معرفی
Roger Barker is Professor of Clinical Neuroscience and Honorary Consultant in Neurology at the University of Cambridge and Addenbrooke's Hospital. He has held this position since 2000 following an MRC Clinician Scientist Fellowship. His primary affiliations are with the Cambridge Stem Cell Institute and the Department of Clinical Neurosciences at the Cambridge Biomedical Campus.
Education includes:
- BA, Oxford University (1983)
- MBBS, University of London (1986)
- MRCP, London (1989)
- PhD, University of Cambridge (1994)
Research focuses on neurodegenerative disorders, particularly Parkinson's (PD) and Huntington's diseases (HD). His work bridges basic science exploring novel therapies and clinical studies defining disease heterogeneity. Key initiatives include:
- Leading the STEM-PD stem cell trial for PD
- Coordinating the FELL-HD drug repurposing trial for HD
- Developing disease subtyping models for targeted therapies
- Collaborating on human brain development mapping for the Human Cell Atlas
Recent publications (2023-2025) demonstrate strong focus on:
- Translational applications of stem cell therapies for Parkinson's
- Genetic and biomarker studies of neurodegenerative progression
- Novel therapeutic mechanisms like noradrenergic modulation
- Advanced cellular modeling techniques including 3D reprogramming
Current funding sources include Medical Research Council, Rosetrees Trust, EU, NIHR, Cure Parkinson's Trust, Novo Nordisk, and Wellcome.
Lab members include Shaline Fazal (Research Manager), Xiaoling He (Senior Research Assistant), Saeed Kayhanian (Clinical Research Fellow), and Jana Šebestíková (Postgraduate Student). The lab is based at the John van Geest Centre for Brain Repair.
