معرفی
Takeshi Ito is an Associate Research Scientist in the Department of Medical Oncology and Hematology at Yale School of Medicine. His research focuses on molecular mechanisms underlying cancer metastasis, tumor biology, and therapeutic resistance, with a particular emphasis on cell adhesion molecules (e.g., CADM1, IGSF3) and their roles in cancer progression. He investigates signaling pathways such as Hippo/YAP1 and NFAT, as well as genomic alterations in cancers like lung adenocarcinoma and neuroendocrine carcinomas.
His work integrates experimental and computational approaches, including mathematical modeling of drug resistance mechanisms and quantitative analysis of protein interactions. He contributes to translational research through studies on circulating tumor DNA as a biomarker and development of radiolabeled therapeutics. Ito’s research bridges basic science and clinical applications, aiming to improve cancer diagnosis and treatment strategies.
