagase Science and Technology Foundation Research Promotion Award (2017) Multiple best-paper awards from JSWE, SCEJ, and SBTJ (2001-2014) Advising & Grants: Tsuneda currently advises a large cohort of graduate researchers; names of individual students are not listed in the supplied text. His laboratory has been continuously funded for interdisciplinary projects coupling microbiology with environmental engineering, although explicit grant numbers or titles are not provided. Laboratory & Teams: The Tsuneda Laboratory (est. 1996) operates within Waseda University and the TWIns joint research center, maintaining collaborations with Tokyo Women’s Medical University, Juntendo University, and AIST. The team specializes in molecular microbial ecology, phage isolation/engineering, and advanced bioreactor technologies.

Behrouz Zandieh Doulabiمشاهده پروفایل

پژوهشگر

• Tissue Engineering
• Biomaterials
• Nanomedicine
• +۴ مورد دیگر

Behrouz Zandieh Doulabi is a Researcher at the Academic Centre for Dentistry Amsterdam (ACTA) and a Visiting Professor at the University of Tehran since 2013. He is affiliated with the Department of Oral Cell Biology, focusing on interdisciplinary research at the intersection of cell biology, biomaterials, and tissue engineering. His primary research interests include osteosarcoma, stem cell applications, and nanomedicine, with a strong emphasis on bone biology and cell differentiation mechanisms. Dr. Doulabi has been actively involved in collaborative research projects, including studies on bone growth under microgravity conditions and the effects of biomaterials on osteoblast/osteoclast behavior. He holds ancillary academic roles at the University of Tehran, where he contributes to the Research Center for New Technologies in Life Sciences Engineering as a member since 2013. His recent work explores the impact of fluid shear stress on bone cell signaling and the role of paracrine factors in osteoclastogenesis. He has supervised five PhD theses and maintains an active publication record in high-impact journals such as npj Microgravity and Current Issues in Molecular Biology . Contact: bzandiehdoulabi@acta.nl | ORCID

Sierra Williamsمشاهده پروفایل

استادیار

• Protein Therapeutics
• Chemical Synthesis
• Protein Engineering
• +۳ مورد دیگر

Sierra Williams is faculty in the Chemistry department at the Keck Science Department of Claremont Colleges. She leads research focused on protein therapeutics and chemical synthesis to combat harmful pathogens. Her research interests include protein engineering, drug development, and improving endolysin activity for antimicrobial applications. Her lab employs chemical synthesis techniques to develop potential therapeutic agents. Her recent work trends show a strong focus on protein-based therapeutics, with particular attention to engineering approaches that enhance antimicrobial activity. The research spans biochemistry, chemical biology, and pharmaceutical development. Dr. Williams has successfully mentored numerous undergraduate researchers, many of whom have received competitive awards and secured positions in prestigious medical and graduate programs. Her lab was recently awarded a $457,000 NIH R15 grant to develop tools for improving endolysin activity, demonstrating significant research impact and funding success.

• Precision Fermentation
• Molecular Biotechnology
• Microbial Metabolic Engineering
• +۵ مورد دیگر

Lucília Domingues is an Associate Professor with Habilitation at the Biological Engineering Department of University of Minho's School of Engineering. She serves as Director of the Master Course on Biotechnology and Deputy Director of the Centre of Biological Engineering (CEB) research unit. With over two decades of academic experience, she leads the Molecular Biotechnology and Precision Fermentation research group and maintains active collaborations with international institutions including a 2024 Visiting Professorship at the Biological Engineering Center at the University of Kobe. Her educational background includes a Chemical Engineering degree from University of Porto (1994) with an ERASMUS stay at Universitat Politècnica de Catalunya, a Master in Biotechnology - Bioprocess Engineering (1997), a PhD in Chemical and Biological Engineering (2001) in collaboration with VTT Technical Research Center of Finland, and Habilitation in Chemical and Biological Engineering (2018), all from University of Minho. Professor Domingues' research focuses on Molecular and Industrial Biotechnology, particularly developing microbial cell factories using molecular biotechnology tools for eco-sustainable production of biofuels and bio-based chemicals. Her work emphasizes renewable substrates and applications across food, energy, chemical and biomedical industries. She has pioneered approaches in precision fermentation, microbial metabolic engineering, and biorefinery development for lignocellulosic biomass valorization. Her publication record demonstrates consistent high-impact research across biotechnology domains, with particular emphasis on yeast engineering, waste valorization, and sustainable production systems. The research shows strong integration of molecular biology techniques with industrial applications, especially in developing microbial systems for bio-based chemical production from renewable resources. World's Top 2% Scientists (2021, 2022, 2023) Research Merit Prize (2021, 2022, 2023) Scientific Merit Award 2022 from School of Engineering Professor Domingues has extensive experience supervising graduate researchers with 51 Master's and 23 PhD students completed. She has coordinated numerous national and European funded projects including New protein-based technology platform for mycotoxin purification, EssenTial, Biostarv, and YEaSt innovation. Her research group actively collaborates with industrial partners on molecular biotechnology and biorefineries development. She serves as Associate Editor for Biotechnology for Biofuels and Bioproducts and editor for Bioengineered and Biomed Research International. Her laboratory, the Molecular Biotechnology Laboratory (LBM), focuses on developing advanced microbial systems for precision fermentation and sustainable bioproduction. The research team works at the intersection of molecular biology, metabolic engineering, and bioprocess development to create innovative solutions for industrial biotechnology challenges.

• Orthopedics
• Bone Research
• Translational Medicine
• +۳ مورد دیگر

Prof. Petrus Nolte is an Endowed Professor in Oral Cell Biology at the Academic Centre for Dentistry Amsterdam (ACTA). He concurrently serves as a surgeon at Spaarne Gasthuis Hospital in Hoofddorp, holding an ancillary role since 2003. His primary affiliation is with ACTA, where he focuses on translational dental and bone research, particularly in orthopedics. Nolte’s research emphasizes prosthetic joint infections, bone regeneration, and implant biocompatibility, bridging clinical and experimental studies. His work integrates cell biology, biomaterials, and clinical outcomes in orthopedic applications. Research Interests: His specialties include Total Knee Arthroplasty, osteoclast biology, biofilm treatment, and prosthetic infection management. He explores endolysin-based therapies for MRSA biofilms and investigates implant surface effects on bone cell behavior. Recent studies focus on antibiotic combination therapies for prosthetic joint infections and long-term outcomes of knee implant systems. Education: PhD research on unhealed bone at ACTA, foundational to his translational bone research. Awards: None explicitly mentioned in the text. Grants/Supervised Work: Supervised 2 PhD theses. Collaborates on clinical trials like the RiCOTTA-trial for prosthetic infection protocols. Labs/Teams: Engaged with multidisciplinary teams at ACTA and Spaarne Gasthuis, focusing on translational orthopedic and dental research. Leads studies on implant materials and biofilm therapies, with datasets available on platforms like Figshare.

• Bacteriophage Therapy
• Antimicrobial Resistance
• Protein Engineering
• +۳ مورد دیگر

Niels Vander Elst is a Postdoctoral Researcher at the Department of Neuroscience, Karolinska Institutet, affiliated with the Neuro-infections & Neuroinflammation research group led by Federico Iovino. He specializes in bacteriophage-derived endolysins as innovative antimicrobials to combat antibiotic-resistant infections, particularly in Gram-positive pathogens such as Streptococcus and Staphylococcus . Dr. Vander Elst holds a dual PhD in Biotechnology and Veterinary Medicine from KU Leuven and Ghent University, funded by the Research Foundation Flanders (FWO), and conducted research at the University of Maryland under a fellowship from the Belgian American Educational Foundation (BAEF). His research focuses on: Bacteriophage therapy and endolysin engineering Antibiotic resistance reversal mechanisms Neuro-infections and blood-brain barrier penetration Veterinary applications of antimicrobials Protein engineering and synthetic biology approaches His publications demonstrate a progression from veterinary applications toward human medical innovations, with recent work focusing on restoring antibiotic susceptibility in resistant pathogens and treating central nervous system infections. Earlier research established foundational work on bovine mastitis therapeutics. Honors include: Finalist for University of Maryland's 'Invention of the Year' (2020) Award recipient at the Encephalitis Meeting in London (2024) Significant grants supporting his work: Kronprinsessan Lovisas Förening (2023, 2025): Endolysins for pneumococcal meningitis treatment Fonds Wetenschappelijk Onderzoek (2020-2023): Engineering endolysins for bovine mastitis Belgian American Educational Foundation (2019): Bacteriophage-endolysin therapy development Beyond research, Dr. Vander Elst teaches neurohistology in KI's medical curriculum, serves in the Junior Faculty Leadership, and promotes open science initiatives. He actively communicates scientific advancements through public outreach articles on phage-based antimicrobials.

Christian Dzuvorمشاهده پروفایل

پژوهشگر ارشد

• Vaccinology
• Emerging Infectious Diseases
• Antibody Therapeutics
• +۶ مورد دیگر

Christian Dzuvor is a Post-Doctoral Research Fellow at Harvard University's T.H. Chan School of Public Health and Department of Immunology and Infectious Diseases. Previously, he completed his PhD in Chemical and Biological Engineering at Monash University (2019–2022) and holds a BSc (Hons) in Chemical Engineering from Kwame Nkrumah University of Science and Technology (KNUST), Ghana (2017). His research focuses on integrating protein engineering, nanotechnology, and immunology to develop novel vaccines, antibody therapeutics, and antimicrobial agents against emerging pathogens like coronaviruses and drug-resistant bacteria. Education: PhD in Chemical and Biological Engineering, Monash University (2019–2022) BSc (Hons) in Chemical Engineering, KNUST (2013–2017) Research Interests: Viral immunology, universal vaccine design, protein nanotechnology, antimicrobial peptides, and interdisciplinary approaches to pandemic preparedness. He is particularly inspired by his mentor Prof. Kizzmekia S. Corbett (designer of the Moderna SARS-CoV-2 vaccine) to engineer safe and effective vaccines and antibodies for future pandemics. Awards & Honors: Distinguished Global Talent Awardee (Australian Government, 2020) Monash Graduate Research Scholarship (2019–present) International Postgraduate Research Scholarship (2019–present) Grants & Collaborations: His PhD research was supported by an ARC grant (DP210103595) focusing on peptide-based nanoparticles against superbugs. Current work at Harvard emphasizes viral immunology and universal vaccine development. Labs & Teams: Works in Prof. Kizzmekia S. Corbett's lab at Harvard, focusing on immunological approaches to combat emerging viral threats. Active in networks like VIIN (Victorian Infection and Immunity Network) and Ausbiotech.

Pål Stenmarkمشاهده پروفایل

استاد

• Botulinum neurotoxins
• Enzyme catalysis
• Neurotoxicity
• +۳ مورد دیگر

Pål Stenmark is a Professor of Biochemistry at the Department of Biochemistry and Biophysics , Stockholm University. His research focuses on botulinum neurotoxins and structure-based drug design , particularly targeting enzymes in nucleotide metabolism for cancer therapy. Research Interests Elucidating the molecular mechanisms of botulinum neurotoxins using X-ray crystallography and cryo-EM . Developing novel cancer drugs through structural insights into proteins like MTH1 and OGG1 , which are critical for managing oxidative DNA damage. Applying interdisciplinary collaborations to refine inhibitors for therapeutic applications. Scientific Awards Awarded a grant from the Swedish Brain Foundation (Hjärnfonden) in 2023 for research on ALS, Epilepsy, and Alzheimer's. Students and Collaborators Supervises a team including PhD students and postdocs such as Chloe Leveque , Maria Nowakowska , and Ellen Walse . Laboratory members engage in projects spanning protein structure , neurotoxin interactions , and nanobody tools for synaptic imaging. Publications His recent work explores trends in botulinum toxin engineering , OGG1 activation , and endolysin structures for food safety applications.

• Recombinant Protein Engineering
• Bacterial Inclusion Bodies
• Antimicrobial Peptides
• +۵ مورد دیگر

Elena Garcia Fruitós is a Researcher at the Department of Genetics and Microbiology, Universidad Autónoma de Barcelona, and a CIBER Research staff member at the Institute of Biotechnology and Biomedicine "Vicent Villar Palasi" (IBB). With an h-index of 33 and over 3046 citations, she has established herself as a leading expert in recombinant protein engineering and bacterial expression systems. Her research focuses on bacterial inclusion bodies, recombinant protein production in Escherichia coli, and the development of antimicrobial peptides. Dr. Garcia Fruitós has pioneered approaches that transform inclusion bodies from production artifacts into functional protein nanoparticles with applications in drug delivery and nanomedicine. Her work bridges fundamental molecular biology with practical pharmaceutical applications, particularly in developing novel antimicrobial strategies against resistant pathogens. Analysis of her 103 research outputs reveals a consistent trajectory toward increasingly sophisticated protein engineering techniques, with recent work focusing on tailored antimicrobial drugs based on recombinant multidomain proteins and advanced heterologous expression systems. Her publications demonstrate strong interdisciplinary connections between microbiology, molecular biology, and pharmaceutical sciences. Dr. Garcia Fruitós has secured significant research funding through multiple competitive grants, including the long-term CIBER BBN research group on Applied Microbiology at IBB-UAB (2009-2030), personalized nanomedicine for triple negative breast cancer stem cells (2014-2017), and strategies for high-quality microbial production of therapeutic enzymes (2009-2012). She has supervised six research projects and collaborates extensively with researchers across Spain and internationally.

• Pharmaceutical Science
• Drug Delivery Systems
• Inhalation Therapy
• +۳ مورد دیگر

Dr Waiting Tai is a Researcher at the Sydney Pharmacy School, part of the Faculty of Medicine and Health at the University of Sydney. His work focuses on advanced drug delivery systems, particularly inhalation therapies and pharmaceutical formulation innovations. Key areas include aerosol drug design, nanoparticle engineering for bioavailability improvement, and targeted therapies for neurological and infectious diseases. His research integrates analytical techniques like O-PTIR spectroscopy for particle characterization and explores novel approaches such as bacteriophage endolysin powders for pulmonary infections. Recent studies emphasize CBD delivery mechanisms, anti-biofilm agents in antibiotic formulations, and aerosolized treatments for conditions like tuberculosis and COVID-19. Dr Tai’s publications highlight interdisciplinary collaboration between pharmaceutical science and biomedical engineering, aiming to bridge gaps between formulation science and clinical application. His research interests span pharmaceutical aerosol technology, nanomedicine for CNS delivery, and the development of stable inhalable powders. Notable projects include high-loading CBD powders, spray-freeze-dried formulations with DPPC, and in vitro/in vivo correlations for aerosol performance. While no scientific awards are explicitly listed, his contributions reflect significant innovation in respiratory drug delivery systems.

Petr Leimanمشاهده پروفایل

دانشیار

• Structural Biology
• Bacteriophage Research
• Molecular Biophysics
• +۴ مورد دیگر

Petr Leiman is an Associate Professor in the Department of Biochemistry & Molecular Biology at the University of Texas Medical Branch (UTMB). His research focuses on structural biology and molecular mechanisms of bacteriophages and bacterial secretion systems. University: University of Texas Medical Branch Department: Biochemistry & Molecular Biology Academic Rank: Associate Professor Dr. Leiman’s work aims to elucidate the atomic-level structures and functional mechanisms of biological nanomachines, particularly the bacterial type VI secretion system (T6SS) and R-type pyocins. These systems are studied through techniques such as X-ray crystallography, cryo-electron microscopy, and biochemical analysis. His research explores the parallels between phage tail structures and bacterial pathogenicity determinants, with implications for antimicrobial development. Recent publications highlight structural insights into phage Milano’s disulfide bond network, T6SS toxin containers, and viral RNA polymerase promoter recognition. His grants include NIH R35 and R01 awards, as well as collaborations with Lawrence Berkeley National Laboratory for phage foundry platforms targeting drug-resistant pathogens.

• Biotechnology
• Protein Engineering
• Bacterial Inclusion Bodies
• +۴ مورد دیگر

Elena Garcia Fruitos is a senior researcher at the Institute of Agrifood Research of Catalonia (IRTA) , specializing in ruminant production biotechnology . Her work focuses on leveraging bacterial inclusion bodies for biomedical applications, protein nanomaterials, and sustainable agrifood technology. Key Projects: Antibiotic residue degradation in milk, protein-based antimicrobial surfaces, and dry-off period optimization in dairy cows Research Themes: Protein self-assembly, inclusion body engineering, food-grade microbial production systems Her 2025-2022 publications highlight innovations in antimicrobial peptides, thermoplastic surface activation, milk waste valorization, and advanced protein delivery systems. Scientific Collaborations include multidisciplinary teams in bioengineering, veterinary medicine, and nanotechnology.