جست‌وجوی استاد و پژوهشگر

• Plant Genetics
• Genomics
• Metabolomics
• +۴ مورد دیگر

Joost Keurentjes is an Associate Professor in the Laboratory of Genetics at the Plant Ecology and Resources Centre (PE&RC), Wageningen University. His research focuses on plant genetics, genomics, and metabolomics, particularly in Arabidopsis. He leads projects on quantitative trait locus (QTL) mapping, epistasis, and environmental stress responses. His work integrates genetic and genomic approaches to understand plant adaptation and complex traits. Education: No explicit educational details provided. Research Interests: Plant genetics, metabolomics, Arabidopsis biology, QTL analysis, epigenetics, and stress responses. Recent studies highlight his work on chromosome substitution mapping, glucosinolate-plant stress associations, and drought tolerance mechanisms. His projects include collaborations on genetic mapping in Brassicaceae and epigenetic regulation of metabolomes. He advises multiple PhD candidates in plant genetics and genomics. Grants & Projects: Active in funding initiatives like 'Accelerating genetic mapping in non-recombinant Brassicaceae genomes' and 'Close-up! A close-up of unresponsive guard cells of plants grown at high humidity.' Labs/Teams: Head of the Laboratory of Genetics (PE&RC), collaborating widely on plant genomics and stress biology.

• Bioinformatics
• Machine Learning
• Network Science
• +۴ مورد دیگر

Anne Hartebrodt is a Postdoctoral Researcher at the Biomedical Network Science Lab in the Department of Artificial Intelligence in Biomedical Engineering at Friedrich-Alexander University Erlangen-Nürnberg (FAU), Germany. She has been working at FAU since March 2023, focusing on network-based embeddings and carbon-aware computing for bioinformatics following her PhD completion at the University of Southern Denmark. Her research spans multiple cutting-edge domains at the intersection of AI and biomedical science: Bioinformatics and computational biology with emphasis on network science Federated learning and privacy-preserving computation for biomedical applications Single-cell omics analysis and gene regulatory network inference Carbon-aware computing for sustainable bioinformatics research Machine learning applications in proteomics and cancer research Dr. Hartebrodt's publication record demonstrates expertise in developing computational methods that bridge theoretical machine learning with practical biomedical challenges, particularly in maintaining data privacy while enabling collaborative research across institutions. Her work on federated learning approaches has been published in high-impact journals including Nature Computational Science and Bioinformatics. Her research leadership includes: Principal investigator for the 'Dimensionality reduction for molecular data based on explanatory power of differential regulatory networks' project (NetMap) funded by the Bundesministerium für Forschung, Technologie und Raumfahrt (2023-2026) Development of FedProt for privacy-preserving protein analysis Creation of Decoil for reconstructing extrachromosomal DNA structures Advancements in federated singular value decomposition methods Dr. Hartebrodt actively supervises multiple graduate students working on gene regulatory networks, differential expression analysis, and carbon-aware optimization. Her laboratory work in the Biomedical Network Science Lab focuses on developing innovative approaches to analyze complex biological networks while addressing computational sustainability through carbon-aware computing methods.

Zhi-Chun Laiمشاهده پروفایل

استاد

• Cell Biology
• Cell Signaling
• Developmental Biology
• +۴ مورد دیگر

Zhi-Chun Lai is a Professor of Biology and Biochemistry and Molecular Biology at Pennsylvania State University, affiliated with the Department of Biology and the Huck Institutes of the Life Sciences. His research focuses on the Hippo signaling pathway, cell growth regulation, and cancer genetics. He holds a Ph.D. from Albert Einstein College of Medicine (1989), an M.S. from the same institution (1985), and a B.S. from Peking University (1982). Postdoctoral training was conducted at the University of California, Berkeley. His research investigates how the Hippo pathway controls tissue growth and organ size through tumor suppressors like Mats and Wts/Lats kinases. Key discoveries include the role of Mats as a coactivator of Wts kinase and its conserved function across species. Collaborations, such as with Dr. K.-L. Guan’s lab at UC San Diego, have advanced understanding of Hippo signaling in mammals, including YAP/Yki’s oncogenic roles. Zebrafish studies further validate Mats’ evolutionary conserved role in growth control. Awards include the Global Classroom Award (2011) and the March of Dimes Basil O’Connor Starter Scholar Award (1996–1998). The Lai Lab employs Drosophila, zebrafish, and mammalian models to study Hippo signaling’s interplay with cancer, development, and cellular processes like apoptosis and N-glycosylation. Current work explores Yap1’s protective roles in beta-cell survival and novel CRISPR-based genome engineering approaches.

Kateryna Makovaمشاهده پروفایل

استاد

• Bioinformatics
• Evolutionary Biology
• Genetics
• +۴ مورد دیگر

Kateryna Makova is a Professor of Biology and Verne M. Willaman Chair of Life Sciences at Pennsylvania State University’s Eberly College of Science. Her research focuses on molecular evolution, population genetics, evolutionary genomics, bioinformatics, and human genetics. She leads the Makova Lab, which investigates male mutation bias, gene expression evolution, and human population genomics. Notable projects include studying mutation rates across chromosomes, mitochondrial mutation dynamics, and non-B DNA structures in ape genomes. Educated at Kiev State University (MS, 1995) and Texas Tech University (PhD, 1999), she completed postdoctoral training at the University of Chicago. Her lab’s work has revealed insights into Y chromosome evolution, mitonuclear interactions, and childhood obesity links to epigenetics. Collaborations include work with the Huck Institutes of the Life Sciences and researchers like Mark Shriver and Evan Eichler. Her lab’s projects include analyzing non-B DNA structures (e.g., G-quadruplexes), regional mutation rate variations, and complete ape genome sequencing. Recent publications highlight rapid Y chromosome evolution and the conservation of X chromosomes. She advises multiple PhD students, including Edmundo Torres-González and Xinru Zhang, and has contributed to groundbreaking genomic assemblies of great ape sex chromosomes. Her research spans from fundamental genomic mechanisms to applied studies, such as linking methylation profiles to childhood obesity. The lab also explores mitochondrial mutations in human oocytes and their lack of age-related increase, challenging prior assumptions. These studies underscore her lab’s interdisciplinary approach to understanding genome dynamics and human health.

Kyriaki Michailidouمشاهده پروفایل

عضو هیئت علمی

• Biostatistics
• Genetic Epidemiology
• Statistical Genetics
• +۴ مورد دیگر

Dr. Kyriaki Michailidou is an Associate Lecturer in Mathematics and Statistics at the University of Central Lancashire Cyprus (UCLan Cyprus) and an Associate Scientist at the Cyprus Institute of Neurology and Genetics (CING). She holds a PhD in Statistical Analyses of Genome-wide Association Studies in Breast Cancer from the University of Cambridge (2015), an MSc in Applied Statistics from the University of Oxford (2009), and a BA in Mathematics from Aristotle University of Thessaloniki (2008). Her research focuses on biostatistics, genetic epidemiology, and statistical genetics, with a particular emphasis on polygenic risk scores, fine-mapping analyses, and variant classification in cancer genes. She has co-authored over 100 publications in high-impact journals, including Nature , Nature Genetics , and Cancer Discovery . Dr. Michailidou has received several awards, including the Panos Ioannou Junior Scientist Award (2019) and the Young Researcher Award in Life Sciences (2018). She leads the Biostatistics and Epidemiology module at UCLan Cyprus and has secured significant research funding, including a €60,000 grant (CULTURE/AWARD-YR/0418/0017) for modified segregation analysis of BRCA1/2 variants. Her work spans collaborations with global consortia such as the Breast Cancer Association Consortium (BCAC) and ENIGMA, focusing on genomic analyses of cancer susceptibility and clinical variant interpretation. She also contributes to diagnostic NGS pipelines and translational genomic research.

John Wernerمشاهده پروفایل

استاد

• Antibiotic Resistance
• Bacteriophage Therapy
• Microbiology
• +۳ مورد دیگر

John Werner is a Biology Professor at Wisconsin Lutheran College (WLC), specializing in microbiology and molecular biology. He holds a B.A. in Biology and Chemistry from Luther College, a Ph.D. in Molecular and Cellular Biology from Arizona State University, and completed postdoctoral research at Princeton University. His research focuses on antibiotic resistance mechanisms, bacteriophage therapy, and novel antimicrobial strategies such as silver nanoparticles and ozone sterilization devices. He advises students on projects involving bacterial efflux pumps, phage therapy, and antimicrobial agents. Werner has led WLC’s iGEM teams to multiple medals, including a Gold Medal in 2015 for Project Tolsee. His scholarly works include studies on bacterial cell division mechanisms, CTP synthase cytoskeletal filaments, and evolutionary genetics related to human amylase. He actively participates in academic service, including roles in the American Society for Microbiology. Teaching responsibilities include courses in Microbiology, Immunology, Genetics, Molecular Biology, and Research Strategies. His research emphasizes practical applications of microbiology, such as detecting contaminants in water and developing alternative antibacterial methods.

• Cell Biology
• Stem Cell Research
• Hematopoiesis
• +۳ مورد دیگر

Elisa Bianchi is Associate Professor of Applied Cell Biology at Unimore's Centre for Regenerative Medicine. Her research deciphers molecular mechanisms in hematopoiesis, with emphasis on myeloproliferative neoplasms (MPNs), stem cell differentiation, and oxidative stress pathways. She has identified key roles for miRNAs, TGF-β signaling, and osteopontin in bone marrow fibrosis. Recent work explores chromosomal abnormalities in JAK2-mutant MPNs and regenerative applications for liver disease. Dr. Bianchi teaches cellular biology and laboratory techniques for biotechnology students. She coordinates research on genomic instability in hematologic malignancies.

• Cancer Biology
• Molecular Oncology
• Genomics
• +۳ مورد دیگر

Takeshi Ito is an Associate Research Scientist in the Department of Medical Oncology and Hematology at Yale School of Medicine. His research focuses on molecular mechanisms underlying cancer metastasis, tumor biology, and therapeutic resistance, with a particular emphasis on cell adhesion molecules (e.g., CADM1, IGSF3) and their roles in cancer progression. He investigates signaling pathways such as Hippo/YAP1 and NFAT, as well as genomic alterations in cancers like lung adenocarcinoma and neuroendocrine carcinomas. His work integrates experimental and computational approaches, including mathematical modeling of drug resistance mechanisms and quantitative analysis of protein interactions. He contributes to translational research through studies on circulating tumor DNA as a biomarker and development of radiolabeled therapeutics. Ito’s research bridges basic science and clinical applications, aiming to improve cancer diagnosis and treatment strategies.

• Cancer Biology
• Receptor Tyrosine Kinase (RTK) Signaling
• Oncogene Addiction
• +۷ مورد دیگر

Andrea Bertotti is a Professor in the Department of Oncology at the University of Turin, Italy. His research focuses on cancer biology, particularly receptor tyrosine kinase (RTK) signaling, oncogene addiction, and targeted therapies. He leads translational studies on metastatic colorectal cancer (CRC), leveraging patient-derived xenograft (PDX) models to predict clinical responses and investigate drug resistance mechanisms. Key contributions include identifying HER2 amplification as a predictive marker for anti-EGFR therapy resistance, now integrated into clinical guidelines. His work emphasizes synthetic lethality strategies, tumor evolution, and drug tolerance. Bertotti coordinates a large PDX platform of over 800 CRC liver metastases, systematically profiled for molecular traits and drug responses. He explores evolutionary properties of tumors, including mutation rates under therapeutic pressure, using patient-derived tumoroids (PDTs) and cell lines. His ERC Consolidator Grant (N°724748) supports investigations into residual disease mechanisms post-EGFR therapy. Academically, Bertotti teaches courses in Molecular Oncology and Precision Medicine. He serves on the Department Council and contributes to academic committees. His research bridges basic science and clinical translation, aiming to advance personalized cancer therapies.

• Genetics
• Genomics
• Neurogenetics
• +۵ مورد دیگر

Dr. Cleo van Diemen is a Research Fellow at the University of Groningen's Faculty of Medical Sciences, specifically affiliated with the Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI). With an active research profile comprising 98 publications, her work focuses on advancing genetic diagnostics and understanding genetic disorders through cutting-edge sequencing technologies. Her research interests span multiple areas of genetics and genomics, with particular emphasis on neurogenetics (especially spinocerebellar ataxia), DNA sequencing methodologies, and genetic diagnostics. She has made significant contributions to understanding repeat expansion disorders, copy number variants, and the application of long-read sequencing technologies in clinical diagnostics. Her work often involves collaborations across multiple Dutch institutions and international research groups. Analysis of her recent publications (2020-2025) reveals a strong trend toward implementing advanced sequencing technologies like Nanopore long-read sequencing for diagnosing neurological disorders, improving variant interpretation pipelines, and exploring genetic underpinnings of rare diseases. Her research bridges basic genomic science with clinical applications, particularly in neurology, prenatal diagnostics, and rare genetic disorders. Dr. van Diemen has contributed to numerous significant findings in genetic diagnostics, including high-impact studies on ataxia genetics, prenatal testing methodologies, and the development of diagnostic pipelines for rare genetic conditions. Her work has been cited extensively across multiple publications. She actively supervises research projects, as indicated by the 'Supervised Work (3)' notation in her profile, and collaborates with various research teams across the University Medical Center Groningen and other institutions. Her laboratory work primarily focuses on applying and refining genomic technologies for improved diagnostic yield in challenging clinical cases.

Soodeh Tirnazمشاهده پروفایل

پژوهشگر ارشد

• Biochemistry
• Genetics
• Molecular Biology
• +۳ مورد دیگر

Soodeh Tirnaz is an Adjunct Research Fellow at the School of Biological Sciences , The University of Western Australia . Her work focuses on plant genetics and genomics, particularly in Brassica species and soybean. Primary Affiliation: School of Biological Sciences, The University of Western Australia Research Interests: Genetics, Molecular Biology, Plant Biotechnology, Agricultural Sciences, Genomics Her recent research explores resistance gene analogues in Brassica rapa and napus, fatty acid biosynthesis in soybean, and the application of crop wild relatives in breeding programs. She contributes to understanding genetic diversity and its application in crop improvement, aligning with UN Sustainable Development Goals for food security and environmental sustainability. Key trends in her publications include pangenomics , abiotic stress adaptation , and genetic variation analysis across plant species. Her datasets on Amborella and Brassicaceae pangenomes are widely used in the scientific community. Collaborations: Regularly works with colleagues like Dr. Jacqueline Batley, Prof. David Edwards, and Dr. Paul E. Bayer on plant genomics and breeding projects.

• Public Health
• Epidemiology
• Genetics
• +۳ مورد دیگر

Dr. Desmond Campbell is a Researcher at the University of Glasgow's MRC/CSO Social and Public Health Sciences Unit, part of the Institute of Health and Wellbeing. His work focuses on investigating health inequalities in employment and mortality outcomes using large datasets such as UK Biobank and advanced methods like Mendelian Randomisation. He employs R for statistical analysis and explores topics including public health, epidemiology, and genetics. Recent publications highlight his contributions to understanding socioeconomic health disparities, biases in administrative data, and causal effects of income on health. His research also extends to genetic studies related to conditions like schizophrenia and ADHD, as well as cardiovascular and renal health. Collaborations involve institutions globally, emphasizing interdisciplinary approaches to public health challenges.

Dineke Verbeekمشاهده پروفایل

دانشیار

• Genetics & Heredity
• Neurosciences
• Medical Education Research
• +۳ مورد دیگر

Dr. Dineke Verbeek is an Associate Professor (Tenure Track) in the Faculty of Medical Sciences at the University of Groningen. She holds an adjunct position as a Rosalind Franklin Fellow and is affiliated with the Biology-Related, Artificial, and Interventional Neuroscience (BRAIN) research group and the Lifelong Learning, Education & Assessment Research Network (LEARN). Her work bridges clinical neurogenetics and medical education, with a focus on rare movement disorders, neurodegenerative diseases, and genetic mechanisms underlying ataxias and dystonias. She leads research into spinocerebellar ataxias, exploring genetic mutations, repeat expansions, and molecular pathways. Additionally, she contributes to advancing medical education through innovative research in pedagogical strategies and assessment methods. Her research portfolio includes studies on the functional genetics of disorders like CANVAS (cerebellar ataxia, neuropathy, and vestibular areflexia syndrome), RFC1 mutations, and prodynorphin-related neurodegeneration. She also investigates cross-disease mechanisms linking depression, Alzheimer’s, and neurodegenerative conditions, emphasizing mitochondrial stress responses and synaptic plasticity roles. Collaborations span clinical genetics, molecular biology, and neuroimaging, with projects involving Dutch patient cohorts and international consortia. Dr. Verbeek’s publications emphasize uncovering novel genetic risk loci, developing diagnostic frameworks for genetic variants of uncertain significance, and advancing therapeutic strategies for neurodegenerative disorders. Her interdisciplinary approach integrates basic science, clinical research, and educational innovation to address complex neurological challenges.

Albert Suurmeijerمشاهده پروفایل

استاد

• Oncology
• Pathology
• Surgical Oncology
• +۳ مورد دیگر

Albert Suurmeijer is a Professor with expertise in oncology, pathology, and molecular biology. His research focuses on tumor classification, molecular mechanisms of cancers, and diagnostic advancements. He has published extensively, with over 221 research outputs, including peer-reviewed articles and conference presentations. Key research interests include fibro-osseous tumors, gastrointestinal stromal tumors, and soft tissue sarcomas. His work integrates molecular techniques like DNA methylation analysis and copy number variation studies to refine tumor classification and diagnostics. Recent articles highlight advancements in molecular pathology, such as the use of DNA methylation for tumor classification and insights into kinase fusion-positive tumors. He has also contributed case reports on unusual conditions like chest wall fibrous dysplasia, emphasizing clinical relevance and diagnostic challenges. Suurmeijer has actively engaged in academic activities, including presentations at major conferences like the United States and Canadian Academy of Pathology (USCAP) and the European Congress of Pathology. He has supervised 9 research works, fostering the next generation of pathologists and oncologists. His contributions align with UN Sustainable Development Goals, particularly in advancing health innovations and improving diagnostic accuracy for global health equity.

• Oncology
• Gastroenterology
• Medical Genetics
• +۳ مورد دیگر

Gürsah Kats-Ugurlu is affiliated with the Faculty of Medical Sciences at the University of Groningen, specifically within the Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI). They hold roles as an Opleider (Educator) and Onderwijscoordinator (Education Coordinator) in the Department of Pathology at UMCG. With a background in MD and PhD studies, their work contributes to UN Sustainable Development Goals related to health and well-being. Research interests focus on gastrointestinal cancers, transplantation medicine, molecular pathology, and chemoradiotherapy outcomes. Key areas include neoplasms, esophageal cancer, and histopathological risk stratification in Crohn's disease. They actively engage in academic presentations and professional organizations such as the European Society of Pathology. Recent studies explore cellular signatures in intestinal grafts, DNA methylation in tumors, and Vedolizumab treatment for allograft enteropathy. Their work is peer-reviewed and published in journals like Annals of Surgery , Genes Chromosomes & Cancer , and Transplantation . Collaborations span international and multi-center cohorts, emphasizing translational research in gastroenterology and oncology. They organize and participate in professional webinars and contribute to molecular diagnostics education.