معرفی
Nichola Lax is a Research Fellow at Newcastle University specializing in the neuropathological mechanisms of mitochondrial disorders. Her work focuses on neurological manifestations including Alpers' syndrome, epilepsy, and Lewy body dementia, with extensive collaboration with leading mitochondrial researchers such as Emeritus Professor Doug Turnbull and Professor Robert Taylor.
Her research interests include:
- Mitochondrial Diseases
- Neurodegenerative Disorders
- Neuropathology
- Epilepsy mechanisms
- Lewy Body Dementia pathology
- Mitochondrial DNA mutation effects
Analysis of her 2016-2023 publications reveals consistent investigation of mitochondrial dysfunction in neurodegeneration, particularly emphasizing astrocytic pathology, respiratory chain defects in specific neuronal populations (inhibitory interneurons, Purkinje cells), and seizure generation mechanisms. Her work employs advanced techniques including multiplex immunofluorescence, CLARITY tissue clearing, and in vitro seizure modeling to establish pathological correlations between mitochondrial defects and clinical phenotypes.
No information was found regarding scientific awards, student advising, research grants, or laboratory infrastructure in the provided text.