Petr Leiman

Petr Leiman is an Associate Professor in the Department of Biochemistry & Molecular Biology at the University of Texas Medical Branch (UTMB). His research focuses on structural biology and molecular mechanisms of bacteriophages and bacterial secretion systems.

• University: University of Texas Medical Branch
• Department: Biochemistry & Molecular Biology
• Academic Rank: Associate Professor

Dr. Leiman’s work aims to elucidate the atomic-level structures and functional mechanisms of biological nanomachines, particularly the bacterial type VI secretion system (T6SS) and R-type pyocins. These systems are studied through techniques such as X-ray crystallography, cryo-electron microscopy, and biochemical analysis. His research explores the parallels between phage tail structures and bacterial pathogenicity determinants, with implications for antimicrobial development.

Recent publications highlight structural insights into phage Milano’s disulfide bond network, T6SS toxin containers, and viral RNA polymerase promoter recognition. His grants include NIH R35 and R01 awards, as well as collaborations with Lawrence Berkeley National Laboratory for phage foundry platforms targeting drug-resistant pathogens.