جست‌وجوی استاد و پژوهشگر

• Mitochondrial Diseases
• Neurodegenerative Disorders
• Neuropathology
• +۳ مورد دیگر

Nichola Lax is a Research Fellow at Newcastle University specializing in the neuropathological mechanisms of mitochondrial disorders. Her work focuses on neurological manifestations including Alpers' syndrome, epilepsy, and Lewy body dementia, with extensive collaboration with leading mitochondrial researchers such as Emeritus Professor Doug Turnbull and Professor Robert Taylor. Her research interests include: Mitochondrial Diseases Neurodegenerative Disorders Neuropathology Epilepsy mechanisms Lewy Body Dementia pathology Mitochondrial DNA mutation effects Analysis of her 2016-2023 publications reveals consistent investigation of mitochondrial dysfunction in neurodegeneration, particularly emphasizing astrocytic pathology, respiratory chain defects in specific neuronal populations (inhibitory interneurons, Purkinje cells), and seizure generation mechanisms. Her work employs advanced techniques including multiplex immunofluorescence, CLARITY tissue clearing, and in vitro seizure modeling to establish pathological correlations between mitochondrial defects and clinical phenotypes. No information was found regarding scientific awards, student advising, research grants, or laboratory infrastructure in the provided text.

Shin Kangمشاهده پروفایل

دانشیار

• Glial Biology
• Neural Regeneration
• CNS Diseases
• +۵ مورد دیگر

Shin Kang, PhD is an Associate Professor at Temple University's Lewis Katz School of Medicine in the Department of Neural Sciences and the Center for Neural Development and Repair. His academic appointments reflect a dual commitment to both foundational neuroscience research and translational applications in neural repair mechanisms. Lewis Katz School of Medicine, Temple University Department of Neural Sciences Center for Neural Development and Repair Dr. Kang received his educational training through a rigorous neuroscience pathway: completing his PhD and Postdoctoral Fellowship in the Solomon H. Snyder Department of Neuroscience at Johns Hopkins University School of Medicine, preceded by a Master's in Molecular Biology and Bachelor's in Zoology from Seoul National University. This strong foundation in both basic science and specialized neuroscience prepared him for his current research focus. His research program centers on glial progenitor biology and oligodendrocyte abnormalities in CNS diseases , investigating cellular and molecular mechanisms underlying regenerative glial responses to central nervous system injury. Dr. Kang's laboratory explores how glial cells - particularly oligodendrocyte progenitors that behave like stem cells - contribute to CNS repair through proliferation, differentiation, and direct monitoring of neuronal activity via synapse formation. His work reveals critical neuron-glia signaling mechanisms that regulate regenerative behaviors in health and disease, with implications for numerous neurological disorders where progenitor-derived regeneration becomes misregulated. Analysis of Dr. Kang's publication record reveals a consistent focus on oligodendrocyte biology , neural regeneration , and CNS injury mechanisms over two decades. His research spans from fundamental cellular mechanisms to disease applications, particularly in amyotrophic lateral sclerosis and spinal cord injury contexts. The methodologies employed demonstrate technical sophistication including BAC transgenesis, in vivo cell fate tracing, cell-type specific functional manipulation, and molecular expression profiling in relevant mouse disease models. While no specific scientific awards are listed in the available documentation, Dr. Kang's research program represents a significant contribution to the field of neural repair mechanisms. His work has been published in high-impact journals including Nature Neuroscience, Cell Reports, and Journal of Neuroscience, indicating peer recognition of his scientific contributions. Dr. Kang's laboratory employs diverse molecular and genetic approaches to investigate regenerative mechanisms, utilizing mouse disease models to bridge basic science with potential therapeutic applications. His research program appears well-integrated within the neuroscience community, with frequent collaborations evident in his publication record, particularly with the Bergles laboratory at Johns Hopkins University.

Stefanos Stagkourakisمشاهده پروفایل

استادیار

• Survival behaviors
• Neural circuits
• Instinctual behaviors
• +۴ مورد دیگر

Stefanos Stagkourakis is an Assistant Professor in Molecular Life Science at Karolinska Institutet and a SciLifeLab Fellow 2024. He leads the Stagkourakis Lab, which sits at the intersection of Karolinska Institutet’s Department of Neuroscience and SciLifeLab. His research focuses on neural and neurohormonal mechanisms governing evolutionarily conserved survival behaviors like aggression, fear, parental care, and metabolic responses. Academic Rank: Assistant Professor Institution: Karolinska Institutet Collaboration: SciLifeLab (Sweden’s national hub for data-driven life science) His work employs advanced in vivo techniques including large-scale electrophysiology, multi-color biosensor imaging with miniscopes, and two-photon microscopy to study brain-wide computations in freely moving mice. Key interests include stimulus-specific hypothalamic encoding, experience-dependent plasticity, and hormonal state influences on circuit dynamics, particularly testosterone and oxytocin. The lab’s publication trends include mapping neural nodes critical to instincts, analyzing mesoscale hypothalamic representations, and investigating dysregulated circuits in neuropsychiatric contexts like anxiety disorders and metabolic dysfunctions. Recent work explores dopamine systems, electrical coupling rules, and cerebellar motor learning mechanisms. Scientific recognition includes the SciLifeLab Fellowship , supporting his lab’s mission to bridge molecular, cellular, and systems neuroscience. The team integrates computational and experimental expertise, with ongoing recruitment for researchers in neuroscience, engineering, and computational biology.

Sathish Venkatachalemمشاهده پروفایل

استاد

• Pulmonary Medicine
• Critical Care Medicine
• Sleep Medicine
• +۷ مورد دیگر

Sathish Venkatachalem, PhD is a Professor of Medicine and Laureate Chair in Molecular Medicine at the University of Oklahoma Health Sciences Center, with additional appointments as Adjunct Professor of Pharmaceutical Sciences and Pathology. He serves as Co-Director of Research for the Section of Pulmonary, Critical Care and Sleep Medicine within the Department of Medicine. Previously, he held faculty positions at North Dakota State University (2016-2025) and Mayo Clinic (2012-2016). Dr. Venkatachalem's research program focuses on sex differences in lung diseases, particularly examining how estrogens impact asthmatic airways and why women are disproportionately affected by conditions like lymphangioleiomyomatosis (LAM). His laboratory investigates the molecular mechanisms underlying asthma, COPD, and pulmonary hypertension, with emphasis on sex steroid signaling pathways and their implications for disease pathogenesis and treatment. His work bridges basic science with translational applications, including nanomedicine-based drug delivery systems. His recent publications reveal a strong focus on kisspeptin signaling in airway function, nicotine effects on airway cells, and sex hormone influences on respiratory diseases. The research demonstrates interdisciplinary approaches combining molecular biology, cell physiology, and translational medicine to address sex-specific differences in lung pathology. His scientific achievements include: Laureate Chair in Molecular Medicine (2025) APS Select Awards (2020, 2021) Innovation in Teaching Award from NDSU (2024) Rising Star of Research Award from American Thoracic Society (2016) Multiple Young Clinical Scientist Awards from Flight Attendants Medical Research Institute Dr. Venkatachalem mentors a diverse research team including postdoctoral fellows, research scholars, and graduate students. His laboratory is supported by multiple NIH grants (NHLBI, NIA, NIGMS R01/RF1), reflecting the significance and impact of his work in pulmonary medicine. He serves on editorial boards for Frontiers in Physiology and Frontiers in Allergy, contributing to scientific discourse in his field.

Adam Moeserمشاهده پروفایل

استاد

• Gastrointestinal neuro-immune disorders
• Early-life adversity and developmental programming
• Mast-cell biology
• +۳ مورد دیگر

Adam Moeser, DVM, MS, PhD, is Professor and Matilda R. Wilson Endowed Chair in Large Animal Clinical Sciences at Michigan State University’s College of Veterinary Medicine. He also serves as Associate Professor in the Neuroscience Program and directs the Gastrointestinal Stress Biology Laboratory (GISBL), a multidisciplinary team investigating how early-life adversity and biological sex interact to shape lifelong gut-brain axis disorders. Education: BS, University of Massachusetts Amherst (2000) MS, Animal Nutrition, North Carolina State University (2001) PhD, Physiology, North Carolina State University (2006) DVM, North Carolina State University (2008) NIH T32 Post-doctoral Fellowship, University of North Carolina at Chapel Hill NIH K08 Award, Duke University (2008) Research Focus: Dr. Moeser’s NIH-, USDA- and industry-funded program integrates rodent, pig and translational models to dissect the neuro-immune mechanisms by which early-life stress programs mast-cell hyper-responsiveness, intestinal barrier dysfunction, visceral pain and comorbid neurobehavioral disorders such as depression and anxiety. Central themes include: Mast-cell biology and sex-specific immune programming Brain–gut axis signaling via corticotropin-releasing factor (CRF) receptors Epigenetic and transcriptomic reprogramming of innate immune cells Translational applications to human IBS, IBD and food allergy Scientific Awards & Honors: Matilda R. Wilson Endowed Chair in Large Animal Clinical Sciences NIH K08 Career Development Award (NIDDK) NIH T32 Post-doctoral Fellowship (Center for Gastrointestinal Biology and Disease) Advising & Grants: Dr. Moeser has mentored >20 graduate students and post-docs who have received NIH F30, K01 and NARSAD awards and now hold faculty, industry and clinical positions. His laboratory has been continuously funded since 2008 by multiple NIH R01/R21 grants, USDA-NIFA, and private-industry sponsors. Laboratory & Team: The Gastrointestinal Stress Biology Laboratory (GISBL) is located in the MSU College of Veterinary Medicine. Current team members include research associate Dr. Yu Ping Tang and PhD student Janelle Victoria LeMon, together with numerous alumni now in academia, industry and clinical residency programs.

Vinay Parikhمشاهده پروفایل

دانشیار

• Behavioral/Cognitive Neuroscience
• Psychopharmacology
• Neuromodulatory Systems
• +۵ مورد دیگر

Vinay Parikh is an Associate Professor in the Department of Psychology at Temple University's College of Liberal Arts and serves as Director of the Neuroscience Program. He also holds an affiliated faculty position at the Center for Substance Abuse Research, Lewis Katz School of Medicine. PhD in Life Sciences/Pharmacology from Punjabi University Postdoctoral training at Medical College of Georgia, Ohio State University, and University of Michigan Dr. Parikh's research focuses on neuromodulation of cognition in health and disease, particularly examining forebrain cholinergic and glutamatergic pathways in attention and executive functions. His work explores neurotrophins in circuit adaptations related to aging, Alzheimer's disease, schizophrenia, and nicotine addiction, integrating environmental factors with synaptic mechanisms. Key article themes include: Neurodegeneration in Alzheimer's models Stress-cholinergic interactions Neurotransmitter clearance mechanisms Developmental nicotine exposure effects Neurotrophic factor roles Chemogenetic circuit analysis His lab (NECO Lab) investigates brain network dynamics and cognitive trajectories during aging and developmental transitions, employing preclinical and human models to develop therapeutic strategies.

Anthony Downsمشاهده پروفایل

پژوهشگر

• Neuroscience
• Neuropharmacology
• Substance Use Disorders
• +۴ مورد دیگر

Anthony Downs is a Researcher in the Department of Pharmacology at the UNC School of Medicine. His work focuses on neurobiological mechanisms underlying substance use disorders and neurodegenerative diseases, particularly examining the locus coeruleus and basolateral amygdala. He is affiliated with the McElligott Lab. Neurobiology of Opioid Use Disorder Locus Coeruleus Plasticity Dopamine Signaling in Dystonia Neuroimmune Pathways Dr. Downs investigates how neuroplasticity in noradrenergic and dopaminergic systems contributes to addiction and neurodegenerative disease progression. His recent publications highlight interactions between tauopathy and alcohol consumption, opioid withdrawal effects on affective states, and cholinergic-dopaminergic receptor dynamics in dystonia models. Research employs in vivo models, electrophysiology, and molecular profiling. Key publication trends span Neuroscience, Neuropharmacology, and Neurogenetics, with subfields covering opioid relapse mechanisms, locus coeruleus excitability, striatal signaling pathways, and neuroimmune interactions. Notable journals include Neurobiology of Disease , Addictive Neuroscience , and Neuroscience .

Razvan Stefan Boiangiuمشاهده پروفایل

استادیار

• Experimental Neuroscience
• Neurodegenerative Diseases
• Nicotine Derivatives
• +۷ مورد دیگر

Razvan Stefan Boiangiu is an Assistant Professor at the Faculty of Biology , Alexandru Ioan Cuza University of Iasi (UAIC). His research focuses on experimental neuroscience, particularly investigating natural and semi-synthetic compounds in neurodegenerative contexts, including nicotine derivatives and plant-based bioactives. He employs zebrafish ( Danio rerio ), rodents, and transgenic models (e.g., 5xFAD mice) to study cognitive deficits and neuroprotective mechanisms. Education: PhD in Biology (Neurobiology Specialization), UAIC (2021, Summa Cum Laude) MSc in Microbial and Cellular Biotechnology, UAIC (2017) BSc in Biochemistry, UAIC (2015) Research Interests: Neurodegenerative disease models (Alzheimer’s) Nicotine metabolites and bacterial genomics ( Paenarthrobacter nicotinovorans ) Antioxidant and cholinomimetic plant extracts 3D molecular models in education Key Projects: Project Director: Development of 6-hydroxy-L-nicotine extraction methods (GI-UAIC-2022-08, €10,000) Genome sequencing of Paenarthrobacter nicotinovorans Awards: FEBS-IUBMB-ENABLE Travel Grant (2023) Best Poster at ICNPU 2023 2 Excellence Awards from UAIC Teaching & Outreach: Developed 3D molecular models for educational use Active in scientific conferences and public engagement

Sean Wardمشاهده پروفایل

استاد

• Gastrointestinal Physiology
• Cellular Electrophysiology
• Smooth Muscle Biology
• +۳ مورد دیگر

Sean Ward is a Professor in the Department of Physiology and Cell Biology at the University of Nevada School of Medicine. His research focuses on the functional roles of interstitial cells of Cajal (ICCs) in gastrointestinal (GI) tract physiology, particularly their roles in pacemaker activity, slow wave generation, and neuromuscular transmission. His lab employs multi-faceted approaches including electrophysiology, molecular biology, and calcium imaging to study ICCs' contributions to GI motility and their disruption in disease states. Research interests include ICC-mediated pacemaker activity in visceral organs, stretch receptor functions, and neural signaling pathways in the gut. Recent work highlights ICCs' critical roles in propagating slow waves, mediating cholinergic/nitrergic inputs, and maintaining gastric muscle responses. Publications span gastrointestinal physiology, cardiovascular biology, and astrophysics collaborations, reflecting interdisciplinary approaches to understanding cellular mechanisms in health and disease. Key collaborations within the School of Medicine and with other departments have enabled advancements in ICC function and their implications for conditions like diabetes-related GI motility disorders. Ongoing studies explore ICC dysfunction in obesity and diabetes, as well as novel therapeutic targets for motility disorders.

Niels Christian Danboltمشاهده پروفایل

استاد

• Neurochemistry
• Neuroscience
• Glutamate Transporters
• +۵ مورد دیگر

Niels Christian Danbolt is a Professor at the University of Oslo's Faculty of Medicine, affiliated with the Neurotransporter Laboratory. His research focuses on neurotransmitter transport mechanisms, particularly glutamate transporters in neurological disorders like epilepsy and neurodegeneration. He holds a PhD and MD from the University of Oslo (1993 and 1987, respectively). Education: PhD, Faculty of Medicine, University of Oslo (1993) Medical Doctor (MD), Faculty of Medicine, University of Oslo (1987) Research Interests: His work explores glutamate transporter function in health and disease, including their roles in epilepsy, neurodegeneration, and metabolic processes. Danbolt's lab investigates the molecular mechanisms underlying neurotransporter regulation and their implications for neurological conditions. Publications Trends: Recent articles highlight studies on glutamate transporters' roles in aging, inflammation, and seizure propagation, using mouse models to dissect genetic and cellular mechanisms. Key themes include astrocyte dysfunction, neuroinflammation modulation, and protein localization techniques. Awards: Member of the Norwegian Academy of Science and Letters (2004) Top Scientist Program (Toppforskningsprogrammet) recognition (2001) Multiple teaching awards for excellence in preclinical education Lab and Teams: The Neurotransporter Laboratory focuses on translational research into neurotransmitter transport systems. Collaborations involve interdisciplinary projects exploring genetic deletions, protein reconstitution, and in vivo models of neurological disease.

Waschkeمشاهده پروفایل

استاد

• Cell Adhesion
• Desmosome Biology
• Autoimmune Diseases
• +۶ مورد دیگر

Prof. Waschke leads the research group at the Institute of Anatomy, Ludwig-Maximilians-Universität München, focusing on desmosome biology and its role in diseases such as pemphigus, arrhythmogenic cardiomyopathy (AC), and inflammatory bowel disease (IBD). His work explores desmosome dysfunction mechanisms and potential therapeutic strategies. Key projects include signaling pathways regulating cardiomyocyte cohesion, epidermal barrier integrity, and endothelial barrier function during inflammation. Research interests span desmosomal cadherins (Dsg2, Dsg3), EGFR signaling, and cAMP-mediated pathways. Collaborations include work with the University of Würzburg on Crohn's disease mechanisms. Recent findings highlight catalytic antibodies' role in AC and Dsg2-based therapies. Prof. Waschke's team uses advanced techniques like atomic force microscopy and iPSC-derived models for translational studies. Students and collaborators are engaged in projects ranging from pemphigus autoantibody mechanisms to endothelial barrier stabilization. Publications emphasize desmosome dysfunction in cardiovascular and epithelial disorders, with a focus on molecular and pharmacological interventions. Future work aims to translate findings into clinical treatments for desmosome-related diseases.

• Neuroscience
• Neuroimaging
• Neurology
• +۳ مورد دیگر

Zhuo Wang is a Research Assistant Professor (Part-Time) in the Department of Psychiatry and the Behavioral Sciences at the University of Southern California. His research focuses on neurobiological mechanisms underlying pain, stress, and cognitive dysfunction, with a particular emphasis on neuroimaging techniques and animal models. Key areas of investigation include visceral pain pathways, stress-induced neural reorganization, and the impact of exercise on brain connectivity and behavior. Wang employs multidisciplinary approaches integrating pharmacological interventions, functional brain mapping, and behavioral assays in rodent models to explore these topics. His work frequently addresses sex differences in neural responses, synaptic plasticity, and the gut-brain axis. Recent studies highlight exercise’s role in ameliorating neurological deficits and improving cognitive flexibility in Parkinsonian models, as well as the interplay between cerebral circuits and bladder dysfunction in chronic pelvic pain syndromes. Awards and grants: None explicitly listed in the provided text. Advising and collaborations: No students or grants are detailed here, but his publications suggest active collaboration with neuroscientists, clinicians, and bioengineers in translational research.

• Neuroscience
• Proteomics
• Neurodegenerative Diseases
• +۳ مورد دیگر

Dr. Ka Wan Li is a Visiting Fellow at the Vrije Universiteit Amsterdam's Faculty of Science, affiliated with the Molecular and Cellular Neurobiology department and multiple neuroscience institutes including Amsterdam Neuroscience. His research focuses on neurodegenerative diseases, proteomics, and molecular mechanisms of synaptic function. He has contributed to over 145 peer-reviewed publications, including studies on Alzheimer’s disease, GABA receptor proteomics, and biomarker discovery. Research Interests: His work integrates proteomics techniques to study neurodegenerative pathways, synaptic plasticity, and biomarker identification in conditions like Alzheimer’s and frontotemporal dementia. Recent studies explore nerve growth factor mimetics, GABA receptor subunit variations, and CSF biomarkers for tau pathology. Articles Trends: Recent publications emphasize mouse models for disease mechanisms, neuroprotective agents, and advanced proteomic methods like Blue Native PAGE. Collaborations span institutions globally, reflecting interdisciplinary approaches to neurobiology challenges. Advising & Grants: Supervised 7 PhD theses but no specific grant details provided. His work aligns with UN Sustainable Development Goals related to health and innovation. Labs/Teams: Active in Amsterdam Neuroscience’s Cellular & Molecular Mechanisms and Neurodegeneration divisions, leveraging collaborative networks for translational research.

Mark S Moehleمشاهده پروفایل

استادیار

• Neurological Disorders
• Movement Disorders
• Parkinson’s Disease
• +۵ مورد دیگر

Mark S Moehle is an Assistant Professor in the Department of Pharmacology and Therapeutics at the University of Florida. His research focuses on understanding cellular and molecular mechanisms underlying neurological disorders such as Parkinson’s disease, dystonia, and Lewy Body Dementia. He leads the Moehle Laboratory, which employs pharmacological, electrophysiological, and behavioral techniques to investigate therapeutic strategies targeting muscarinic acetylcholine receptors (M4) and LRRK2 pathways. Moehle holds a PhD from Vanderbilt University and completed postdoctoral training at the University of Florida. He teaches courses including Pharmacotherapeutics I, Principles of Pharmacology, and Neuroscience seminars. Active grants include studies on α-synuclein pathology, cholinergic mechanisms in Lewy Body Dementia, and M4 receptor modulation in Parkinson’s disease. His work bridges basic science and translational research, aiming to develop novel treatments for movement disorders. Education: PhD in Pharmacology (2015), Vanderbilt University Postdoctoral Fellowship (2015–2020), University of Florida Bachelor of Science (2010), Centenary College of Louisiana Research Interests: Molecular mechanisms of α-synuclein aggregation and neurodegeneration Role of M4 muscarinic receptors in movement disorder pathogenesis Genetic and pharmacological modulation of LRRK2 signaling Development of antiparkinsonian and antidystonic therapies Grants & Funding: Principal Investigator: NIH NINDS (Lewy Body Dementia research) Michael J. Fox Foundation (M5 modulators and α-synuclein studies) Co-Investigator: DYT1 dystonia modeling Labs & Teams: Moehle Lab: Focused on circuit-level and biochemical analysis of movement disorder models Collaborations with neurology and pharmacology departments at UF

Margaret E. Riceمشاهده پروفایل

استاد

• Neurochemistry
• Neurophysiology
• Nigrostriatal dopamine pathway
• +۵ مورد دیگر

Margaret E. Rice, PhD is a Professor in both the Department of Neurosurgery and Department of Neuroscience at NYU Grossman School of Medicine. She also serves as Vice Chair of Research in the Department of Neurosurgery. Dr. Rice is an investigator in the Neuroscience Institute and a member of the Marlene and Paolo Fresco Institute for Parkinson's and Movement Disorders at NYU Langone. Her laboratory studies the neurochemistry and neurophysiology of the nigrostriatal dopamine pathway with NIH funding. Dr. Rice's research focuses on factors that regulate dopamine release, which is critical for motor and reward pathways in the brain. Current projects include examining how diet and metabolic hormones (insulin and leptin) modulate dopamine release in the striatum, investigating the influence of exercise on dopamine levels, and studying how Parkinson's-related proteins like alpha-synuclein affect dopamine neuron physiology. Her laboratory employs advanced techniques including fast-scan cyclic voltammetry, optogenetics, patch-clamp recording of basal ganglia neurons, and immunohistochemistry, primarily using ex vivo rodent brain slices. Analysis of Dr. Rice's recent publications (2016-2025) reveals a consistent focus on dopamine regulation mechanisms, particularly the interplay between metabolic factors and neurotransmission. Her work spans from molecular mechanisms of somatodendritic dopamine release to behavioral implications for understanding motivation and movement disorders. The publications demonstrate an evolution from basic dopamine release mechanisms to increasingly sophisticated investigations of metabolic-neural interactions with direct relevance to Parkinson's disease. Her 2015 Nature Communications paper demonstrated that insulin enhances striatal dopamine release by activating cholinergic interneurons, revealing insulin's role as a reward signal Her ongoing work on leptin shows it promotes dopamine release in both nigrostriatal and mesolimbic pathways through distinct mechanisms Recent studies examine how exercise increases striatal dopamine release through BDNF-dependent mechanisms Dr. Rice serves on the Scientific Advisory Board of the Parkinson's Foundation, demonstrating her standing in the field. Her research has significant implications for understanding the neural basis of motivation, reward pathways, and Parkinson's disease pathology. Dr. Rice has mentored numerous researchers including Jyoti C. Patel (Research Associate Professor), Maria Mancini (Fresco Fellow), Takuya Hikima (Instructor), and Letizia Zanetti (Visiting Fresco Scholar). Her laboratory maintains an active research program with multiple ongoing projects examining the intersection of metabolic regulation and dopamine neurotransmission, with potential applications for understanding obesity, diabetes, and neurological disorders.