جست‌وجوی استاد و پژوهشگر

Roger Barkerمشاهده پروفایل

استاد

• Neurodegenerative Disorders
• Parkinson's Disease
• Huntington's Disease
• +۴ مورد دیگر

Roger Barker is Professor of Clinical Neuroscience and Honorary Consultant in Neurology at the University of Cambridge and Addenbrooke's Hospital. He has held this position since 2000 following an MRC Clinician Scientist Fellowship. His primary affiliations are with the Cambridge Stem Cell Institute and the Department of Clinical Neurosciences at the Cambridge Biomedical Campus. Education includes: BA, Oxford University (1983) MBBS, University of London (1986) MRCP, London (1989) PhD, University of Cambridge (1994) Research focuses on neurodegenerative disorders, particularly Parkinson's (PD) and Huntington's diseases (HD). His work bridges basic science exploring novel therapies and clinical studies defining disease heterogeneity. Key initiatives include: Leading the STEM-PD stem cell trial for PD Coordinating the FELL-HD drug repurposing trial for HD Developing disease subtyping models for targeted therapies Collaborating on human brain development mapping for the Human Cell Atlas Research employs snRNA sequencing, post-mortem tissue analysis, and human fetal tissue studies to understand neurodegeneration and neurodevelopment. Recent publications (2023-2025) demonstrate strong focus on: Translational applications of stem cell therapies for Parkinson's Genetic and biomarker studies of neurodegenerative progression Novel therapeutic mechanisms like noradrenergic modulation Advanced cellular modeling techniques including 3D reprogramming Current funding sources include Medical Research Council, Rosetrees Trust, EU, NIHR, Cure Parkinson's Trust, Novo Nordisk, and Wellcome. Lab members include Shaline Fazal (Research Manager), Xiaoling He (Senior Research Assistant), Saeed Kayhanian (Clinical Research Fellow), and Jana Šebestíková (Postgraduate Student). The lab is based at the John van Geest Centre for Brain Repair.

Jocelyn Côtéمشاهده پروفایل

استاد

• RNA Biology
• Neurodevelopmental Disorders
• Neuromuscular Diseases
• +۳ مورد دیگر

Jocelyn Côté is a Full Professor in the Department of Cellular and Molecular Medicine at the University of Ottawa, holding a concurrent role as Assistant Dean, Research and Special Projects in the Faculty of Medicine. His research focuses on the role of arginine methylation in RNA-binding proteins and its implications in neurodevelopmental disorders, neuromuscular diseases, and cancer. He leads studies on the molecular pathways underlying spinal muscular atrophy, myotonic dystrophy, and cancer progression, with particular emphasis on Tudor domain-containing proteins and PRMT enzymes. Education: B.Sc. Biochemistry (Université de Sherbrooke, 1992), Ph.D. Molecular Biology (Université de Sherbrooke, 1998), Postdoctoral Fellowships at Washington University and McGill. Research interests include: (1) arginine methylation regulation in RNA processing, (2) Tudor domain protein functions in disease, and (3) cancer-related epigenetic pathways. His work integrates cell biology, molecular genetics, and proteomics to identify novel therapeutic targets. Publications emphasize RNA biology and disease mechanisms, with recent work highlighting Staufen1's role in myotonic dystrophy and PRMT7's contribution to breast cancer metastasis. While no awards are explicitly listed, his research has implications for neuromuscular and oncological therapies. He collaborates with the Centre for Neuromuscular Diseases and the uOttawa Brain & Mind Research Institute, advancing translational research in neurodegenerative and neuromuscular disorders.

Mats Küssnerمشاهده پروفایل

پژوهشگر

• Multimodal perception of music
• Music and mental imagery
• 4E music cognition
• +۳ مورد دیگر

Mats Küssner is a Researcher at Humboldt University of Berlin's Department of Musicology, specializing in Transcultural Musicology and Historical Anthropology of Music. Previously, he held a Peter Sowerby Research Associate position at the Royal College of Music in London. He earned his doctorate from King's College London, focusing on cross-modal mappings between sound and visual forms. His work bridges music psychology, cognitive science, and cultural studies, emphasizing how music shapes human thought and emotion through multi-method approaches. Research interests include multimodal perception, music-induced mental imagery, 4E cognition (embodied/embedded/enactive/extended), and performance science. Notable awards include the Aubrey Hickman Award for music psychology research and a teaching excellence award. He teaches courses like 'Diversity in Berlin's Sound Scene' and 'Emotions in Music' at both BA and MA levels. His publications span over 40 peer-reviewed articles across journals like Music & Science , Psychomusicology , and Frontiers in Psychology , with a focus on visual-aural interplay, music cognition disorders (e.g., aphantasia), and cross-cultural performance dynamics. He co-edited the landmark volume Music and Mental Imagery (Routledge, 2022). Recent work explores environmental ecomusicology education and music's role in mitigating social isolation. Küssner leads projects on music-induced emotion prediction using cross-modal correspondences and is part of Berlin's interdisciplinary music psychology scene, collaborating with neuroscientists and cultural anthropologists. His lab employs eye-tracking, EEG, and behavioral experiments to study embodied music cognition processes.

• Neuroscience
• Psychiatry
• Cognitive Neuroscience
• +۳ مورد دیگر

Umit Aydin is a researcher affiliated with the University of Reading. His work focuses on neuroimaging techniques applied to developmental disorders such as ADHD and autism spectrum disorder, as well as epilepsy and sleep deprivation effects. He has contributed to studies using EEG, MEG, and fNIRS technologies to understand brain connectivity, cognitive deficits, and clinical outcomes. His research integrates genetic analyses, signal processing advancements, and multimodal neuroimaging approaches. Key areas of investigation include: Electrophysiological correlates of neuropsychiatric disorders Development of advanced neuroimaging methodologies Integration of EEG/MEG with clinical outcomes

Martha Bagnallمشاهده پروفایل

دانشیار

• Neuroscience
• Neural Circuits
• Postural Control
• +۵ مورد دیگر

Martha Bagnall, PhD is an Associate Professor in the Department of Neuroscience at Washington University School of Medicine in St. Louis. Her research focuses on neural circuits involved in postural control and motor coordination, primarily using zebrafish as a model organism. She leads the Bagnall Lab, which investigates how sensory information about orientation and movement drives appropriate body movements to adjust posture. Education: PhD in Neuroscience, University of California, San Diego (2002-2008) BS in Biology, Yale University, New Haven, CT (1996-2000) Dr. Bagnall's research centers on understanding how the brain processes vestibular information to maintain posture and coordinate movement. Her lab studies the vestibulospinal system of larval zebrafish to determine how sensory signals about head orientation are mapped onto spinal circuitry to drive appropriate behaviors. A key area of investigation is how locomotor planning influences vestibular circuits, with particular interest in cerebellar input to vestibular neurons. Her work takes advantage of the transparency of larval zebrafish to dynamically observe neural development and function. Analysis of Dr. Bagnall's recent publications reveals a strong focus on spinal interneuron diversity and connectivity in motor control. Her research has systematically mapped how different spinal neuron types (V1, V2b, etc.) connect with motor and sensory targets to coordinate locomotion at different speeds. There is a clear progression from basic circuit mapping to understanding how developmental processes shape these circuits, with recent work exploring clonal relationships and Notch signaling in spinal neuron differentiation. Her work bridges fundamental neuroscience with potential applications for understanding vestibular pathologies in humans. Scientific Awards: McKnight Scholar Award (2017) Pew Scholar (2016) Sloan Award (2016) K99/R00 Pathway to Independence Award, NIDCD, NIH (2012) NSF Graduate Research Fellowship (2004-2007) Dr. Bagnall has secured significant research funding, including a $1.9 million R01 grant from the National Institute of Neurological Disorders and Stroke to map neuronal connections in the zebrafish spinal cord. This represents her second R01 grant as a principal investigator. Her research employs a multidisciplinary approach combining electrophysiology, imaging, genetic manipulation, optogenetics, and behavioral analysis. The lab's work on V1 neurons revealed that these inhibitory interneurons form location-dependent connections - interfacing with motor neurons near their cell bodies while synapsing on sensory cells further up the spinal cord. The Bagnall Lab is part of the Neurogenetics & Transcriptomics and Axon Injury & Repair research groups at Washington University. Her team collaborates with the Solnica-Krezel lab to investigate later onset of vestibular dysfunction, taking advantage of large-scale genetic screens to identify gene candidates involved in neurodegeneration. The lab's research has demonstrated high homology between the vestibulospinal postural system of fish and mammals, suggesting translational relevance of their findings.

• Psychiatry
• Neuroscience
• Mental Health Epidemiology
• +۳ مورد دیگر

Andrea Amerio is an Associate Professor at the Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, and Maternal and Child Sciences (DINOGMI) within the School of Medical and Pharmaceutical Sciences at the University of Genoa. His academic activities include teaching in multiple psychiatry-related courses across various degree programs and participating in the Joint Teacher-Student Commission. Current academic rank: Associate Professor Primary institution: University of Genoa Key academic affiliations: Psychiatry, Neuroscience, Rehabilitation Research Focus : Andrea Amerio's recent publications highlight interdisciplinary work at the intersection of psychiatry, neuroscience, and public health. His research explores: Mechanisms linking early-life adversities to epigenetic changes affecting brain development Cognitive-emotional patterns in bipolar disorder Microbial dysbiosis in suicidal behavior Epidemiological trends in late-life suicide Substance use challenges across major psychiatric disorders Contact : andrea.amerio@unige.it

Sandra Schickمشاهده پروفایل

استادیار

• Chromatin Biology
• Epigenetics
• Cancer Biology
• +۳ مورد دیگر

Sandra Schick is a Group Leader at the Institute of Molecular Biology (IMB) in Mainz since 2020 and a Junior Faculty Member at the Max Planck Graduate Center (MPGC) since 2021. Her research focuses on ATP-dependent chromatin remodeling complexes, specifically BAF, and their critical roles in cancer pathogenesis and developmental disorders through regulation of DNA accessibility. Her primary research areas include: Chromatin remodeling mechanisms and epigenetic regulation Structure-function relationships of polymorphic BAF complexes Molecular basis of BAF subunit mutations in human diseases Integration of chromatin dynamics with DNA repair and transcriptional control Analysis of her publication record reveals a consistent trajectory in dissecting BAF complex functionality using multi-omics approaches, with emphasis on synthetic lethality networks in cancer and developmental disease contexts. Her work demonstrates how BAF perturbations immediately alter chromatin architecture, providing mechanistic insights for therapeutic targeting. Dr. Schick leads an active research group at IMB that employs CRISPR/Cas9, targeted protein degradation, single-cell genomics, and advanced imaging to investigate chromatin regulation across model systems. She actively recruits experimental and computational scientists to advance understanding of chromatin-related disease mechanisms and resilience pathways.

Jonathan Savitzمشاهده پروفایل

دانشیار

• Neuroscience
• Immunology
• Psychiatry
• +۹ مورد دیگر

Jonathan Savitz, Ph.D., is an Associate Professor of Community Medicine at The University of Tulsa's Oxley College of Health Sciences and Principal Investigator at the Laureate Institute for Brain Research. His work bridges neuroscience, immunology, and psychiatry to investigate immune dysfunction's role in depression, with a focus on inflammation, adaptive immunity, and herpesvirus interactions. Education: Ph.D. in Molecular Genetics from the University of Cape Town, studying bipolar disorder in South African populations. Research Interests: Psychoneuroimmunology, immunopsychiatry, neuroimaging of depression, and the impact of herpesviruses (particularly CMV) on neuropsychiatric disorders. Article Trends: Recent work examines cortical thinning in adolescents linked to inflammation, concussion-related biomarkers in athletes, CMV's role in neuroinflammation, and computational models for brain geometry. His publications highlight interdisciplinary approaches combining genomics, neuroimaging, and immunology. Labs: Leads the Savitz Laboratory, which employs tools from neuroscience, immunology, and virology.

• Genetics
• Molecular Biology
• Bioinformatics
• +۴ مورد دیگر

Sevinç AKÇAY is a Lecturer at the Department of Molecular Biology and Genetics in the Faculty of Arts and Sciences at Kırşehir Ahi Evran University , Turkey. She holds a PhD (2016) and MSc (2012) in Molecular Biology from the University of Pittsburgh , and a BSc (2008) in Biology from Ankara University . Research Focus: Genetics, Molecular Biology, and Bioinformatics, with emphasis on elastin gene mutations , cancer genomics , and computational disease modeling . Key Projects: Investigated Tiochlorosid and Malathion effects on cancer cell lines; led studies on epigenetic mechanisms and ferroptosis in cancer . Teaching: Offers courses in Genetic Engineering , Epigenetics , and CRISPR Technologies at both undergraduate and graduate levels. Collaborations: Works with international researchers like Zsolt Urban (University of Pittsburgh) and Emine Güven (Düzce University) on computational biology and genetic disorders.

Bernet Elzingaمشاهده پروفایل

استاد

• Stress-related psychopathology
• Trauma and PTSD
• Depression and anxiety disorders
• +۳ مورد دیگر

Prof. Bernet Elzinga is a leading researcher at the Clinical Psychology Department of Leiden University, focusing on trauma's psychological, cognitive, and neurobiological consequences. Her work spans stress-related disorders, depression, PTSD, and intergenerational trauma transmission. Key research themes: Intergenerational stress mechanisms Emotion regulation in BPD DSM-5 PTSD criteria validation Developmental psychopathology Her 2021 study on adolescent-parent perception discrepancies revealed critical insights into youth affective states. The 2018 Dutch CAPS-5 validation established high reliability (ICC=0.98) while refining PTSD factor models. Recent projects like RE-PAIR (2024) on emotional maltreatment neurobiology and BAT (2024) targeting familial anxiety transmission highlight her translational approach. Key findings: Demonstrated superiority of the six-factor Anhedonia PTSD model over DSM-5's four-factor structure. Identified Memory impairment (D1) and Reckless behavior (E2) as low-prevalence symptoms in professional trauma populations. Revealed clinician diagnostic ambiguity in moderate-symptom cases, emphasizing the need for collaborative assessment practices. Academic affiliations Leiden Institute for Brain and Cognition Arq Psychotrauma Expert Group collaborations Foundation Centrum '45 partnerships

• Neurobiology
• Theoretical and Computational Neurobiophysics
• Neurodevelopment
• +۵ مورد دیگر

Pınar ÖZ is an Associate Professor at Uskudar University, Department of Molecular Biology and Genetics, since 2015. Her research spans neurobiology, computational neuroscience, and neurodevelopmental disorders, with a focus on membrane properties, adult neurogenesis, and orexin system dynamics. Boğaziçi University, Institute of Biomedical Engineering (2012–2014) Max Planck Institute for Dynamics and Self-organization (2011–2012) Research Interests: Computational modeling of neuronal excitability Neurodevelopmental disorders, including autism models Role of orexin in sleep deprivation and sensorimotor gating Neuroprotective agents (e.g., zeatin) in ischemic models Evolutionary bioinformatics of neurochemical pathways Applications of agent-based modeling in neurogenesis Recent Trends: Publications from 2015–2025 emphasize interdisciplinary approaches combining in vitro and in vivo models with computational tools to study hippocampal plasticity, neurodegeneration, and pharmacological interventions. Scientific Awards: Georg Christoph Lichtenberg Scholarship (Lower Saxony Ministry of Science and Culture, Germany, 2008–2009) Projects: Investigates personalized drug monitoring, neuroprotective effects of zeatin, orexin system's role in psychosis models, and computational frameworks for neurogenesis. She also supervises graduate theses on topics like neurodevelopmental inhibition networks and age-dependent simulations.

James C. Loمشاهده پروفایل

دانشیار

• Cardiometabolic diseases
• Cardiovascular biology
• Adipose tissue function
• +۳ مورد دیگر

James C. Lo, M.D., Ph.D., is the Rohr Family Clinical Scholar and Associate Professor of Medicine at Weill Cornell Medical College . As a physician-scientist, he directs a basic research laboratory investigating the molecular basis of cardiometabolic diseases. 2023 : Rohr Family Clinical Scholar 2023 : Associate Professor of Medicine, Weill Cornell Medical College 2021 : Assistant Professor of Medicine, Weill Cornell Medical College Education: 2006 - M.D., University of Chicago Pritzker School of Medicine 2004 - Ph.D., University of Chicago 1998 - B.S., University of Chicago Dr. Lo's research focuses on molecular mechanisms of metabolic diseases with emphasis on: Cardiovascular biology in diabetes and obesity Adipose tissue function and thermogenesis Pancreatic islet physiology in metabolic stress Inter-organ communication networks Novel therapeutic targets for diabetes Cardiac complications in metabolic disorders Complement system in endocrine regulation His lab employs single-cell RNA-seq , genetic models , and multi-omics approaches to study: β cell subpopulations in diabetes Complement receptor signaling Adipose-liver-heart cross-talk Extracellular vesicle-mediated dysfunction Sex-dependent metabolic regulation Scientific Contributions: First to identify adipsin's role in β cell protection Discovered complement system's role in islet function Defined adipose tissue as SARS-CoV-2 target Elucidated mechanisms of obesity-induced arrhythmias Developed cross-species models of metabolic stress Research Funding: Currently holds 8 major grants as Principal Investigator or Key Personnel, including: $2.1M - NIH/NHLBI Mechanisms of Obesity-induced Atrial Fibrillation (2025-2028) $2.8M - NIH/NIDDK NAD+ Metabolism in β Cell Dysfunction (2025-2030) $1.5M - AHA Obesity-Driven Atrial Fibrillation (2024-2027) $1.2M - AHA Zebrafish Heart Regeneration (2023-2026) His laboratory team at the Belfer Research Building (New York, NY) includes post-doctoral fellows, Ph.D. students, medical students, and research technicians working in a collaborative environment.

• Acute Lymphoblastic Leukemia
• Pediatric Brain Tumors
• Genetic Heterogeneity
• +۵ مورد دیگر

Stephen E. Sallan, MD , is a Professor of Pediatrics at Harvard Medical School and a Physician at Dana-Farber Cancer Institute and Children's Hospital . His career spans over five decades in pediatric hematology/oncology , with a focus on acute lymphoblastic leukemia (ALL) and pediatric brain tumors . Education : MD, Wayne State University School of Medicine (1967) Residencies : Boston Floating Hospital (1968), Children's Hospital of Philadelphia (1969), Hospital for Sick Children, London (1970) Fellowship : Pediatric Oncology, Children's Hospital/DFCI (1972) Leadership Roles : Chief of Staff (1995), Chairman of Medical Staff Executive Committee (1995), Chief of Staff Emeritus (2012) Dr. Sallan's research integrates genetic heterogeneity , disease recurrence , and drug resistance in ALL, with efforts to develop targeted therapies like tumor vaccines and antiangiogenesis agents. His work addresses long-term treatment toxicities (cardiac, skeletal, neurocognitive), particularly in survivors of childhood cancers. His 15 most recent publications (2024–2018) demonstrate ongoing engagement with pharmacogenomics, thrombosis risk models, dietary interventions, and molecular markers in brain tumors. Key subfields include TRK-C in medulloblastoma , asparaginase complications , and DFCI ALL Consortium Protocols . Scientific Awards : Distinguished Alumni Award, Wayne State University School of Medicine (1997) James Carreras Prize for International Pediatrician of the Year (1987) As a leader in pediatric leukemia research , Dr. Sallan has shaped treatment protocols that minimize late effects while improving survival. He collaborates with multidisciplinary teams in neuro-oncology and pharmacogenomics, maintaining active roles in clinical trials and laboratory investigations.

Martha L. Bulykمشاهده پروفایل

استاد

• Transcription factors
• DNA regulatory elements
• Genomics
• +۵ مورد دیگر

Martha L. Bulyk is a Professor of Medicine and Pathology at Harvard Medical School, with appointments in the Division of Genetics at Brigham & Women's Hospital. She serves as Co-Chair of the Harvard Biophysics Graduate Program and holds associate memberships at the Broad Institute of MIT and Harvard and the Dana-Farber Cancer Institute Center for Cancer Systems Biology. Her laboratory is located in the New Research Building at Harvard Medical School in Boston. Her research focuses on decoding transcriptional regulation through the study of transcription factors (TFs) and DNA regulatory elements. Using integrated experimental and computational genomics approaches, her lab investigates: High-throughput analysis of TF-DNA binding specificities Cis-regulatory codes in eukaryotic genomes Effects of protein interactions and DNA structure on TF function Molecular determinants of protein-DNA binding specificity and evolution Impact of genetic variation on human transcription factors Pioneer factor interactions with nucleosomes Regulatory functions of alternative TF isoforms in breast cancer Quantitative information encoding in transcriptional enhancers/silencers Recent publications demonstrate a strong focus on mechanistic studies of transcriptional regulation, with recurring themes in chromatin dynamics, cancer biology (particularly neuroblastoma and breast cancer), developmental gene regulation, and computational method development. Her work frequently integrates structural, evolutionary, and functional genomics approaches. The Bulyk Laboratory currently comprises 2 graduate students, 3 postdoctoral fellows, 4 technicians, and 2 undergraduate students. The lab participates in multiple Harvard University programs including the Biophysics PhD Program, Biological & Biomedical Sciences (BBS) PhD Program, Systems/Synthetic/Quantitative Biology PhD Program, Bioinformatics & Integrative Genomics (BIG) PhD Program, and the School of Public Health Program in Quantitative Genomics.

Zuzana Storchováمشاهده پروفایل

استاد

• Molecular Genetics
• Chromosome Biology
• Aneuploidy
• +۷ مورد دیگر

Professor Zuzana Storchová is a leading researcher in molecular genetics at Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau (RPTU), Germany, where she has served as Professor of Molecular Genetics in the Department of Biology since 2016. Her research group focuses on understanding how changes in chromosome numbers and structure affect cellular functions, with critical implications for developmental defects and cancer pathologies. Her research program encompasses several key areas of investigation: Chromosomal aberrations and their cellular consequences Impact of chromosome gain on DNA replication and genomic stability Consequences of chromosome loss (monosomy) in human cells Maintenance of protein homeostasis in response to chromosomal imbalance Whole genome doubling and its contribution to genome evolution and cancer development Professor Storchová's laboratory employs cutting-edge technologies including biochemistry, cell biology, and multi-omics approaches to study the molecular processes affected by aneuploidy. They have developed specialized human cell lines with specific chromosomal abnormalities to investigate how cells respond to altered chromosome numbers. Using genomics, transcriptomics and proteomics, her team analyzes genome stability and protein homeostasis in aneuploid cells and elucidates the molecular links to human disease. Her publication record demonstrates a consistent focus on understanding the proteomic consequences of aneuploidy, mechanisms of genomic instability following whole-genome duplication, and therapeutic vulnerabilities of aneuploid cancer cells. Recent work has revealed how missegregation of even a single chromosome strongly affects cellular physiology, with many aneuploid cells failing to proliferate while others develop severe consequences including impaired protein homeostasis and compromised genomic stability. Professor Storchová's research trajectory shows a progression from fundamental chromosome biology to translational cancer research, with her work providing critical insights into how chromosomal abnormalities drive cancer development and identifying potential therapeutic targets for aneuploidy-associated diseases.