جستجوی استاد راهنمای دانشگاهی

• Post-translational modification
• Phosphorylation
• SUMOylation
• +۳ مورد دیگر

Dr. Prakash Bhagat serves as an Academic Visitor in the Department of Biosciences at Durham University. He collaborates extensively with Prof. Ari Sadanandom and has previously worked on the FRASS project alongside Dr. Elaine Fitches and FRASS Industries. He holds a PhD from the National Institute of Plant Genome Research, Jawaharlal Nehru University (JNU), New Delhi (2019), where he studied MAPK signaling in plant growth. His postgraduate research at the University of Lucknow focused on plant defense mechanisms involving peroxidases. His research interests center on post-translational modifications such as SUMOylation and phosphorylation, exploring their roles in plant responses to environmental stimuli. Key areas include epigenetic regulation, plant hormone biology (ABA and auxin), and biotechnological applications of molecular insights. Dr. Bhagat’s recent studies emphasize the interplay between SUMOylation and temperature sensing in plants, as well as light-mediated developmental pathways. His work bridges fundamental research and applied plant science, addressing challenges in crop resilience and growth regulation. Awards: Best Flash Talk award at International Symposium on Plant Photobiology 2024 Best Poster Award at Research Away Day 2024 His research has been supported through collaborative projects like the FRASS initiative. While his profile does not explicitly mention student advisement, his contributions to miRNA biogenesis and stress response studies reflect active engagement in molecular plant biology research. He is affiliated with Prof. Ari Sadanandom’s lab and has participated in interdisciplinary teams focusing on plant signaling mechanisms.

Blair Strangمشاهده پروفایل

مدرس

• Virology
• Antiviral Therapeutics
• Human Cytomegalovirus (HCMV)
• +۶ مورد دیگر

Dr. Blair Strang is a Lecturer in Virology at St George's, University of London, where he has worked since 2013. His research focuses on human cytomegalovirus (HCMV) replication and pathogenesis, with an emphasis on developing antiviral therapeutics. University of Glasgow (BSc, 1995-1999) University College London (PhD, 1999-2003) MRC Virology Unit (Postdoc, 2003-2006) Harvard Medical School (Postdoc, 2006-2013) Dr. Strang's research includes high-throughput screening for antiviral compounds, machine learning applications in drug discovery, and investigating host cell proteins as HCMV drug targets. His work extends to DNA virus infections in placental tissue and clinical studies on HCMV shedding during pregnancy. He collaborates with researchers from institutions including Harvard Medical School, University College London, King's College London, and biotech companies like Merck and LifeArc. Funding sources include Medical Research Council (MRC), National Institutes of Health (NIH), Wellcome Trust, and industry partners. Supervises PhD, MRes, MSci, and BSc/iBSc students Teaches virology to MPharm and other advanced students Administers Infection & Immunity research projects Lectures at SGUL Summer School since 2018

• RNA splicing regulation
• Alternative splicing mechanisms
• RNA metabolism in mammalian cells
• +۳ مورد دیگر

Douglas Lyne Black is a Professor in the Department of Molecular, Cell and Developmental Biology (MIMG) at the University of California, Los Angeles (UCLA), affiliated with the School of Medicine. He holds a BA in Chemistry from the University of California, Santa Cruz (1982) and a PhD in Molecular Biophysics and Biochemistry from Yale University (1987). His research focuses on RNA splicing regulation and its role in cellular differentiation, disease, and gene expression. Dr. Black's work explores how alternative splicing contributes to neuronal diversity and dysfunction in cancer, neurodegeneration, and inherited disorders. His research is supported by multiple NIH grants, including principal investigator roles on projects studying PTB and Rbfox proteins' roles in gene regulation (R35GM136426), Myc-driven splicing in prostate cancer (R01CA220238), and sexually dimorphic splicing in the brain (R01MH109166). Collaborative work includes ribonomic studies of innate immune responses (U01HG007912) and genomic splicing measurements (R24GM070857). Key research interests include RNA metabolism, RNA-binding protein structures, and posttranscriptional regulation in neurons. His lab investigates how splicing regulators like PTB, Rbfox, and XIST influence gene expression programs, with applications to human health. Notable contributions include discoveries on splicing mechanisms in cancer, neurobiology, and stem cell differentiation.

Tamer I Sallamمشاهده پروفایل

دانشیار

• Cardiometabolic disease
• Atherosclerosis
• Long non-coding RNAs
• +۷ مورد دیگر

Tamer I Sallam is an Associate Professor of Medicine and Physiology at the University of California Los Angeles (UCLA), where he also serves as the Department Vice Chair for the Medicine Department. His research focuses on the molecular mechanisms underlying cardiometabolic diseases, with particular emphasis on the role of non-coding RNAs and RNA modifications in atherosclerosis, lipid metabolism, and obesity. Dr. Sallam's research interests span multiple interconnected fields in cardiovascular and metabolic biology. He investigates how long non-coding RNAs regulate cholesterol metabolism and atherosclerosis development, with recent work focusing on RNA modification (specifically N6-methyladenosine) and its role in sex-dimorphic metabolic traits. His laboratory also explores the molecular pathways connecting obesity, inflammation, and cardiovascular disease, with implications for therapeutic interventions in metabolic syndrome and related conditions. His work bridges basic molecular mechanisms with translational applications, particularly in understanding sex differences in cardiometabolic disease and developing novel therapeutic approaches. Analysis of Dr. Sallam's publication record reveals a strong focus on the intersection of RNA biology and cardiovascular metabolism. His work demonstrates how epitranscriptomic modifications influence sex-specific metabolic regulation, how long non-coding RNAs modulate lipid homeostasis, and how these mechanisms contribute to atherosclerosis development. His research spans from fundamental molecular mechanisms to clinical implications, with particular attention to sex differences in cardiometabolic disease. Dr. Sallam has secured significant research funding as Principal Investigator on multiple NIH grants, including R01 awards for studying RNA modification in cardiometabolic disease (R01DK127232, 2021-2026), LncRNAs in atherosclerosis (R01HL149766, 2020-2024), non-coding RNAs in adipogenesis and obesity (R01DK118086, 2018-2023), and RNA-binding proteins in atherosclerosis (R01HL139549, 2018-2023). He previously held a K08 career development award focused on long non-coding RNAs in cardiometabolic disease (K08HL128822, 2015-2021). His research is conducted within the Department of Medicine at UCLA, where he leads a laboratory investigating the molecular mechanisms of cardiovascular and metabolic diseases.

• Cancer Biology
• Glucose Metabolism
• Epigenetics
• +۳ مورد دیگر

Claudio Scafoglio is an Adjunct Associate Professor in the School of Medicine at the University of California Los Angeles (UCLA). His research focuses on cancer metabolism, particularly the role of glucose transporters and epigenetic regulation in lung adenocarcinoma. He employs molecular and imaging techniques to identify diagnostic biomarkers and therapeutic targets. Education: MD in Molecular Pathology, Seconda Università degli Studi di Napoli (2002) PhD in Oncology, Seconda Università degli Studi di Napoli (2006) Research Interests: Dr. Scafoglio investigates metabolic reprogramming in cancer, with emphasis on sodium-glucose transporters (SGLTs), glucose deprivation effects, and epigenetic modifications. His work bridges molecular biology, oncology, and translational medicine to develop strategies for early cancer detection and therapy. Publication Trends: His recent articles (2018–2025) focus on SGLT2 inhibitors, metabolic vulnerabilities in lung cancer, and genotoxic-immune interactions. Earlier work (2006–2015) explores transcriptional regulation, DNA damage response, and developmental biology, reflecting a shift toward clinical oncology.

• Fungal Genomics
• Epigenomics
• Genome Instability
• +۴ مورد دیگر

Mareike Moeller is affiliated with the Division of Plant Sciences at The Australian National University. Her research focuses on fungal genomics, epigenomics, and genome instability, particularly in organisms like Zymoseptoria tritici . She holds a PhD in Fungal Genomics and Epigenomics from Kiel University (2014–2018) and has held postdoctoral roles at Oregon State University and Kiel University. Her work explores chromatin dynamics, heterochromatin formation, and the genetic mechanisms underlying genome instability in fungi. Research interests include: Molecular mechanisms of genome instability Epigenetic regulation in pathogenic fungi Role of chromatin modifications in fungal pathogenesis Her publications emphasize interdisciplinary approaches combining genomics and molecular biology to address fundamental questions in fungal biology. She is currently leading a project investigating evolutionary consequences of genome copy maintenance in separate nuclei. Registered to supervise students in plant sciences and related fields.

Michelle Mondouxمشاهده پروفایل

دانشیار

• Cellular and Molecular Biology
• Energy Homeostasis
• Glucose Stress Response
• +۴ مورد دیگر

Michelle Mondoux is an Associate Professor in the Department of Biology and Neuroscience at the College of the Holy Cross. She holds a Ph.D. from Princeton University. Her research focuses on understanding cellular and genetic responses to glucose stress in Caenorhabditis elegans , particularly how excess glucose impacts fertility, lifespan, and intergenerational effects. Her lab explores insulin signaling pathways and O-GlcNAc modification mechanisms. She has contributed to studies linking glucose stress to aging and immunity, identifying key genes like ogt-1 and oga-1 . Dr. Mondoux also develops integrative STEM education strategies, emphasizing interdisciplinary learning in undergraduate neuroscience and biology courses. Her work bridges molecular biology with pedagogical innovation. Research projects include unbiased genetic screens to identify novel genes connecting insulin signaling and glucose stress, with over 100 candidates identified. Her publications span from 2022 to 2007, covering metabolism, aging, and educational methodologies. Collaborations involve molecular biology, genetics, and systems biology approaches to unravel metabolic stress responses in model organisms. She actively engages in curriculum design to enhance student engagement in lab environments, comparing live and virtual learning outcomes.

Srinivas Somarowthuمشاهده پروفایل

دانشیار

• Long non-coding RNAs
• Non-coding RNAs in viral genomes
• RNA-protein complexes
• +۴ مورد دیگر

Srinivas Somarowthu is an Associate Professor in the Department of Biochemistry & Molecular Biology at Drexel University College of Medicine. He serves as Director of the Biochemistry of Health and Disease graduate program, leading interdisciplinary research that combines biochemistry , molecular biology , and computational biology to study RNA mechanisms in cellular pathways. Postdoctoral Fellowship – Yale University (2016) PhD – Northeastern University (2011) MS – Indian Institute of Technology Delhi (2007) BS – Andhra Loyola College (2005) His research focuses on long non-coding RNAs (lncRNAs) and viral non-coding RNAs , particularly their roles in gene regulation, disease mechanisms, and RNA-protein interactions. His lab develops computational tools for modeling large RNA (>200 nts) structures, addressing limitations in experimental RNA structure determination. Recent publications highlight his group's work on structural characterization of lncRNAs like HOTAIR and lncTCF7 , RNA modeling pipelines, and viral RNA-host protein interactions. Notably, his lab received a 2023 CURE Program grant from the Commonwealth of Pennsylvania for hepatitis B virus research. Scientific Awards Commonwealth Universal Research Enhancement (CURE) Program Grant Recipient (2023) His laboratory provides critical resources for RNA structural analysis through webservers and plugins, while collaborating with investigators like Michael J. Bouchard and Joris Beld on liver cancer studies involving Fam99 gene family regulation.

Nan Yangمشاهده پروفایل

دانشیار

• Neuroscience
• Neurodevelopmental Disorders
• Neuroepigenetics
• +۳ مورد دیگر

Nan Yang is an Associate Professor in the Department of Neuroscience at the Icahn School of Medicine at Mount Sinai. Her research focuses on understanding neural development, neuroepigenetics, and the application of stem cell technologies to model psychiatric and neurological disorders. She leads the Yang Lab, which investigates cell fate specification, chromatin modifications in psychiatric diseases, and the use of 3D brain organoids for disease modeling. Yang holds a PhD from Fudan University and completed postdoctoral training at Stanford University. She has been recognized with the 2014 NARSAD Young Investigator Award. Her work integrates stem cell biology, CRISPR gene editing, and single-cell sequencing to uncover molecular mechanisms underlying brain disorders. The lab is actively recruiting postdocs and graduate students. Yang’s research is supported by collaborations with the Seaver Autism Center and includes projects on neurodevelopmental disorders, epigenetic regulation, and translational therapies. Education: Exchange student at University of California, San Francisco; PhD, Fudan University; Postdoctoral training at Stanford University. Research Interests: Human pluripotent stem cells, neurodevelopmental disorders, autism spectrum disorder (ASD), chromatin modifications, brain organoids, CRISPR-mediated epigenetic editing, single-cell sequencing, and translational neuroscience. Notable Achievements: Pioneered transcription factor-mediated neuronal reprogramming, developed models for psychiatric disease using iPSCs, and contributed to understanding epigenetic mechanisms in non-coding genetic variants. Current projects include studying synaptic functions in autism and developing high-throughput in vitro systems for disease investigation. Lab Team: Includes graduate students, postdocs, and research associates focusing on stem cell modeling, neuroepigenetics, and clinical translation. Notable alumni have moved to roles in industry and academia. Lab Locations: Icahn (East) Building, New York, NY. Contact: nan.yang1@mssm.edu or (212) 659-8288.

Julia J. Unternaehrerمشاهده پروفایل

دانشیار

• Cancer Biology
• Stem Cell Biology
• Developmental Biology
• +۵ مورد دیگر

Julia J. Unternaehrer, PhD, is an Associate Professor in the School of Medicine at Loma Linda University, holding joint appointments in Basic Sciences (Biochemistry Division) and Gynecology & Obstetrics. She serves as Vice Chair of Basic Sciences, Co-Program Director for the Cancer, Developmental & Regenerative Biology Program, and directs the Flow Cytometry and Patient-Derived Xenograft Core Facilities. Her research focuses on epithelial-mesenchymal transition (EMT), microRNA regulation, and cancer stem cells, particularly in ovarian cancer progression and therapy resistance. She completed her PhD in Immunology at Yale University and postdoctoral training in stem cell biology at Harvard Medical School. Education: PhD, Yale University, 2004 Master of Philosophy, Yale University, 2004 Bachelor of Science, Loma Linda University, 1987 Research Interests: Dr. Unternaehrer investigates the interplay between EMT factors (e.g., Snail) and microRNAs (e.g., let-7) in cancer development and metastasis. Her lab uses ovarian cancer models to study stemness, drug resistance mechanisms, and therapeutic strategies targeting EMT pathways. Key Themes in Publications: Recent work emphasizes microRNA regulation in cancer aggressiveness, radiation therapy outcomes, and health disparities in ovarian cancer care. Her studies highlight let-7's role as a tumor suppressor and Snail's dual function in reprogramming and oncogenesis. Awards & Grants: Dr. Unternaehrer has secured NIH-funded grants and foundation support for projects like reversing chemoresistance in ovarian cancer and improving BRCA testing rates in Latina populations. She leads initiatives in translational cancer research and precision medicine. Labs & Teams: Directs core facilities supporting flow cytometry and patient-derived xenograft models. Collaborates with multidisciplinary teams in oncology, stem cell biology, and developmental biology.

• Chromosome Dynamics
• Epigenetics
• Genomic Instability
• +۳ مورد دیگر

Dr. Mathew J. Thayer is a Professor in the Department of Biochemistry and Molecular Biology at the University of Southern California, specializing in chromosome dynamics and epigenetic regulation. His research focuses on replication timing control, non-coding RNA interactions, and genomic stability mechanisms. California State University, Chico (BA: Microbiology & Chemistry, 1982) University of Southern California (PhD: Microbiology, 1988; Advisor: Dr. R.E.K. Fournier) Dr. Thayer's work has pioneered understanding of cis-acting elements that regulate DNA replication timing and chromosomal stability. He discovered ASAR lncRNA genes controlling replication patterns and identified chromosome-wide instability mechanisms linked to cancer. His recent publications demonstrate how heterogeneous nuclear ribonucleoproteins interact with ASAR RNAs to orchestrate replication timing, with implications for epigenetic inheritance and cancer genome evolution . Collaborations span cancer biology, developmental genetics, and chromatin research fields. Scientific recognition includes: John A. Resko Faculty Research Achievement and Mentoring Award (2017) Dr. Thayer has contributed to training students through publications and collaborative research, with ongoing work exploring RNA-based chromatin regulation and its role in disease states.

Henning D. Mootzمشاهده پروفایل

استاد

• Protein Chemistry
• Biotechnology
• Nonribosomal Peptides
• +۵ مورد دیگر

Henning D. Mootz is a Professor of Biochemistry and Biotechnology at the Institute of Biochemistry, University of Münster. His research focuses on protein chemistry and biotechnology, particularly protein engineering using split inteins and studying posttranslational modifications like ubiquitination and SUMOylation. He has made significant contributions to understanding nonribosomal peptide synthetases and their dynamics, as well as developing tools for site-specific protein modification. Education: Ph.D. (1999) and postdoctoral training at the Philipps-University of Marburg and Rockefeller University. Awards include the Emmy Noether grant (2003) and teaching awards from the Universities of Münster and Dortmund. Research interests span protein engineering, enzyme mechanisms, and applications in biomedicine. His lab has pioneered methods like photoactivatable inteins for controlled protein splicing and light-activatable antibodies (Photobodies). Over 120+ publications highlight his work in Angewandte Chemie, Nature Chemistry, and other top journals.

Gilles Charvinمشاهده پروفایل

پژوهشگر

• Cell Biology
• Genetics
• Aging
• +۶ مورد دیگر

Gilles Charvin is a Researcher at the University of Strasbourg, leading the Quantitative Biology of Cell Growth team within the Molecular Genetics, Genomics, and Microbiology (GMGM) department under the Faculty of Life Sciences. His work focuses on fundamental cellular processes regulating growth, stress adaptation, and replicative senescence using yeast as a model organism.

• Plant Physiology
• Epigenetics
• Tree Development
• +۴ مورد دیگر

Dr. MARCOS VIEJO SOMOANO is a **Professor** at the **Department of Functional Biology**, part of the **Faculty of Pharmacy** at the **University of Santiago de Compostela**. His research focuses on **Plant Physiology**, particularly **epigenetic regulation mechanisms** in trees, with emphasis on conifers like Norway spruce and chestnut species. He holds a PhD from the University of Oviedo (2015), where his thesis explored epigenetic regulation in European chestnut embryogenesis under Dr. María Jesús Cañal Villanueva and Dr. Peter E. Toorop. His work investigates how environmental stresses (temperature, light, and climate) induce **epigenetic memory** in plants, influencing traits like bud phenology and stress resilience. He leads the **BIOTEC (Biotechnology Research Group)**, focusing on molecular mechanisms underlying plant development and conservation biology. Key methodologies include transcriptomics, DNA methylation analysis, and small RNA profiling. Major research trends in his articles include **DNA methylation dynamics**, **non-coding RNA roles**, and **transgenerational stress memory** in long-lived tree species. His studies bridge basic epigenetic mechanisms with applied forestry and conservation challenges. No awards or grants are explicitly noted in the provided text.

• RNA Interference
• Antisense Oligonucleotides
• Gene Regulation
• +۴ مورد دیگر

Dr. David R. Corey is a Professor in the Department of Pharmacology and Biochemistry at the University of Texas Southwestern Medical Center. He holds a BA in Chemistry from Harvard University and a PhD in Chemistry from the University of California at Berkeley, with postdoctoral training in Pharmaceutical Chemistry at University of California at San Francisco (1990-1992). Education: BA in Chemistry from Harvard (1985), PhD in Chemistry from UC Berkeley (1990). Academic Appointments: Joined UT Southwestern as Assistant Professor (1992), promoted to Associate (2003) and Full Professor (2003) in Pharmacology; secondary appointment in Biochemistry since 1996. Dr. Corey’s research focuses on RNA interference (RNAi), antisense oligonucleotides, and nucleic acid therapeutics. His work spans gene regulation, neurodegenerative diseases (e.g., spinal muscular atrophy, Friedreich’s ataxia, Fuchs’ dystrophy), and molecular mechanisms of miRNA and gene expression modulation. Recent studies highlight nuclear RNAi applications, chromatin-associated RNA targeting, and therapeutic strategies for repeat expansion disorders. Analysis of his publications reveals trends in RNA-based therapies, including allele-selective inhibition , non-coding RNA targets , and delivery optimization to tissues like the cornea and nervous system. Key challenges addressed include miRNA-guided silencing, R-loop dynamics, and translating oligonucleotide activation from cell culture to animal models.