Jacob Luber

Dr. Jacob Luber is an Assistant Professor in the Department of Computer Science and Engineering at The University of Texas at Arlington, with affiliate appointments in Bioengineering and as a Guest Researcher at the National Cancer Institute (NIH). He directs the Health Data Science Lab and is a CPRIT Scholar in Cancer Research.

• PhD in Biomedical Informatics from Harvard University
• B.S. in Computer Science from Trinity University

Dr. Luber's research focuses on:

• Building computational tools for petabyte-scale cancer imaging analysis
• Developing interpretable Bayesian models for oncology diagnostics
• Investigating microbiome impacts on cancer immunotherapy
• Integrating multi-omics data (single cell transcriptomics, spatial proteomics)
• Creating AI-driven compression/search systems for pathology slides

His lab has received $2.25M in grants including CPRIT First Time Faculty Award and UT System Rising STARs Award. Recent publications demonstrate expertise in:

• Adversarial AI attacks on pathology models
• Variational autoencoder-based cancer slide compression
• Microbiome-driven lactate metabolism in athletes
• T-cell receptor-based tumor response tracking
• Single-cell immunology of diabetic NOD mice
• Polygenic risk scores for diverse populations

Scientific Awards:

• CPRIT First Time Faculty Award
• UT System Rising STARs Award
• NSF GRFP Fellowship
• Keystone Symposia Travel Fellowship
• Function SIG/ISMB Best Poster
• Mach Research Fellowship
• Trinity CS Research Awards
• GCURS Research Talk

Advising & Grants: Mentoring 12 active PhD/Master's students while leading a lab funded by $2M+ CPRIT grant and $250k UT STARs award. Current projects include cancer imaging search engines and microbiome-immunotherapy interactions.