جستجوی استاد راهنمای دانشگاهی

Zelmina Lubovac is a Senior Lecturer in BioInformatics at the School of Bioscience, University of Skövde. She serves as both a Course Coordinator for multiple undergraduate and graduate courses in bioinformatics and a Programme Coordinator for Master's level programs. Her academic work focuses on the intersection of computational methods and biological applications, particularly in disease analysis and biomarker discovery. Dr. Lubovac's research spans several key areas in bioinformatics and systems biology: Disease module identification in complex biological networks Multi-omics integration (genomics, proteomics, metabolomics) for biomarker discovery Machine learning applications in RNA-seq and other high-throughput biological data Development of bioinformatics software tools for network analysis miRNA analysis in cancer and neurological disorders Her recent publications (2022-2024) demonstrate a strong focus on applying computational approaches to understand disease mechanisms, particularly in pancreatic cancer and multiple sclerosis. She has developed several widely-used bioinformatics tools including MODalyseR, MODifieR, and TFTenricher that facilitate disease module analysis and gene network interpretation. Her work often involves collaborative research with clinical teams to translate computational findings into potential diagnostic applications. Dr. Lubovac has been involved in significant research projects including: BIO-AID (Biomedical AI-driven data analytics): Oct 2020 - Sep 2024 Systems Biology DMDPipe: Mar 2018 - Feb 2021 She actively contributes to both undergraduate and graduate education at the University of Skövde, coordinating multiple courses and programs in bioinformatics and bioscience, with a clear emphasis on preparing students for careers at the intersection of biology and computational science.

• Bioinformatics
• Systems Biology
• Disease Module Identification
• +۶ مورد دیگر

Jonas Stålhand is a Professor at Linköping University, affiliated with the Department of Management and Engineering (IEI) and the Division of Solid Mechanics (SOLMEK). His research focuses on biomechanics, smart textiles, haptic technologies, and cardiovascular mechanics. He leads interdisciplinary projects such as a study on pain relief using smart textile garments, combining neuroscience, materials science, and biomechanics. His work spans arterial wall mechanics, wearable haptic systems, and biomaterial characterization. Recent projects include parameter identification in arteries and the development of electroactive yarn actuators for wearable applications. Collaborations involve multidisciplinary teams across engineering, medicine, and textile science. Research interests emphasize translating biomechanical insights into clinical and industrial applications. Notable contributions include studies on aortic stress analysis, acetabular cup stability, and electroactive polymer-based actuators. His publications address both fundamental and applied aspects of soft tissue mechanics and medical engineering. No scientific awards are explicitly listed, but his work has been highlighted in university news for its innovative potential in healthcare and technology.

• Biomechanics
• Medical Engineering
• Materials Science
• +۳ مورد دیگر

Niklas Björkström is a Professor/Specialist Physician at Karolinska Institutet (KI) in Sweden, affiliated with the Department of Medicine, Huddinge. He leads the Human tissue-resident NK cells research group and is based at the Center for Infectious Medicine (CIM). His dual role combines academic leadership with clinical work at Karolinska University Hospital's Clinical Microbiology department. Education: Björkström earned his MD (2010) and PhD (2011) in Immunology from KI. He completed postdoctoral training at the National Institutes of Health (NIH), USA, before returning to KI as a Principal Investigator in 2014 and becoming a Professor in 2023. He holds an Associate Professor title (2016). Research Interests: His laboratory focuses on understanding human tissue-resident lymphocytes, particularly natural killer (NK) cells, in the liver, uterus, and other organs. Key areas include NK cell biology in liver diseases (e.g., PSC, NASH, hepatitis viruses) and pregnancy immunology. Techniques used include high-dimensional flow cytometry, CyTOF, microscopy, and computational tools (e.g., SPADE, SNE). The group collaborates with Hannover Medical School and the International PSC Study Group. Awards: Björkström has received prestigious honors such as the ERC Starting Grant (2020), Anders Jahre Award (2020), and NovoNordisk Foundation Emerging Investigator (2021). He is also a Wallenberg Academy Fellow (2017–2021). Grants & Advising: He oversees grants like the Swedish Cancer Foundation (2021–2023) and Karolinska Institutet's KID and Assistant Professor Tenure Track grants. Advised students include Christine Zimmer (PhD), Lena Berglin, and others now in postdoc roles or industry positions. Labs & Teams: The Björkström group is part of KI's Department of Medicine, Huddinge, and maintains close ties with clinical units at Karolinska University Hospital. They have open postdoctoral positions and collaborate internationally on liver and pregnancy immunology projects.

• Immunology
• Infectious Medicine
• Cancer Immunology
• +۴ مورد دیگر

Lou Brundin is a Professor/Senior Physician at Karolinska Institutet , leading the Stemcells and inflammation research group within the Department of Clinical Neuroscience. He holds academic appointments including Head of the Neurology Section since 2011 and has been a Professor since 2008. Education: MD (Karolinska Institutet, 1987), PhD in Sensory Physiology (1991), and postdoctoral training at the University of Sussex (1991–1992). His career includes roles as Vice President of R&D at Karolinska Hospital (2001–2003) and Director of Studies in Neurology since 2004. Research Focus: Neural stem cell biology, neuroinflammation, and multiple sclerosis (MS). His group investigates mechanisms of neural repair through stem cells and inflammatory pathways, aiming to enhance CNS regeneration. Key areas include oligodendrocyte remyelination, nitric oxide effects on neurogenesis, and mesenchymal stem cell therapies. Publications: Over 50 peer-reviewed articles, with recent work on T cell autoantigens in MS, mesenchymal stem cell trials, and neuroinflammatory mechanisms. His research bridges clinical neurology and experimental neuroscience. Awards: 2009 Swedish Society of Neurology's Golden Hammer Teaching Prize for educational excellence. Advising & Leadership: Supervised 5 PhD students and co-supervised 3. Currently mentors 2 PhD students and 3 postdocs. Active in academic governance, including national neurology curriculum boards. Labs/Teams: Leads a 10-member interdisciplinary team combining neurology, neurosurgery, and neurobiology. Collaborates on translational projects like the MESEMS clinical trial for MS therapies.

• Neuroimmunology
• Stem Cell Biology
• Multiple Sclerosis
• +۳ مورد دیگر

Mikael Hedeland is a full Professor at the Department of Medicinal Chemistry (Analytical Pharmaceutical Chemistry), Uppsala University , where he has worked since 1999. He holds a PharmD and was appointed Docent (associate professor) in 2007. Visiting Professor (2013) Adjunct Professor (2015) Full Professor (2018) His research focuses on bioanalysis of drugs and metabolites using chromatography-mass spectrometry , with applications in doping control , pharmacokinetics , and mass spectrometry methods for botulinum neurotoxin detection . He leads multidisciplinary collaborations with experts in biopharmaceutics , veterinary medicine , and environmental toxicology . Recent publications emphasize LC-MS/MS method development for PROTACs , lipidomics in cancer therapy , and metabolomics of arginine derivatives in pregnancy complications . His work includes environmental biodegradation studies using Trametes versicolor and chiral separations via supercritical fluid chromatography .

• Mass Spectrometry
• Chromatography
• Bioanalysis
• +۵ مورد دیگر

Zelmina Lubovac-Pilav is a Senior Lecturer in Bioinformatics at the School of Bioscience, University of Skövde. She coordinates advanced and foundational courses in bioscience and serves as Programme Coordinator for Master's-level programs. Her research focuses on bioinformatics , systems biology , and disease module analysis , particularly in pancreatic cancer , multiple sclerosis , and breast cancer . Her work involves multi-omics data integration (genomics, proteomics, transcriptomics) and biomarker discovery , supported by projects like BIO-AID (AI-driven biomedical analytics) and DMDPipe (disease-causing protein modules in asthma). She develops computational tools such as MODalyseR and TFTenricher for disease module inference and transcription factor analysis. The 15 most recent articles highlight trends in latent space modeling , network biology , and clinical data analysis , with applications in pancreatic cancer early detection , multiple sclerosis biomarkers , and miRNA functional analysis . These studies emphasize algorithm development , data normalization , and community-driven network predictions . Contact: zelmina.lubovac@his.se

• Bioinformatics
• Systems Biology
• Computational Biology
• +۷ مورد دیگر

Erik Johansson is a Professor and Head of the Department of Medical Biochemistry and Biophysics at Umeå University. His research focuses on understanding the molecular mechanisms of DNA replication, particularly the role of DNA polymerase epsilon (Pol ε) in leading-strand synthesis, genome stability, and cancer-associated mutations. His work combines structural biology, enzymology, and genetic approaches to elucidate how Pol ε ensures high-fidelity DNA replication and prevents genomic instability. Research Interests: - DNA replication fidelity and error correction - Structural and functional analysis of DNA polymerases - Cancer-associated mutations in replication machinery - Mitochondrial DNA instability - Regulation of histone segregation during replication Key Findings: - Pol ε's proofreading domain mutations drive cancer through replication errors. - Fe-S clusters in Pol ε modulate enzymatic activity and redox signaling. - Nicks in DNA can trigger localized re-replication, promoting genomic instability. Selected Awards: None explicitly stated in the text. Lab & Collaborations: The Erik Johansson Lab at Umeå University investigates how eukaryotic cells replicate DNA with high accuracy. Current projects include studying Pol ε's role in leading-strand synthesis, structural consequences of cancer mutations, and mechanisms preventing genome re-replication from DNA nicks.

• DNA Replication
• Cancer Genetics
• Genome Stability
• +۳ مورد دیگر

Klara Asplund Högelin is a researcher at the Department of Laboratory Medicine , Karolinska Institutet, specializing in neuroimmunology with a focus on multiple sclerosis (MS) and viral interactions. Her work explores T cell autoreactivity, B cell dynamics under immunosuppressive therapies, and neuroinflammatory biomarkers. Key studies include: Identification of novel MS autoantigens (FABP7, PROK2, RTN3, SNAP91) Analysis of SARS-CoV-2 immune memory in B cell-depleted MS patients Investigation of intrathecal virus-specific immune responses in MS HLA associations with autoreactive T cell profiles Her research integrates clinical immunology with neuroinflammatory mechanisms, utilizing advanced techniques like FluoroSpot assays and suspension bead arrays. Publications span journals such as Science Advances , Allergy , and Mult Scler J . Collaborations include the Peter Bergman Research Group and international MS consortia. Current work aims to translate autoantigen discoveries into diagnostic tools and immunomodulatory therapies.

• Neuroimmunology
• Autoimmune Diseases
• Neuroinflammation
• +۴ مورد دیگر

Ulf Bondesson is a Visiting Professor in the Department of Medicinal Chemistry, Analytical Pharmaceutical Chemistry at Uppsala University. His work focuses on pharmacology, veterinary medicine, drug metabolism, and doping control, employing advanced analytical techniques like mass spectrometry and liquid chromatography. Key collaborations: Mikael Hedeland, Curt Pettersson, Heather K. Knych Research areas: Equine drug metabolism, SARM detection, arginine pathway in cardiovascular disease His recent publications analyze metabolite profiling of selective androgen receptor modulators (SARMs) in horses, pharmacokinetics of antibiotics in swine, and arginine-related biomarkers in preeclampsia. Studies often integrate high-resolution mass spectrometry , multivariate data analysis , and comparative in vitro/in vivo models . Notable trends include: improved doping control protocols , cross-species metabolite prediction , and pharmacokinetic modeling in veterinary contexts . Techniques like Cunninghamella elegans biotransformation and TEMPO derivatization are recurrent themes.

• Pharmacology
• Analytical Chemistry
• Veterinary Medicine
• +۴ مورد دیگر

Dr. Andreas Kohler is an Assistant Professor at the Department of Medical Biochemistry and Biophysics at Umeå University, Sweden. He leads the Andreas Kohler Lab , focusing on mitochondrial protein quality control (PQC) mechanisms and their roles in health, ageing, and disease. His research uses yeast ( Saccharomyces cerevisiae ) and human cell models to study mitochondrial PQC of proteins encoded by mitochondrial DNA, particularly how these processes change with age and contribute to neurodegenerative disorders like Parkinson's. Research interests include mitochondrial biology, protein folding, cellular stress response, and the interplay between mitochondrial dysfunction and ageing. His work bridges fundamental biochemistry with translational applications, aiming to identify therapeutic targets for age-related diseases. Publications from 2020-2024 highlight contributions in mitochondrial supercomplexes, prion modulation of respiratory chain defects, and multi-omic data integration using machine learning. He collaborates widely, with recent studies published in Nature Communications , Molecular Cell , and EMBO Reports . He serves as Equal Opportunities Representative for his department and actively promotes diversity in academia. His lab website ( kohler-mitolab.com ) provides further research details and outreach activities.

• Medical Biochemistry
• Mitochondrial Biology
• Protein Quality Control
• +۵ مورد دیگر

Lindon Moodie is an Associate Professor at Uppsala University's Department of Medicinal Chemistry; Drug Design and Discovery, affiliated with the Uppsala Antibiotic Centre. His research integrates synthetic organic chemistry and chemical biology to explore antibiotic discovery, gut microbiome interactions, and small-molecule modulation of host physiology. He holds a PhD in Chemistry (2013) from the University of Otago, New Zealand, and previously worked at the University of Tromsø and Umeå University. Research Interests: Moodie's work focuses on: Developing novel antibiotics using medicinal chemistry approaches. Investigating the impact of small molecules on the human microbiome and bacterial physiology. Designing strategies to selectively target pathogenic bacteria while preserving commensal microbes. Applying marine-derived compounds for antifouling and antimicrobial applications. Publication Trends: His recent articles (2020–2025) emphasize: Antibiotic delivery systems (e.g., nanoparticle therapies). Marine natural products as antifoulants and antimicrobials. Analytical methods for dissolved organic matter characterization. Broad-spectrum antiviral agents and peptide engineering. Additional Affiliations: Moodie collaborates with the Uppsala Antibiotic Centre, focusing on interdisciplinary solutions for antibiotic resistance.

• antibiotic discovery
• organic chemistry
• gut microbiome
• +۳ مورد دیگر

Rebecca Wall is a Senior Lecturer at the School of Medical Sciences, Örebro University, where she has been employed since joining as a research associate in July 2014. She is affiliated with the Department of Medical Sciences and contributes significantly to both research and teaching within the Medical Programme. Dr. Wall's educational background includes: PhD in Microbiology from University College Cork, Ireland (2008) Master's Degree in Chemistry from the University of Kalmar, Sweden (2003) Her research primarily focuses on the intricate relationship between diet, gut microbiota, and host health. Dr. Wall specializes in studying how dietary fibers modulate the microbiota and influence host health and disease, with particular emphasis on butyrate - a microbial metabolite produced from bacterial fermentation of undigested dietary fibers in the large intestine. Her work explores butyrate's mode of action in the human colon and its importance for colonic health, particularly in relation to inflammatory bowel diseases such as IBD and IBS. Through her leadership of the Nutrition-Gut-Brain Interactions Research Centre (NGBI) and Responsive Nutrition Research Centre, she investigates the complex gut-brain axis and how microbial metabolites affect host physiology. Analysis of Dr. Wall's publication record reveals a consistent research trajectory centered on gut microbiome interactions, with increasing focus on the gut-brain axis in recent years. Her work spans from basic microbial ecology to clinical applications, with strong translational potential in treating metabolic and inflammatory disorders. The interdisciplinary nature of her research is evident in publications spanning microbiology, nutrition, gastroenterology, neuroscience, and systems biology. Dr. Wall serves as principal investigator for multiple successful research grants from prestigious funding bodies including The Swedish Research Council (Vetenskapsrådet and Formas) and The European Foundation for the Study of Diabetes. She has established extensive national and international collaborations, with strong partnerships bridging academia and industry to advance translational research in gut microbiome science. Within the educational framework, Dr. Wall is co-responsible for coordinating the "nutrition, metabolism and elimination" (NME) theme area during semesters 1, 2, 5 and 8 of the Medical Programme, and serves as course coordinator and examiner for the Independent Project (15 higher education credits) during semester 6. Her teaching integrates cutting-edge research findings with medical education to provide students with a comprehensive understanding of how gut microbiome research informs clinical practice. Dr. Wall leads several active research projects including "Effect of serotonergic stimulation on the gut-brain axis in irritable bowel syndrome patients," "Effects of dietary fiber supplementation on intestinal barrier function," and "Identification of dietary fibers that promote butyrate production." Her lab is part of the Nutrition-Gut-Brain Interactions Research Centre, Diabetes Endocrinology and Metabolism group, and The Ageing Gut (TAG) research team, creating a multidisciplinary environment for investigating the complex interactions between diet, microbiota, and host physiology across the lifespan.

• Gut Microbiome
• Nutrition-Gut-Brain Axis
• Butyrate Research
• +۵ مورد دیگر

Tirthankar Mohanty is an Associate Researcher at Lund University's Biomedical Center (BMC), Department of Infection Medicine, specializing in translational sepsis research. His work intersects proteomics, infectious diseases, and inflammation dynamics. Key Research Areas: Proteomics, Sepsis, HIV-1 infection, Pulmonary fibrosis, Neutrophil extracellular traps (NETs) Notable Projects: Physiological methods to reduce sepsis in prostate biopsies, DNase treatment in COVID-19 recovery Methodologies: Mass spectrometry, Digital twin modeling, Pharmacoproteomics His publications focus on blood plasma proteome dynamics, inflammation regulation via serum amyloid A proteins, and OGG1 inhibition in lung fibrosis. Recent work includes creating a human proteome distribution atlas for tissue-specific analysis and developing a Streptococcus pyogenes vaccine using epitope-centric nanoparticles. Scientific Impact: Collaborations span multiple institutions, with 21 research outputs including 19 peer-reviewed articles, 1 doctoral thesis, and 1 preprint. His research contributes to UN Sustainable Development Goals in health and well-being.

• Proteomics
• Infectious Medicine
• Hematology
• +۶ مورد دیگر

Lasse Jensen is a Senior Associate Professor at Linköping University's Department of Health, Medicine and Caring Sciences (HMV), part of the Faculty of Medicine and Health Sciences (MEDFAK). His research focuses on functional precision medicine using zebrafish tumor xenograft models to individualize cancer treatment, vascular dysfunction in diseases like cancer and retinopathies, and sleep disruption in oncology patients. He holds a Master of Engineering (Biotechnology) from DTU (2005) and a PhD in Medical Sciences from Karolinska Institutet (2010). After postdoctoral roles at Karolinska and Linköping, he became a lecturer and later Senior Associate Professor (since 2018). His research spans three main areas: 1) Zebrafish PDX models for personalized cancer therapy, supported by grants like ALADDIN and EVEREST; 2) Vascular mechanisms in eye and brain diseases, including hypoxia-driven angiogenesis; and 3) Sleep disruption's impact on cancer treatment outcomes. He collaborates with institutions like Karolinska and Jönköping University on clinical studies. Key articles (2024–2025) highlight advancements in zebrafish models predicting treatment efficacy, anti-angiogenic strategies, and sleep assessment tools for cancer patients. He supervises PhD students and teaches courses like 'Cardiovascular Biology.' His work bridges basic science with clinical applications, emphasizing translational oncology and vascular biology.

• Cancer Research
• Vascular Biology
• Precision Medicine
• +۷ مورد دیگر

Alejandro Rodríguez González is a Full Tenured Professor at the Computer Languages and Systems and Software Engineering Department of Universidad Politécnica de Madrid , where he has held academic positions since 2015. He leads the Medical Data Analytics Laboratory (MEDAL) at the Centro de Tecnología Biomédica . His academic career includes previous roles at Universidad Internacional de La Rioja (2012-2015), Universidad de Oviedo (2015), and Universidad Carlos III de Madrid (2011-2012). His research focuses on Biomedical Informatics , Network Medicine , and Computational Drug Repurposing . Key areas include artificial intelligence applications in healthcare, clinical natural language processing , and health data ecosystem transparency . He has developed ontologies like EBOCA and contributed to platforms including DISNET for rare disease research and DRIVE for disease visualization. Recent publications demonstrate expertise in protein folding prediction analysis , scRNA-seq integration , and graph neural network applications in drug repurposing. His work emphasizes biological pathway analysis , gender perspectives in pharmacology , and AI-driven disease network modeling . He has secured funding from H2020 , EIT Health , and Ministerio de Ciencia e Innovación . Scientific Awards : Best Research Trajectory Award (UPM, 2017) II Premio al espíritu innovador (Treelogic, 2008) Mejor Idea EUITIO (CEEI Asturias, 2008) He contributes to ERC grant proposal writing , serves on editorial boards for journals like International Journal On Advances in Intelligent Systems , and participates in conferences such as IEEE CBMS and Health Informatics Conference . His technical projects involve Semantic Web Services , Heterogeneous Data Integration , and IoT security frameworks .

• Biomedical Informatics
• Artificial Intelligence in Healthcare
• Network Medicine
• +۵ مورد دیگر