جست‌وجوی استاد و پژوهشگر

Yi-Ling Chenمشاهده پروفایل

پژوهشگر ارشد

• Immunology
• T cell Biology
• Lipid Immunology
• +۳ مورد دیگر

Yi-Ling Chen, DPhil, is a Career Development Fellow at the Nuffield Department of Medicine, University of Oxford, where she leads the Chen Group dedicated to lipid-mediated T cell immunity research. Research Focus: Her work centers on Immunology and T cell Biology, specifically investigating lipid-reactive T cells in immune regulation, tissue homeostasis, and microbial defense. She employs high-dimensional proteotranscriptomics, T cell clonality analysis, and human immune organoid approaches to uncover molecular mechanisms for inflammatory and infectious disease interventions. Key interests include: Lipid antigen presentation via CD1 molecules T cell responses in psoriasis and skin inflammation Host-pathogen interactions with Group A Streptococcus and Staphylococcus aureus Translational applications for immune-mediated conditions Publication Trends: Analysis of her 15 most recent publications (2020-2024) reveals consistent focus on CD1-mediated lipid antigen presentation across infectious diseases (dengue, COVID-19, bacterial infections) and inflammatory conditions (psoriasis). Her work bridges molecular immunology with clinical applications, featuring in journals like Nature Immunology , Cell , and Science Immunology , with emphasis on therapeutic target discovery. Laboratory: The Chen Group operates within Oxford's Nuffield Department of Medicine, utilizing advanced immunological techniques to study T cell immunity in human disease contexts.

Kari Alitaloمشاهده پروفایل

استاد

• Cancer Biology
• Angiogenesis
• Lymphangiogenesis
• +۵ مورد دیگر

Kari Alitalo is an Academy Professor and Research Director at HUS Radiology and Pathology, University of Helsinki. He serves as a Supervisor in the Doctoral Programme in Integrative Life Science and the Doctoral Programme in Biomedicine. Alitalo directs the CAN-PRO - Translational Cancer Medicine Program and has led the Cancer Biology Research Programme at the University of Helsinki since 1999. His research primarily focuses on blood and lymphatic vessel growth factors with applications in cancer treatment and cardiovascular diseases. Alitalo's work spans angiogenesis, lymphangiogenesis, molecular biology, and translational medicine. His research group has made significant contributions to understanding vascular endothelial growth factors and their therapeutic applications. Alitalo's publication record shows consistent productivity with approximately 670 research outputs. His recent work (2023-2025) demonstrates continued focus on lymphatic system biology, vascular growth factors, and their therapeutic applications in cancer and cardiovascular diseases. The publications reveal a strong emphasis on molecular mechanisms of lymphangiogenesis, tumor angiogenesis, and potential therapeutic interventions. A.I. Virtanen Prize (2013) Biomedicum Helsinki lecture and Medal (2010) Eric K Fernström Foundation's Nordic Prize (2005) Finnish Science Prize (2013) Louis-Jeantet Prize For Medicine (2006) Professor Alitalo has supervised numerous doctoral students, with 52 dissertation supervisor or co-supervisor activities documented. He currently leads multiple active research projects including Cancer Foundation 2025/Alitalo, Biocenter Finland FIRI2023, and Juselius 2023-2026. His research group continues to explore vascular biology with significant implications for cancer treatment and cardiovascular medicine.

Mariaelena Pierobonمشاهده پروفایل

دانشیار

• Biomedical Research
• Medical Proteomics
• Precision Medicine
• +۳ مورد دیگر

Mariaelena Pierobon is an Associate Professor at George Mason University's School of Systems Biology, affiliated with the Institute for Advanced Biomedical Research and the Center for Applied Proteomics and Molecular Medicine (CAPMM). Her research focuses on precision medicine for cancer patients, integrating translational studies and clinical trials with emphasis on metastatic disease and tumor microenvironment analysis. MD, University of Padova (Italy), School of Medicine MPH, George Mason University Her work leverages in vitro models and patient-derived specimens with state-of-the-art technologies to explore cancer dynamics and develop tailored therapies. Recent projects include proteogenomic profiling of breast and ovarian tumors, KRAS mutation targeting, and spatial heterogeneity mapping in gynecologic cancers. Scientific trends in her publications include precision oncology, signaling pathway inhibition in KRAS-mutant cancers, tumor microenvironment analysis, and multi-omic diagnostics for therapeutic response prediction. Fulbright Scholar (2019) Pierobon collaborates with clinical teams using reverse phase protein arrays (RPPA) and laser capture microdissection to dissect molecular mechanisms in pancreatic, breast, and ovarian cancers. Her lab contributes to databases like the Side-Out Foundation Metastatic Breast Cancer portal for open-access multi-omic research.

Jessica D. Rosardaمشاهده پروفایل

استادیار

• Cellular Stress
• Signal Transduction
• Chemical Biology
• +۵ مورد دیگر

Jessica D. Rosarda PhD is an Assistant Professor in the Department of Anatomy, Physiology and Genetics at the Uniformed Services University (USU) of the Health Sciences School of Medicine in Bethesda, MD. She leads a research laboratory focused on cellular stress mechanisms in military-relevant disorders. PhD in Chemical and Biological Sciences, The Scripps Research Institute (2023) MSc in Pharmacy, University of Florida (2013) BSc in Biology, Washington and Lee University (2010) Dr. Rosarda's research centers on cellular stress response pathways, particularly how cells respond to stress through signaling mechanisms that can either protect or damage tissues. Her work spans chemical biology, molecular medicine, neuroscience, and molecular/cell biology with a focus on proteostasis, unfolded protein response, and stress signaling dynamics in disease contexts. She investigates how imbalances in these pathways contribute to conditions ranging from retinal degeneration to traumatic brain injury, with particular relevance to military medicine. Analysis of Dr. Rosarda's publication record reveals a strong focus on stress response pathways, particularly the unfolded protein response and integrated stress response. Her work demonstrates how perturbations in proteostasis contribute to diverse pathologies including neurodegeneration, amyloidosis, and inflammatory conditions. She employs chemical biology approaches to develop therapeutic strategies targeting these pathways, with several publications on pharmacological modulators of stress responses. Dr. Rosarda maintains an active research program with numerous publications in high-impact journals including Nature Communications, Cell Chemical Biology, and ACS Chemical Biology. Her work frequently involves collaborations with the Wiseman laboratory and other researchers in the fields of proteostasis and stress response. Dr. Rosarda's laboratory at USU focuses on defining stress pathway signaling dynamics in military-relevant disorders, determining the metabolic factors that govern these stress responses, and identifying novel approaches for resolving toxic stress involved in both acute and chronic conditions.

Filippo Vegliaمشاهده پروفایل

استادیار

• Cancer Immunology
• Myeloid Cell Biology
• Tumor Metabolism
• +۴ مورد دیگر

Filippo Veglia, Ph.D., is an Assistant Professor at The Wistar Institute, where he leads research in the Genome Regulation and Cell Signaling Program within the Ellen and Ronald Caplan Cancer Center. He returned to Wistar in December 2023 after serving as an Assistant Member at Moffitt Cancer Center in the Department of Immuno-Oncology and Neuro-Oncology Program from 2020-2023. Dr. Veglia is an expert in myeloid cell biology, cancer immunology, and tumor metabolism. His research focuses on understanding how the tumor microenvironment, particularly in glioblastoma (the deadliest form of brain cancer), reprograms the metabolism and function of myeloid cells to create an immunosuppressive environment that helps tumors evade immune responses. His lab has made significant discoveries regarding histone lactylation and its role in promoting immunosuppressive activity in tumor-associated macrophages. Dr. Veglia earned his Ph.D. in Immunology and Applied Biotechnology from Tor Vergata University in Rome, Italy, and completed his postdoctoral training in the lab of Dr. Dmitry Gabrilovich at The Wistar Institute. His research has been published in high-impact journals including Nature, Immunity, and Cancer Discovery. His recent publications demonstrate how glucose metabolism in tumor-associated macrophages drives histone lactylation, which promotes the expression of immunosuppressive molecules like IL-10. His work has revealed potential therapeutic targets such as PERK that could disrupt this immunosuppressive pathway and enhance immunotherapy effectiveness against brain cancer. Dr. Veglia's laboratory includes Staff Scientist Alessandra De Leo, Ph.D., Postdoctoral Fellows Barbara Peixoto, Ph.D. and Alessio Ugolini, Ph.D., and Predoctoral Trainee Filippo Badii. His research has been supported by grants from The Ben & Catherine Ivy Foundation, The National Institute of Neurological Disorders and Stroke, and the American Cancer Society.

• Physiology
• Metabolic Biochemistry
• Nutrition & Dietetics
• +۸ مورد دیگر

Dr. Vini Fernandes Cruzat is a Lecturer in Human Anatomy and Physiology at Southern Cross University’s Faculty of Health. He holds a PhD in Biomedical Science/Nutritional Biochemistry from the University of São Paulo and is a registered Nutritionist in Australia. His roles include Chair of the Queensland group of the Nutrition Society of Australia and Adjunct Senior Researcher at Griffith University. Academic Background: Bachelor in Exercise and Sport Science (Lutheran University of Brazil) Graduate Certificate in Learning and Teaching (Torrens University Australia) Master of Science in Nutritional Biochemistry (University of São Paulo) Dr. Cruzat’s research focuses on the metabolic, antioxidant, and anti-inflammatory effects of nutrient supplementation, particularly amino acids like glutamine, arginine, and leucine, as well as vitamin D and bioactive compounds from spent coffee grounds. He investigates cellular mechanisms in diabetes associated with obesity, emphasizing oxidative stress, insulin resistance, and heat shock protein pathways. His recent work explores the therapeutic potential of coffee byproducts and vitamin D in metabolic disorders. His publications over the past five years highlight a consistent focus on amino acid metabolism, oxidative stress in diabetes, and the intersection of nutrition/exercise with inflammation. Key trends include molecular studies of beta-cell dysfunction, clinical trials on supplementation, and applications of coffee compounds in functional food development. Dr. Cruzat has supervised 3 PhD, 6 MSc, and 5 Honours students across Australian and international institutions. He teaches human anatomy, physiology, and metabolic biochemistry and contributes to research networks in diabetes and exercise physiology.

• Geriatrics
• Psychiatry
• Neurology
• +۵ مورد دیگر

Jason Jalil serves as an HS Assistant Clinical Professor in the Department of Psychiatry and Biobehavioral Sciences at the David Geffen School of Medicine, University of California, Los Angeles. His academic career demonstrates a significant research evolution spanning oncology immunology and geriatric psychiatry. His primary research domains include: Geriatric psychiatry and dementia care Brain health in aging populations Cancer immunotherapy (particularly melanoma) CTLA4 blockade mechanisms Digital technology's neurological impacts Polypharmacy management in elderly patients Dr. Jalil's publication history reveals a strategic research transition from 2008-2013 cancer immunology work with the Ribas laboratory to 2019-2022 geriatric psychiatry research. This shift reflects both personal academic development and broader trends in medical research priorities. His early work focused on tumor immunology mechanisms, while recent publications address practical clinical challenges in dementia care and cognitive health maintenance. He maintains active collaborations across UCLA departments, particularly with: Dr. Antoni Ribas (Jonsson Comprehensive Cancer Center) Dr. Susan Bookheimer (neuroimaging expert) Dr. Pauline Wu (geriatric psychiatry) Dr. Stephen Chen (aging research) His research has generated significant academic impact, with publications referenced in patents, clinical guidelines, news media, and social platforms. The 2020 paper on digital technology's brain health consequences has been particularly influential, accumulating 62 PubMed Central citations and substantial social media attention.

Arnold I. Chinمشاهده پروفایل

استاد

• Urologic Oncology
• Renal Transplantation
• Cancer Stem Cell Research
• +۳ مورد دیگر

Dr. Arnold I. Chin is a Professor of Urology and Medical Director of Urology-Westwood at the David Geffen School of Medicine at UCLA. He completed both his MD and PhD at UCLA and completed his urology residency training there as well. His clinical expertise spans urologic oncology and renal transplantation, with specialization in open, laparoscopic, and robotic-assisted surgeries for bladder, kidney, and prostate cancer patients. Dr. Chin's educational background includes: MD, UCLA School of Medicine, 2003 PhD, UCLA, 2002 Internship in Surgery, UCLA School of Medicine, 2004 Residency in Urology, UCLA School of Medicine, 2009 Dr. Chin's research focuses on understanding cancer differentiation and its interplay with the tumor microenvironment. His laboratory investigates molecular mechanisms in programming tumor-infiltrating lymphocytes and mechanisms controlling development and differentiation of cancer stem cells. His work aims to develop novel therapeutic targets, immune-based platforms, and stem cell-directed therapies against cancer. He is affiliated with the Broad Stem Cell Research Center, Tumor Immunology Program Area, and Genitourinary Oncology Program Area of the Jonsson Comprehensive Cancer Center. His recent research has centered on bladder cancer, prostate cancer, renal cell carcinoma, and neuroendocrine carcinomas, with emphasis on tumor microenvironment, immunotherapy approaches, and molecular targets for cancer treatment. Dr. Chin has received several prestigious awards: Super Doctors® Southern California, 2022-2025 Super Doctors® Southern California Rising Stars 2018 STOP Cancer Research Career Development Award 2010 American Association of Cancer Research Career Development Award for Translational Cancer Research 2010 Dr. Chin is actively involved in mentoring students and research fellows in his laboratory, guiding them in cutting-edge cancer research. His work has been supported by various grants from organizations including STOP Cancer and the American Association of Cancer Research. He is also involved in clinical trials related to urologic cancers. Dr. Chin leads a translational research laboratory focused on tumor microenvironment in prostate and bladder cancer, using a combination of animal models, human reconstitution systems, and primary tumor and hematopoietic cells. His team is investigating molecular mechanisms in programming tumor-infiltrating lymphocytes and the development and differentiation of cancer stem cells.

John H. Stewart, IVمشاهده پروفایل

استاد

• Surgical Oncology
• Cancer Immunotherapy
• Clinical Trials
• +۵ مورد دیگر

John H. Stewart, IV serves as Chair of the Department of Surgery and Associate Dean of Oncology Programs at Morehouse School of Medicine, where he is a board-certified surgeon by the American Board of Surgery specializing in Surgical Oncology. His educational trajectory includes: BS in Zoology (Honors) from Louisiana Tech University MD from Howard University College of Medicine MBA from Wake Forest University General Surgery residencies at Temple University and Vanderbilt University Fellowship in Tumor Immunotherapy & Surgical Oncology at the National Institutes of Health Dr. Stewart's research program bridges Surgical Oncology, Cancer Immunotherapy, and Healthcare Disparities through innovative work in developmental oncoimmunotherapeutics and AI-driven healthcare delivery systems. He critically examines healthcare finance, policy, and operations to optimize cancer therapy access for underserved populations, with emphasis on structural barriers in treatment delivery. His publication record shows evolving focus from cytoreductive surgery techniques (2009-2012) toward contemporary immunometabolic reprogramming (2022-2023), tumor microenvironment dynamics, and bias analysis in colorectal cancer management. Recent work explores obesity-leukemia connections and cervical cancer immunology. Accolades include the 2023 Howard University Distinguished Alumni Award, University of Illinois Presidential Scholar (2018-2022), NCI Cancer Clinical Investigator Leadership Award (2013-2015), and consistent recognition in Best Doctors in America and US News Top Doctors listings. As academic administrator, Dr. Stewart directs surgical oncology programs while advancing health equity initiatives. His NCI award reflects substantial clinical investigation leadership, though specific grant details and student mentorship aren't documented in source materials. Based at Grady Memorial Hospital in Atlanta, his work integrates clinical practice, administrative leadership, and health disparities research to transform cancer care in marginalized communities through surgical innovation and policy reform.

Jane E. Cavanaughمشاهده پروفایل

استادیار

• Neurobiology of Aging
• Cancer Biology
• Neurodegenerative Diseases
• +۳ مورد دیگر

Jane E. Cavanaugh, Ph.D., is an Assistant Professor in the Division of Pharmaceutical Sciences at Duquesne University's School of Pharmacy and an Adjunct Assistant Professor in the Department of Pharmacology at the University of Pittsburgh. She received her Ph.D. in Pharmacology from Pennsylvania State College of Medicine (1997) and a B.A. in Chemistry from Franklin & Marshall College (1992). Her research focuses on the neurobiology and cancer biology of aging, specifically investigating intracellular signaling pathways (e.g., ERK5) that influence cell proliferation and survival in age-related pathologies. Key areas include: Neurodegenerative diseases (Alzheimer's, Parkinson's) Breast cancer mechanisms in aging Interventions using natural compounds (e.g., resveratrol) Motor deficit reversal strategies Her publications (1993–2011) predominantly explore neuroscience and pharmacology, with recurring themes in ERK signaling, neuroprotection, dopaminergic systems, and aging models. Recent work emphasizes therapeutic interventions for neurodegeneration and cancer. Awards & Honors: National Institute on Aging Career Award (K01) Travel Fellowship for Aging Research Graduate Commencement Speaker at Penn State Grants & Funding: She directs multiple projects, including a Duquesne University-funded study on intranasal L-Dopa delivery for CNS disorders and an NIA-supported investigation into ERK5's role in dopaminergic neuron survival. Other grants target breast cancer pathways and age-related motor deficits. Dr. Cavanaugh teaches courses in Human Physiology, Pathology, Pharmacology, and Toxicology for Duquesne's PharmD and graduate programs, and directs a laboratory focused on aging-related signaling pathways.

Poul Henning Jensenمشاهده پروفایل

استاد

• Neurobiology
• Parkinson's Disease
• Synucleinopathies
• +۴ مورد دیگر

Poul Henning Jensen is a full Professor at Aarhus University , affiliated with both the Department of Biomedicine (Skou-building) and the Department of Molecular Biology and Genetics (Neurobiology section). Research Interests : Neurobiology of synucleinopathies Molecular mechanisms in Parkinson's disease Protein aggregation and propagation Calcium signaling in neurodegeneration Neuroinflammatory responses Scientific Activities : His work focuses on α-synuclein biology, covering structural analysis, aggregation pathways, and their pathological consequences. Recent studies include novel detection methods for early α-synuclein pathology mechanisms of neurotoxicity sex-specific neuroprotective factors and protein interaction networks in disease models . Scientific Awards : Recipient of at least one significant research prize Collaborations : Works with international teams on clinical trials targeting α-synuclein and coordinates multiple studies on neurodegenerative disease mechanisms.

Martin Lohseمشاهده پروفایل

استاد

• Physiology of receptors
• Pharmacology of receptors
• Molecular biology of receptor function
• +۶ مورد دیگر

Martin Lohse is a Professor for Pharmacology and Toxicology at the University of Würzburg since 1993. He currently serves as Vice President for Research (since 2009) and Executive Director for Graduate Schools (since 2003). His career includes leadership roles at the Rudolf-Virchow-Center for Experimental Biomedicine and foundational research at institutions like Duke University and the Max-Planck-Institute for Biochemistry. Research Focus: Lohse's work centers on receptor physiology and pharmacology, particularly the molecular biology of G-protein-coupled receptors (GPCRs), intracellular signaling, desensitization, and advanced fluorescence microscopy techniques. His studies explore receptor dynamics in cardiac systems and signaling persistence through internalized receptors. Scientific Awards: Gottfried Wilhelm Leibniz-Prize (1999) Ernst-Jung-Prize for Medicine (2000) ERC Advanced Investigator Grant (2008) Bavarian Order of Merit (2006) German Federal Cross of Merit (2002) Leadership & Grants: He initiated the Collaborative Research Center 478 on Regulatory Membrane Proteins and chairs the Rudolf-Virchow-Center funded by the German Research Foundation. His work has secured significant grants, including the 2008 ERC Advanced Investigator Grant.

Li Zhangمشاهده پروفایل

استاد

• Molecular Biology
• Cell Biology
• Genomics
• +۴ مورد دیگر

Dr. Li Zhang is a Professor and Head of the Department of Biological Sciences at the University of Texas at Dallas (UT Dallas), holding the Cecil H. and Ida Green Distinguished Chair in Systems Biology. He has held academic positions at Columbia University, New York University, and MIT. His research focuses on heme signaling, lung cancer, Alzheimer’s disease, and molecular mechanisms of cellular metabolism. He has secured funding from CPRIT and NIH, including a CPRIT grant for optimizing therapeutic strategies against lung cancer. Education: Postdoc (MIT, 1995), Ph.D. in Biochemistry (UCLA, 1990), B.S. in Chemistry (Zhongshan University, China, 1984). Research interests include heme’s role in cancer progression, Alzheimer’s pathogenesis, and oxygen signaling. His lab has published extensively on heme regulation in tumors and neuronal systems, with key findings on heme sequestration as a therapeutic strategy. Notable publications in Cancer Research and Alzheimer's & Dementia highlight his contributions. Awards include the Cecil H. and Ida Green Chair, Monique Weill-Caulier Scholarship, and recognition as a top-cited author in molecular biology. He has co-founded a company to commercialize IP from his research on heme-based therapies.

• Vascular Biology
• Renal Physiology
• Hypertension Pathophysiology
• +۳ مورد دیگر

Jonathan Nelson is an Assistant Professor in the Division of Nephrology & Hypertension at the University of Southern California (USC) Keck School of Medicine. He holds a PhD in Molecular and Medical Genetics from Oregon Health & Science University (OHSU), where he also completed clinical training in Anesthesiology, Cardiovascular Medicine, and Nephrology. His research focuses on vascular biology and the renin-angiotensin system's role in kidney microvasculature regulation, with funding from the NIH, American Heart Association, and Collins Medical Trust. Education: Bachelor’s degree in Biochemistry, University of Washington PhD in Molecular and Medical Genetics, Oregon Health & Science University Research interests include understanding how angiotensin II signaling impacts kidney and cardiovascular health, particularly in hypertension and microvascular dysfunction. His work bridges molecular mechanisms with clinical implications, leveraging mouse models to study renal physiology and disease pathways. Publications highlight his focus on renal transporters, endothelial signaling, and angiotensin system dynamics. Recent work explores ACE2 filtration in kidneys and COP9 signalosome roles in renal injury. Grants & Funding: NIH, American Heart Association, Collins Medical Trust. Labs/Teams: His research is conducted within the USC Keck School of Medicine’s Division of Nephrology & Hypertension, collaborating with cardiovascular and renal biology experts.

• Cancer Biology
• Molecular Medicine
• RNA Splicing
• +۵ مورد دیگر

Sita Reddy is an Associate Professor of Cancer Biology at the University of Southern California (USC) and Co-Director of the Molecular Medicine PhD Program. Her research focuses on molecular mechanisms underlying genetic disorders, cellular aging, and cancer biology. Key areas include RNA splicing regulation by Muscleblind proteins, lamin A dysfunction, telomere biology, and progeroid syndromes. Her work integrates studies on myotonic dystrophy, telomere maintenance, and gene expression abnormalities. Notable contributions include unraveling the role of MBNL1 in RNA processing and identifying FOXQ1 as a mediator of lamin A-related pathologies. She also investigates how altered RNA metabolism and protein interactions drive disease progression in genetic disorders. Publications highlight her exploration of telomeric DNA processing by the Werner syndrome protein, the impact of prelamin A variants on cellular health, and the interplay between nuclear structure and aging. Her research bridges basic molecular biology with translational insights into aging-related diseases and cancer. Dr. Reddy’s scientific contributions are reflected in her extensive peer-reviewed publications, with a focus on high-impact journals like Cell , EMBO Journal , and Proceedings of the National Academy of Sciences .