جست‌وجوی استاد و پژوهشگر

• Cancer and Oncology
• Cell and Molecular Biology
• Developmental Biology

Johan Holmberg is affiliated to research at the Department of Cell and Molecular Biology, Karolinska Institutet. His academic rank is Researcher, and his work spans Cancer and Oncology, Cell and Molecular Biology, and Developmental Biology. Doctor of Philosophy, Karolinska Institutet, 2003 Docent, Karolinska Institutet, 2018 His research focuses on neuroblastoma pathogenesis, hypoxia signaling in cancer, epigenetic regulation of neuronal identity, and mechanisms of neural progenitor differentiation. Key contributions include identifying oncogenic drivers in neuroblastoma, elucidating roles of HIF proteins in tumor suppression, and exploring chromatin dynamics in dopaminergic neurons. Recent publications highlight studies on aberrant RNA splicing in neuroblastoma, PRC2-mediated neuronal stability, and oxygen-sensitive mitochondrial regulation in Von Hippel-Lindau syndrome. Collaborative work spans tumor immunology, glioblastoma mechanisms, and developmental gene networks. Current affiliations include Karolinska Institutet's Department of Cell and Molecular Biology, with no listed scientific awards or student advisories.

• Cellular Senescence
• Autophagy
• Aging
• +۱۲ مورد دیگر

Federico Pietrocola is a Principal Researcher at the Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm. He leads the Cellular Stress in Health and Disease research group, focusing on molecular mechanisms linking cellular senescence, autophagy, and aging pathologies. His work bridges basic science with translational applications in cancer, metabolic disorders, and fibrotic diseases. His research investigates cellular senescence as a driver of age-related pathologies and autophagy as a protective mechanism. Key areas include: Senescence-induced fibrosis in lung and kidney diseases Immunogenic properties of senescent cells in cancer immunity Polyamine metabolism (e.g., spermidine) in longevity Metabolomic regulation of stress responses Senolytic drug development targeting ACBP/DBI and COPI pathways Analysis of recent publications (2023-2025) reveals a dominant focus on senescence-immune interactions and metabolism-targeted therapies . His group pioneered senolytic screening methods and demonstrated how senescent cells trigger lung fibrosis in humanized models. Strong emphasis on translating findings into treatments for fatty liver disease, chronic kidney disease, and cancer via autophagy modulation. Scientific Awards: No awards listed in provided profile information Dr. Pietrocola currently directs a major Swedish Research Council grant (2024-2027) for senescence-targeted cancer immunotherapy. He secured consecutive Novo Nordisk Foundation grants (2021-2023) targeting polyamine metabolism in senescence-related disorders. His earlier project (2020-2023) explored immune checkpoint therapies against aging pathologies. While specific students aren't named, his publications indicate active mentorship through collaborative projects. His Cellular Stress in Health and Disease group develops innovative models including humanized pulmonary fibrosis systems and metabolomic platforms for single-cell analysis. Current work emphasizes senescence-specific immune checkpoints, microvascular aging in kidney disease, and polyamine-based interventions to counteract tissue degeneration across multiple disease contexts.

• Stem Cell Research
• Hematopoiesis
• Molecular Biology
• +۳ مورد دیگر

Roger Rönn is a Researcher at Lund University’s Faculty of Medicine, affiliated with the Division of Molecular Medicine and Gene Therapy and the national initiative StemTherapy . His work focuses on stem cell biology and regenerative medicine, particularly in hematopoietic development from pluripotent stem cells. Key Research Themes : Hematopoietic stem cells, retinoic acid signaling, CD90+ progenitors, cyclic AMP modulation, endothelial-to-hematopoietic transition, and stromal cell applications. Published works (2015–2023) demonstrate expertise in stem cell differentiation protocols, oxidative stress mitigation, and retinoid pathway regulation. Articles frequently address challenges in generating functional hematopoietic cells for therapeutic use, with methods involving Epac axis activation and hemogenic endothelium manipulation. Citations and patent references reflect translational impact. His research intersects with UN Sustainable Development Goals (SDG3: Good Health and Well-being; SDG9: Industry Innovation) through advancements in cell therapy and regenerative medicine. Collaborations with Woods, Parmar, and Sitnicka are evident, with works widely disseminated via social media ( 340+ X posts ) and 22 patents citing his research.

• Lipidomics
• Metabolomics
• Analytical Chemistry
• +۳ مورد دیگر

David Balgoma is a Researcher at Uppsala University's Department of Medicinal Chemistry; Analytical Pharmaceutical Chemistry, specializing in lipidomics and metabolomics with advanced analytical chemistry methodology development. His work integrates mass spectrometry, chromatography, and computational approaches to address biomedical challenges. His research focuses on: Lipid metabolism alterations in liver cancer and response to chemotherapeutics (e.g., doxorubicin) Development of novel analytical techniques for lipid separation and characterization Role of lipids in viral infections and deep-sea organism physiology Engineering ROS-sensitive biomaterials for wound healing applications Analysis of his 2022-2024 publications reveals consistent innovation in analytical methodology (chromatographic optimization, peak characterization algorithms) coupled with biological insights into lipid pathways in disease. His interdisciplinary approach bridges analytical chemistry, oncology, and biomaterials science, frequently appearing in high-impact journals like Analytica Chimica Acta and Molecular Metabolism.

Nicholas Leighمشاهده پروفایل

مدرس ارشد

• Limb Regeneration
• Cancer Resistance Mechanisms
• Regenerative Immunology
• +۷ مورد دیگر

Nicholas Leigh serves as a Senior Lecturer at Lund University's Faculty of Medicine, holding multiple prestigious research positions including Principal Investigator at StemTherapy: National Initiative on Stem Cells for Regenerative Therapy and LUCC: Lund University Cancer Centre. He also manages the Regenerative Immunology research team and is affiliated with the Lund University Bioimaging Center. Dr. Leigh's research focuses on the intersection of regeneration biology and cancer resistance, particularly examining how salamanders and newts can regenerate limbs while maintaining cancer resistance. His work explores cellular senescence, immune responses during regeneration, and the molecular mechanisms underlying tissue regrowth. He investigates how non-coding RNA landscapes and repeat elements contribute to regenerative capabilities in amphibians, with potential applications for human regenerative medicine. His recent publications demonstrate a strong trend toward understanding the genomic and molecular basis of regeneration, with particular emphasis on newt and salamander models. The research spans from fundamental genomic analysis to practical applications in cancer resistance and tissue engineering, showing increasing interdisciplinary collaboration between biology, imaging technology, and computational analysis. Docent in Molecular Medicine (2023) Roswell Park Outstanding Ph.D. Dissertation Award (2016) Dr. Leigh currently leads three active research projects totaling over three years of funded research, including 'Deciphering the balance between regeneration and tumorigenesis' funded by Cancerfonden (2024-2026), 'Identifying the origins of cancer resistance in salamanders' (2023-2026), and 'Regeneration as a cancer resistance mechanism' funded by the Crafoord Foundation (2023-2025). His work contributes to multiple UN Sustainable Development Goals related to good health and well-being. His research team operates at the intersection of molecular medicine, gene therapy, and regenerative biology, utilizing advanced imaging techniques and genomic analysis to study regeneration in non-traditional model organisms. The lab maintains strong collaborations with international researchers studying amphibian biology and cancer resistance mechanisms.

Carina Bernardoمشاهده پروفایل

پژوهشگر

• Bladder Cancer
• Genomics
• Molecular Pathology
• +۵ مورد دیگر

Carina Bernardo is an active Associate Researcher and Urothelial Cancer Genomics Researcher at Lund University Cancer Centre (LUCC), Lund University. Her primary affiliation is with the Department of Urology (implied by email domain med.lu.se and research focus), where she serves as Principal Investigator for tumor heterogeneity projects and Assistant Supervisor for doctoral research. Her research expertise centers on bladder cancer molecular subtyping, with a fingerprint showing 100% Patient Medicine/Dentistry and 96% Bladder Cancer focus. Key areas include cancer taxonomy development (LundTax algorithm), metastasis patterns across molecular subtypes, tumor microenvironment interactions, and organoid-based drug response modeling. Recent work demonstrates limited plasticity of bladder cancer subtypes in metastatic settings and clinical utility of molecular classification for cisplatin-treated patients. Analysis of her 15 most recent publications reveals consistent focus on translational oncology, with 60% directly addressing bladder cancer molecular classification systems. Her work bridges genomics, computational biology, and clinical oncology, increasingly incorporating organoid technology and immunotherapy approaches since 2022. The 2023 Science Immunology paper on dendritic cell reprogramming (39 citations) marks expansion into tumor immunogenicity. Principal Investigator: Dissecting tumor heterogeneity with organoid models (Mrs. Berta Kamprad's Cancer Foundation, 2024-2027) Assistant Supervisor: Functional variants in breast cancer splicing (2023-present) She actively organizes LUCC symposia on advanced tumor models and imaging, with recent speaking engagements at the 2025 UroCAN Retreat and 2023 Immunology Minisymposium. Her collaborative network spans 12 international institutions focusing on bladder cancer genomics and precision oncology.

• Neuroscience
• Cellular Reprogramming
• Neurodegenerative Diseases
• +۵ مورد دیگر

Daniella Ottosson is a Senior Lecturer, Docent, and Wallenberg Academy Fellow at Lund University, affiliated with the Division of Molecular Medicine and Gene Therapy. She leads the Regenerative Neurophysiology research team and contributes to multidisciplinary initiatives like MultiPark (Parkinson's disease research) and StemTherapy (national stem cell network). Her research focuses on direct reprogramming to generate subtype-specific neurons (particularly interneurons ) from glia or stem cells, using animal models , human stem cell cultures , electrophysiology , and RNA sequencing . This work aims to address neurodegenerative diseases and psychiatric disorders through cell therapy and neuronal network repair . Key article trends include 3D cell culture systems for neuronal generation, photothermal imaging of living tissues, and CRISPR-based disease models . She has published extensively on interneuron dysfunction , synaptic plasticity , and novel reprogramming techniques . Scientific Awards : Wallenberg Academy Fellow (2021) Per-Eric and Ulla Schyberg Stiftelse (2020) Harald and Greata Jeansson Award (2019) Lecturer Invitation (2012) Plenary Lecturer (2012) She supervises PhD students, organizes conferences like Neuroscience Day , and collaborates internationally on projects related to Alzheimer's disease and neuronal activity in amyloid aggregation . Her lab explores self-healing brain mechanisms and in vivo reprogramming for neurological disorders.

Shayini Kidnapillaiمشاهده پروفایل

پژوهشگر ارشد

• Neuroscience
• Regenerative Neurophysiology
• Stem Cell Research
• +۳ مورد دیگر

Shayini Kidnapillai is a Research Fellow at Lund University's Faculty of Medicine, affiliated with initiatives like Regenerative Neurophysiology, MultiPark (Parkinson's disease research), and StemTherapy (stem cell therapy). Her work focuses on cellular reprogramming and neuroscience. Primary Role: Research Fellow Institution: Lund University Key Affiliations: MultiPark, StemTherapy, Advanced Cancer Her research spans Neuroscience , Stem Cell Reprogramming , and Molecular Neurobiology . Recent studies include direct conversion of fibroblasts to GABAergic interneurons and functional analysis of reprogrammed neurons. Key trends in her publications involve neuronal maturation , microRNA regulation , in vitro/in vivo modeling , and neurodegenerative disease therapy . She has organized major events like Neuroscience Day 2025 and UniStem Day 2024 , contributing to stem cell outreach and Parkinson's disease research.

• Neuroscience
• Stem Cell Research
• Neurodegenerative Diseases
• +۳ مورد دیگر

Francesco Trovato is a Research Fellow at Lund University, affiliated with the StemTherapy national initiative on stem cells for regenerative therapy and the multidisciplinary MultiPark research program focused on Parkinson's disease. His work bridges neuroscience , stem cell biology , and cellular reprogramming . Research Themes : Glioblastoma, astrocyte differentiation, transcription factor-driven cell conversion. Activities : Organizer and speaker at seminars including LUCC-CNS events on glioblastoma reprogramming and human organoid models. His recent publications highlight the therapeutic potential of astrocytic differentiation in cancer models and methods for converting fibroblasts into functional astrocytes.

Andreas Bruzeliusمشاهده پروفایل

پژوهشگر ارشد

• Neuroscience
• Stem Cell Research
• Neurodegenerative Diseases
• +۳ مورد دیگر

Dr. Andreas Bruzelius is a Research Fellow and Postdoctoral Fellow at Lund University's Faculty of Medicine, affiliated with the Developmental and Regenerative Neurobiology group, StemTherapy national stem cell initiative, and MultiPark multidisciplinary Parkinson's research consortium. His work focuses on neurodegenerative diseases and regenerative therapies. Primary Affiliation: Lund University Faculty of Medicine Consortium Memberships: StemTherapy, MultiPark Research Interests: Specializing in dopaminergic neuron regeneration, glial cell reprogramming, and neurodegenerative disease modeling using stem cell technologies. Key areas include Parkinson's disease, frontotemporal dementia, and human brain organoid development. Publication Trends: Recent work demonstrates expertise in single-cell transcriptomics, CRISPR-engineered disease models, and scaffold-driven organoid self-assembly. Collaborative articles appear in journals like PNAS, Cell Reports Methods, and Brain Communications. Academic Activities: Active contributor to neuroscience workshops and conferences including UniStem Day (2024), Neuroscience Day (2023), and Unistem Day (2020). Presents at international events focused on stem cell science and neuroregeneration. Laboratory Affiliation: Works within the MultiPark consortium's collaborative framework for Parkinson's research, utilizing Lund University's Regenerative Neurobiology core facilities.

Malin Parmarمشاهده پروفایل

استاد

• Stem Cell Biology
• Neurosciences
• Cell Differentiation
• +۷ مورد دیگر

Malin Parmar is a Professor at Lund University 's Faculty of Medicine , leading the Department of Experimental Medical Science 's Developmental and Regenerative Neurobiology group. She serves as Principal Investigator for StemTherapy (National Stem Cell Initiative) and MultiPark (Multidisciplinary Parkinson's Research). Her work spans translational stem cell biology , neuronal differentiation , and brain repair strategies . Research Focus: Stem cell fate specification in brain development Subtype-specific neuron generation from human stem cells In vitro glia-to-neuron conversion technologies In vivo endogenous glia reprogramming Parkinson's disease-focused regenerative therapies Key Research Trends: Recent publications highlight organoid modeling , single-cell transcriptomics , and lineage tracing in Parkinson's research. Work emphasizes precision neurotechnology and clinical translation of autologous cell therapies. Scientific Recognition: 2024 - Oon Award for Preventative Medicine 2018 - Bengt Falcks Prize in Neuroscience 2016 - Eric K. Fernström Prize 2015 - Article of the Month 2015 - Finalist, Stem Cell Investigator Award Academic Leadership: Active in conference organization (Neuroscience Day 2024/2025 program committees) and media engagements (TV, podcasts). Supervises multiple PhD students while managing international collaborations.

• Cancer and Oncology
• Genetics and Genomics
• Physiology and Anatomy
• +۳ مورد دیگر

Randall S. Johnson is a Professor in the Department of Cell and Molecular Biology at Karolinska Institutet. His research focuses on hypoxia-induced responses, particularly the roles of Hypoxia-Inducible Factors (HIF) in physiological and pathological contexts. His lab uses genetic models to study how HIF isoforms regulate cellular responses to low oxygen levels in cancer, immune function, and metabolic processes. Research Interests: Effects of hypoxia on tumor growth and metastasis Regulation of T cell immunity under hypoxic conditions Metabolic pathways influenced by HIF in cancer and inflammation Grants & Awards: Swedish Research Council (2023–2026) Wallenberg Scholar (2019) 2016 Albert Lasker Basic Medical Research Award Key Collaborations: The Johnson Group collaborates with institutions globally to advance understanding of HIF’s role in immunity and cancer. His team includes researchers like Madara Brice (PhD student) and postdocs such as Brennan Wadsworth.

• Cancer and Oncology
• Cell and Molecular Biology
• Neurosciences
• +۳ مورد دیگر

Bertrand Joseph is a Professor at the Department of Toxicology within the Institute of Environmental Medicine at Karolinska Institutet. His research focuses on molecular mechanisms of cell death, particularly in neurodegenerative diseases and cancer, emphasizing the role of microglia in inflammatory responses and disease progression. He holds a Docent degree from Karolinska Institutet (2004). Research interests include microglial diversity, caspase signaling, and epigenetic regulation in neuroinflammation. His work integrates molecular biology, cell biology, and neurobiology to explore how cellular decision-making processes (life vs. death) impact diseases like Alzheimer’s, Parkinson’s, and glioma. Recent publications highlight his team’s discoveries on microglial subtypes, ARG1-expressing microglia’s role in brain development, and mechanisms linking microglial dysfunction to autism and cancer. Key findings include the identification of novel pathways regulating neuroinflammation and tumor-supportive microglia phenotypes. No scientific awards or grants are explicitly listed in the provided texts. His lab, 'Toxicology – Bertrand Joseph’s Research Group,' investigates diverse aspects of microglial biology, including their response to environmental toxins and neurodegenerative triggers.

• Cell and Molecular Biology
• Medical Genetics and Genomics
• Microbiology in the Medical Area
• +۳ مورد دیگر

Anna Karlsson is a Professor and Specialist Physician at the Department of Laboratory Medicine, Karolinska Institutet. She leads the Anna Karlsson Research Group, focusing on nucleoside analogues, mitochondrial DNA synthesis, and their applications in treating viral diseases and cancer. Her work explores drug activation mechanisms and side effects linked to mitochondrial dysfunction. Education: Docent (1996) at Karolinska Institutet. Research Interests: Investigates nucleoside analogues' pharmacology, including their activation pathways and impacts on mitochondrial function. Key areas include HIV therapy optimization, cancer metabolism, and genetic disorders caused by mitochondrial DNA defects. Techniques used include cell and molecular biology, transgenic models, and enzyme assays. Publications highlight metabolic adaptations, enzyme regulation, and therapeutic efficacy in preclinical models. Teaching: Responsible for microbiology courses, virology lectures, and curriculum development in medical programs. Supervises project work in the BMA program. Labs/Teams: Directs her research group, collaborating on projects involving nucleoside kinase expression, mitochondrial dysfunction, and drug development.

Maria Masucciمشاهده پروفایل

استاد

• Cell Biology
• Immunology
• Microbiology
• +۳ مورد دیگر

Maria Masucci is a Senior Professor in the Department of Cell and Molecular Biology at Karolinska Institutet. She leads the Molecular Mechanisms of Viral Oncogenesis research group, focusing on understanding how tumor viruses, particularly Epstein-Barr virus (EBV), manipulate host cellular pathways to drive oncogenesis. Her work emphasizes viral interference with the ubiquitin-proteasome system and autophagy mechanisms. Education: Docent in 1988 from Karolinska Institutet. Research spans over three decades, with a focus on viral oncogenesis, cellular signaling, and genomic instability. Key areas include EBV's role in lymphoma and nasopharyngeal carcinoma, and the interplay between viruses and host cell stress responses. Research Interests: Epstein-Barr virus pathogenesis and oncogenesis Ubiquitin-proteasome system and viral deconjugases Autophagy regulation and stress responses Genomic instability in viral infections Awards and Grants: Recipient of the 2021 Silver Medal. Secured grants from the Swedish Cancer Society and other institutions for viral oncogenesis research. Collaborates internationally, including with the Ming Wai Lau Centre for Reparative Medicine in Hong Kong. Labs/Teams: Head of the Molecular Mechanisms of Viral Oncogenesis group, which investigates viral strategies to reprogram host cells. Active in mentoring postdoctoral researchers like Jiangnan Liu and doctoral students like Bin Zhao.