معرفی
Mariaelena Pierobon is an Associate Professor at George Mason University's School of Systems Biology, affiliated with the Institute for Advanced Biomedical Research and the Center for Applied Proteomics and Molecular Medicine (CAPMM). Her research focuses on precision medicine for cancer patients, integrating translational studies and clinical trials with emphasis on metastatic disease and tumor microenvironment analysis.
- MD, University of Padova (Italy), School of Medicine
- MPH, George Mason University
Her work leverages in vitro models and patient-derived specimens with state-of-the-art technologies to explore cancer dynamics and develop tailored therapies. Recent projects include proteogenomic profiling of breast and ovarian tumors, KRAS mutation targeting, and spatial heterogeneity mapping in gynecologic cancers.
Scientific trends in her publications include precision oncology, signaling pathway inhibition in KRAS-mutant cancers, tumor microenvironment analysis, and multi-omic diagnostics for therapeutic response prediction.
- Fulbright Scholar (2019)
Pierobon collaborates with clinical teams using reverse phase protein arrays (RPPA) and laser capture microdissection to dissect molecular mechanisms in pancreatic, breast, and ovarian cancers. Her lab contributes to databases like the Side-Out Foundation Metastatic Breast Cancer portal for open-access multi-omic research.
