جست‌وجوی استاد و پژوهشگر

• Multiple Testing
• Gene Expression Data
• Spatial Transcriptomics
• +۲ مورد دیگر

Hyeongseon Jeon is a Tenure-track Assistant Professor and Presidential Frontier Faculty (PFF) in the Department of Mathematics at the University of Houston’s College of Natural Sciences and Mathematics (NSM). He holds a joint appointment in the Department of Health Systems & Population Health Sciences (HSPHS) at the Tilman J. Fertitta Family College of Medicine. His research integrates statistical methodologies with biological applications, focusing on spatial transcriptomics, gene expression analysis, and machine learning for healthcare and environmental data. Jeon’s work addresses challenges in multiple testing, data visualization, and computational tools for high-throughput biological datasets. He collaborates across disciplines to advance understanding in cancer immunology, lung biology, and genetic disease mechanisms. His recent publications emphasize spatial transcriptomics experimental design, CAR T-cell therapy biomarkers, and e-cigarette impact on respiratory health. Key areas of focus include developing statistical frameworks for spatial transcriptomics (e.g., spaDesign, Maple) and analyzing immune responses in cancer patients. His research bridges computational innovation with translational medicine, aiming to improve diagnostic and therapeutic strategies through data-driven approaches. No scientific awards or advising records are explicitly listed in the provided materials. His office is located in PGH 629, and he can be reached via hsjeon@central.uh.edu.

Huaqing Zhaoمشاهده پروفایل

استاد

• Epidemiology
• Biostatistics
• Genetics
• +۳ مورد دیگر

Huaqing Zhao, PhD, MS is a Professor at Temple University's Lewis Katz School of Medicine, affiliated with the Center for Biostatistics and Epidemiology and the Neural Sciences department. His roles include leading biostatistical and epidemiological research in health sciences. Education: PhD in Epidemiology (University of Pennsylvania, 2011), MS in Biostatistics (University of Pennsylvania, 2006), and prior degrees from institutions in China. Research focuses on genetic epidemiology, biostatistical methodologies, and applications in neurosciences. His work spans clinical trials, genomic studies, and disease mechanism investigations. Notable contributions include studies on congenital heart diseases, stroke treatments, and neurodegenerative disorders. Publications highlight interdisciplinary collaboration across genetics, pharmacology, and clinical medicine. Active in professional societies like the International Biometric Society and American Statistical Association.

David S. Roosمشاهده پروفایل

استاد

• Cell and Developmental Biology
• Evolution
• Genetics
• +۴ مورد دیگر

David S. Roos is the E. Otis Kendall Professor of Biology at the University of Pennsylvania's School of Arts & Sciences. He leads research on protozoan parasites, focusing on Toxoplasma and Plasmodium, combining genetics, genomics, and computational biology to study host-pathogen interactions. His work bridges evolutionary biology, cell biology, and drug discovery. Education: Postdoc (Helen Hay Whitney Fdn., Stanford), PhD (Rockefeller University, 1984), AB (Harvard, 1979). Research interests include parasite cell biology, apicoplast function, drug target discovery, and comparative genomics. His lab uses forward/reverse genetics, chemical biology, and bioinformatics. Key tools include oligonucleotide microarrays and CRISPR-based mutagenesis. Scientific contributions span parasite life cycle regulation, immune evasion mechanisms, and genomic resources like EuPathDB. He co-leads international efforts to develop pathogen databases (OrthoMCL, TDR Targets) and trains researchers globally in bioinformatics. Teaching includes courses on biochemistry, infectious disease mechanisms, and parasite biology. Active in developing computational tools for pathogen research and advocating for open-access genomic resources.

• Genetics
• Genomics
• Cancer Genetics
• +۶ مورد دیگر

Nathan D Pankratz is a Professor in the Laboratory Medicine and Pathology department at the University of Minnesota, with expertise in Screening, Prevention, Etiology & Cancer Survivorship . His research focuses on genetic and genomic studies, including genome-wide association analyses, epigenetics, and structural variations in diseases like colorectal cancer and venous thrombosis. Key Research Areas: Genetics, Genomics, Hematology, Oncology, Epidemiology Affiliation: University of Minnesota Recent Publications highlight work on Human Leukocyte Antigen (HLA) typing quality control , CFTR gene variants in colorectal cancer , coagulation factor genetics , and mosaic chromosomal alterations . These studies span Genetics , Molecular Biology , and Public Health applications. Projects & Grants include: Structural Variation and Hematological Traits (PI, NIH funding, 2023–2027) Epidemiology of Venous Thrombosis and Pulmonary Embolism (CoI, NIH funding, 2021–2026) Role of genetic/epigenetic alterations in CFTR and colorectal cancer (CoI, NCI funding, 2021–2024)

• Molecular Genetics
• Viticulture
• Pomology
• +۷ مورد دیگر

Dr. Ulrike Anhalt-Brüderl is a Senior Scientist at the Institute of Viticulture and Pomology, Department of Crop Science, University of Natural Resources and Life Sciences, Vienna (BOKU). She has been in this role since 2009 and is actively engaged in research, teaching, and project leadership in molecular genetics of fruit and grapevine crops. Her research interests lie in molecular genetics, viticulture, pomology, genetic diversity, clonal selection, and molecular markers . She applies advanced genetic tools to study grapevine and fruit tree biodiversity, with a focus on autochthonous and endangered cultivars. Her work supports conservation, cultivar identification, and sustainable breeding. Her recent publications span topics including genetic diversity in pears and cherries, transposable elements in grapevines, clonal variation in Riesling and Pinot Noir, and spectral detection of fungal infections . These reflect a strong trend toward integrating molecular biology with precision agriculture and conservation. Senior Scientist at BOKU since 2009 Project leader of EU-funded conservation initiatives Organizer of professional courses in viticulture Active in knowledge transfer and public outreach She has supervised multiple master’s theses in areas such as phylloxera genetics, molecular characterization of Prunus species, and grapevine disease detection. Her collaborative research includes work with institutions in Croatia, Montenegro, and across Europe. Dr. Anhalt-Brüderl is involved in community services through organizing educational programs and contributing to scientific conferences. Her lab focuses on molecular genotyping platforms and genetic analysis of horticultural crops.

• Fungal Biology
• Pathogenicity
• Host-pathogen interactions
• +۷ مورد دیگر

Christophe D’Enfert is a Professor at Institut Pasteur and Head of the Fungal Biology and Pathogenicity Unit, which operates within the Mycology Department and the Department of Genomes and Genetics. His research focuses on the biology, pathogenicity, and genomics of Candida albicans and other pathogenic yeasts, with a strong emphasis on biofilm formation, morphogenesis, and host-microbiota interactions. He is affiliated with the National Institute for Agronomic Research (INRAE) and collaborates internationally, including with the University of Aberdeen. PhD in Molecular Biology, Institut Pasteur His research interests center on the mechanisms underlying fungal infections, particularly in immunocompromised individuals. He investigates C. albicans genomic diversity, colonization of biotic and abiotic surfaces, and regulation of morphogenesis. His lab uses functional genomics, high-throughput screening, and molecular biology to dissect virulence mechanisms and antifungal resistance. The recent publications reflect a strong trend in understanding fungal cell wall architecture, metabolic adaptation in biofilms, host-fungal-microbiota interplay, and genomic basis of virulence and resistance. His work spans molecular microbiology, systems biology, and translational medical mycology. Coordinator, Marie Sklodowska-Curie Initial Training Network (FunHoMic) Funded by Swiss National Science Foundation (Sinergia program) Christophe D’Enfert leads multiple research grants and mentors several PhD students and postdoctoral researchers. His lab is part of major transversal projects at Institut Pasteur, including INCEPTION, focused on integrative biology and data science. He contributes to educational initiatives such as the MOOC on Medical Mycology and specialized courses in molecular genetics and epigenetics. His team develops advanced genomic tools like the C. albicans ORFeome and barcoded strain collections, fostering collaborative research across Europe. He leads or co-leads multiple ongoing projects including FunHoMic, CANDIHUB, Candida genomic diversity, biofilm colonization, and morphogenesis regulation. His lab, located at 25-28 Rue du Docteur Roux in Paris, is equipped with state-of-the-art instrumentation for microbiology, genomics, and imaging, supporting a multidisciplinary approach to fungal pathogenesis.

Sören Lehmannمشاهده پروفایل

استاد

• Epigenetics
• Acute Myeloid Leukemia (AML)
• Precision Medicine
• +۶ مورد دیگر

Sören Lehmann is a Professor of Hematology at Uppsala University and leads a research group affiliated with Karolinska Institutet's Department of Medicine, Huddinge. His work focuses on acute myeloid leukemia (AML) through translational approaches integrating epigenetics, multiomic data, and drug sensitivity to improve precision medicine. Key collaborations include the Swedish AML Group , Nordic AML Group , and HOVON International Steering Committee . Specialist in Hematology and Internal Medicine PhD from Karolinska Institutet (2002) Postdoc at UCLA (2005-2006) Research spans epigenetic dysregulation in AML, long non-coding RNAs , clonal hematopoiesis , and therapy-related leukemias . His team employs CRISPR-Cas9 for functional validation and single-cell analyses to dissect heterogeneity. Recent projects include FLT3 mutation-targeted immunotherapy and HEAT-AML clinical trials . Publications emphasize multiomic integration for prognostic modeling, epigenetic drug targets , and real-world data applications in AML and APL. Funding includes the Swedish Cancer Foundation , Swedish Research Council , and Knut and Alice Wallenberg Foundation . His group trains PhD students including Elisabetta Cozzi and Louisa Fredrikson , with former members like Anne Neddermeyer . Collaborations span institutions including Uppsala University, Lund University, and RIKEN Institute (Japan).

Lise-Marie Pigneurمشاهده پروفایل

پژوهشگر

• Evolutionary Genetics
• Invasive Species Ecology
• Freshwater Ecology
• +۳ مورد دیگر

Lise-Marie Pigneur is a researcher at the University of Liège specializing in evolutionary genetics and ecology, with a particular focus on invasive species, especially Asian clams (Corbicula spp.). Her work spans freshwater ecosystems, population genetics, and molecular biology, contributing significantly to understanding genetic structures of invasive organisms and their ecological impacts. Her research interests center on evolutionary genetics of invasive species, with particular expertise in androgenetic reproduction mechanisms in Corbicula clams. She investigates genetic mixing among sexual and asexual lineages, biogeographic origins of invasive populations, and horizontal gene transfer phenomena in aquatic organisms. Her work bridges molecular biology with ecological field studies, examining how genetic adaptations enable species to invade new ecosystems. Analysis of her publication record reveals consistent focus on freshwater invasive species genetics, particularly Corbicula clams, with recent work expanding to river basin ecology and microbial communities in freshwater reservoirs. Her research demonstrates strong interdisciplinary connections between evolutionary biology, ecology, and conservation science. Dr. Pigneur has secured research funding as Principal Investigator for projects examining genetic structure of introduced mammals in Western Europe (2012-2015) and previously contributed as Researcher to studies on evolutionary genetics of invasive Asian clams (2006-2011). Her collaborative network spans multiple European institutions, with significant partnerships in mammalogy and freshwater ecology research. She actively participates in academic communities through conferences including the European Congress of Mammalogy, Benelux Congress of Zoology, and specialized symposia on wildlife management. Her research has been featured in media coverage regarding invasive species studies, including work on North American beavers in Western Europe.

Jacob Luberمشاهده پروفایل

استادیار

• Bioinformatics
• Precision Medicine
• Biomedical Informatics
• +۱۶ مورد دیگر

Dr. Jacob Luber is an Assistant Professor in the Department of Computer Science and Engineering at The University of Texas at Arlington, with affiliate appointments in Bioengineering and as a Guest Researcher at the National Cancer Institute (NIH). He directs the Health Data Science Lab and is a CPRIT Scholar in Cancer Research. PhD in Biomedical Informatics from Harvard University B.S. in Computer Science from Trinity University Dr. Luber's research focuses on: Building computational tools for petabyte-scale cancer imaging analysis Developing interpretable Bayesian models for oncology diagnostics Investigating microbiome impacts on cancer immunotherapy Integrating multi-omics data (single cell transcriptomics, spatial proteomics) Creating AI-driven compression/search systems for pathology slides His lab has received $2.25M in grants including CPRIT First Time Faculty Award and UT System Rising STARs Award. Recent publications demonstrate expertise in: Adversarial AI attacks on pathology models Variational autoencoder-based cancer slide compression Microbiome-driven lactate metabolism in athletes T-cell receptor-based tumor response tracking Single-cell immunology of diabetic NOD mice Polygenic risk scores for diverse populations Scientific Awards: CPRIT First Time Faculty Award UT System Rising STARs Award NSF GRFP Fellowship Keystone Symposia Travel Fellowship Function SIG/ISMB Best Poster Mach Research Fellowship Trinity CS Research Awards GCURS Research Talk Advising & Grants: Mentoring 12 active PhD/Master's students while leading a lab funded by $2M+ CPRIT grant and $250k UT STARs award. Current projects include cancer imaging search engines and microbiome-immunotherapy interactions.

Zane Dobeleمشاهده پروفایل

پژوهشگر

• Medical Genetics
• Molecular Genetics
• Genomics
• +۳ مورد دیگر

Zane Dobele is a researcher at Riga Stradins University, Latvia, actively contributing to medical genetics through publications and collaborative projects. His work focuses on identifying genetic variations linked to diseases across oncology, endocrinology, and cardiology. His research spans Medical Genetics, Molecular Genetics, Genomics, Oncology, Endocrinology, and Reproductive Medicine. Key emphases include genetic polymorphisms in chronic lymphocytic leukemia, polycystic ovary syndrome, and cardiac disorders like arrhythmogenic right ventricular cardiomyopathy, utilizing techniques such as exome sequencing and somatic variant detection. Analysis of his 2016-2021 publications reveals consistent focus on characterizing single-nucleotide polymorphisms, indels, and structural variants in patient populations. His work bridges genetic discovery with clinical applications for improved diagnosis and prognosis, particularly in cancer genomics and reproductive medicine. Dobele participated in the RSU-funded project "Characteristics of Genetic Variations Causing Structural Foetal Malformations, Using Deep Phenotyping and Genotyping" (2019-2020), employing exome sequencing to investigate prenatal genetic conditions. He also engaged in collaborative activities like the 2020 conference on genetic variation classification in next-generation sequencing.

Melinda Ashcroftمشاهده پروفایل

پژوهشگر ارشد

• Infectious Disease Epidemiology
• Climate Change and Health
• Microbial Genomics
• +۳ مورد دیگر

Dr. Melinda Ashcroft is a Research Fellow in Infectious Disease Epidemiology (Climate Change) at The University of Queensland's Faculty of Health, Medicine and Behavioural Sciences. Her work focuses on Nontuberculous mycobacteria (NTM) and climate change impacts on infections, with prior experience in microbial genomics at Monash University, the University of Melbourne, and UQ. She holds a PhD in Microbiology from UQ (2019), with research on extraintestinal pathogenic E. coli genomics and epigenomics. Education: Bachelor of Applied Science (Biotechnology/Biochemistry, QUT 2004); Master of Biotechnology (UQ 2013); PhD in Microbiology (UQ 2019). Research Interests: Microbial genomics, antibiotic resistance mechanisms, molecular epidemiology, bacterial pathogenesis, climate change impacts on infectious diseases, and Neisseria gonorrhoeae transmission dynamics. She has contributed to studies on ST131 and ST101 E. coli lineages, gonococcal resistance, and rapid diagnostic methods. Recent work highlights include genomic analyses of E. coli ST1193 (2024), geographical clustering of multidrug-resistant ST131 (2024), and within-host Neisseria gonorrhoeae variation (2020). Awards: None explicitly listed. Supervision: Available for PhD students. Affiliations: Member of ASM, Australian Bioinformatics Society, and Australian Society for Microbiology.

Martin A. Nowakمشاهده پروفایل

استاد

• Evolutionary Dynamics
• Infectious Diseases
• Cancer Genetics
• +۶ مورد دیگر

Martin A. Nowak is a Professor of Mathematics and Biology at Harvard University, holding joint appointments in the Departments of Mathematics and Organismic and Evolutionary Biology. He has been Director of the Program for Evolutionary Dynamics (2003–2020). His research focuses on evolutionary dynamics, including cooperation evolution, virus infection dynamics, cancer genetics, and game theory. Key contributions include mechanisms of HIV disease progression, drug resistance evolution, and cancer driver/passenger mutation analysis. Education: Born in Vienna (1965), he studied Biochemistry and Mathematics at the University of Vienna (Diploma thesis with Peter Schuster; PhD under Karl Sigmund, graduating sub auspiciis praesidentis rei publicae). As an Erwin Schrödinger Scholar at Oxford, he worked with Robert May, becoming a Wellcome Trust Senior Research Fellow (1992) and Professor of Mathematical Biology at Oxford (1997). He joined Harvard in 2003. Research Interests: Mathematical biology, evolutionary game theory, infectious disease dynamics, cancer evolution, indirect reciprocity, and language evolution. He pioneered virus dynamics, mathematical oncology, and evolutionary graph theory, proposing cooperation as a third evolutionary principle beyond mutation and selection. Awards: Weldon Memorial Prize (1996), Akira Okubo Prize (1999), David Starr Jordan Prize (2001), Henry Dale Prize (2003), Fannie Cox Teaching Prize (2016). Honorary doctorates from Alexandru Ioan Cuza University (2010) and Dominican School of Philosophy and Theology (2015). Elected to the Austrian Academy of Sciences (2001). His work spans 500+ papers and 4 books, with major contributions to evolutionary safety of therapies, cancer genomic analyses, and game-theoretic cooperation models. He explores evolutionary mechanisms in healthcare, ecology, and sociocultural systems.

Niloofar Vaghefiمشاهده پروفایل

مدرس ارشد

• Population Genetics
• Genomics
• Plant Pathology
• +۳ مورد دیگر

Niloofar Vaghefi is a Senior Lecturer at the University of Melbourne and an Adjunct Associate Professor at the Centre for Crop Health (CCH), University of Southern Queensland (UniSQ). Her research focuses on Plant Pathology, Population Genetics, Genomics, Mycology, and Crop and Pasture Protection. Professional Memberships: American Phytopathological Society (APS), Australasian Plant Pathology Society (APPS), APPS-Qld Organizing Committee, National Plant Biosecurity Diagnostic Network (NPBDN), Society for Molecular Biology and Evolution (SMBE). Her work investigates fungal and bacterial pathogens affecting legumes (mungbean, chickpea, soybean) and cereals (barley, sorghum). Key studies include Macrophomina species genomics, Curtobacterium flaccumfaciens pv. flaccumfaciens plasmid dynamics, and Cercospora beticola fungicide resistance mechanisms. She employs multi-locus phylogenies, whole-genome sequencing, and GWAS to understand pathogen evolution and disease management. Scientific Awards: Excellence in Early Career Research Award (2019), Publication Awards (2014, 2019), Australian Pathogen Bioinformatics Symposium Student Award (2014), Alton Gould Edmonds Travel Scholarship (2014).

• Immunology
• Virology
• HIV Research
• +۳ مورد دیگر

Sarah Rowland-Jones is Professor of Immunology at the Nuffield Department of Medicine, University of Oxford, where she leads a research group focused on viral immunity and HIV pathogenesis. Her work integrates laboratory immunology with clinical cohorts across sub-Saharan Africa, China, and the UK to investigate mechanisms of viral control and disease progression. Her primary research examines immune correlates of protection against HIV infection, with specialized projects on pediatric HIV outcomes in Kenya, long-term HIV-1 infection in Zimbabwean adolescents, and HIV-2 non-progressors in West Africa. She investigates how host genetics, T-cell responses, and viral evolution interact to determine clinical outcomes, particularly in resource-limited settings where HIV burden is highest. Her group also studies comorbidities like chronic lung disease and bone health in HIV-infected children. Analysis of her 15 most recent publications (2021-2024) reveals three dominant research trajectories: 1) HIV pathogenesis in pediatric and adolescent populations across Africa, 2) cross-reactive immunity between HIV and SARS-CoV-2, and 3) biomarker discovery for HIV-associated comorbidities. Her work consistently bridges basic immunology with clinical epidemiology, emphasizing translational applications for vaccine design and health equity. Professor Rowland-Jones directs the VITALITY Trial and maintains extensive global health partnerships, including collaborations with Kenyan, Zimbabwean, and Chinese research teams. Her laboratory leverages field-based cohort studies with advanced immunological assays to address critical gaps in HIV management, particularly for vulnerable populations in developing regions. She actively contributes to public discourse through podcasts on HIV and children in Africa.

Brian Huntlyمشاهده پروفایل

استاد

• Leukaemia Stem Cell Biology
• Leukaemogenesis
• Transcriptional and Epigenetic Alterations
• +۳ مورد دیگر

Professor Brian Huntly is a clinical research scientist at the University of Cambridge , leading the Department of Haematology and conducting research at the Cambridge Stem Cell Institute . As a Consultant Haematologist at Addenbrooke’s Hospital, he bridges clinical practice with fundamental research in leukaemia stem cell biology and malignant haematopoiesis . MD from University of Edinburgh PhD in Cambridge Postdoctoral training at Harvard Fellow of Royal College of Pathologists Member of Royal College of Physicians Chair of EHA Fellowships and Grants Committee His research explores how transcriptional and epigenetic alterations drive acute myeloid leukaemia (AML) and malignant lymphomas , with a focus on: Chromatin remodeling Enhancer dysfunction Cancer stem cell dependencies Metabolic vulnerabilities Therapeutic target discovery Mutation-specific disease mechanisms Recent publications highlight: 2025: BET inhibitor resistance mechanisms 2024: CREBBP inactivation in ALL 2024: BCR::ABL1 variant analysis 2023: Chromatin factor screening 2022: UTX/KDM6a tumor suppression Scientific awards and grants include: EHA-José Carreras Young Investigator Award AstraZeneca research funding Cancer Research UK European Hematology Association European Research Council Kay Kendall Leukaemia Fund Wellcome Trust Key collaborations with George Vassiliou and Tony Kouzarides have led to breakthroughs in AML epigenetics and BET protein inhibitors . His group maintains laboratory facilities at the Jeffrey Cheah Biomedical Centre on Cambridge Biomedical Campus. Students and researchers in his group investigate: Leukaemia initiation mechanisms Epigenetic priming Metabolic dependencies DNA repair vulnerabilities Chromatin organization Stem cell fate transitions