جست‌وجوی استاد و پژوهشگر

Joao Pereiraمشاهده پروفایل

دانشیار

• Immunology
• Hematopoiesis
• Hematopoietic Stem Cells
• +۴ مورد دیگر

Dr. João P. Pereira is an Associate Professor of Immunobiology at Yale University, affiliated with the Yale Cancer Center and Yale Stem Cell Center. He holds academic roles in the Yale School of Medicine and leads the Pereira Lab, focusing on B lymphocyte development, hematopoietic stem cell niches, and immune cell migration. His research explores how mesenchymal stem cells and cytokines regulate blood cell formation and immune responses. Education: BSc in Microbiology (Universidade Católica Portuguesa, 1996), MSc in Biotechnology (DeMontfort University, 1997), PhD in Immunology (Universidade do Porto, 2004) with postdoctoral training at UCSF under Dr. Jason Cyster. Research Interests: Dr. Pereira’s work centers on three main areas: 1) Bone marrow stem cell niches and their role in hematopoiesis and plasma cell maintenance. 2) B cell development dynamics in the bone marrow, particularly interactions between B cell precursors and mesenchymal progenitors. 3) Chemoattractant signaling in B cell homeostasis, using pertussis toxin to study receptor-mediated effects. Publications: Recent work includes studies on fetal liver hematopoietic niches (2025), B lymphopoiesis regulation (2024), and leukemic cell-mesenchymal interactions (2023). His research spans immunology, stem cell biology, and inflammatory pathways. Labs/Teams: The Pereira Lab investigates B lymphocyte biology and immune cell migration using advanced microscopy and genetic tools. Collaborations include work with Richard Flavell, Akiko Iwasaki, and David Hafler on projects involving immunological pathways and disease models.

• Peptide Self-Assembly
• Amyloid Peptides
• Amyloid-Inspired Materials
• +۳ مورد دیگر

Bradley L. Nilsson is a Professor of Chemistry and Director of the Materials Science Program at the University of Rochester's School of Arts & Sciences. He holds a PhD from the University of Wisconsin, Madison (2003). His research focuses on peptide self-assembly, particularly the study of amyloid peptides and their applications in functional materials,生物医药, and energy. Key projects include developing peptide-based hydrogels for tissue engineering, anti-HIV microbicides, and supramolecular materials derived from phenylalanine derivatives. His work also explores the noncovalent interactions driving self-assembly and their biomedical applications. Research interests span peptide self-assembly mechanisms, amyloid-inspired materials, and applications in drug delivery and nanotechnology. Notable contributions include the development of cyclic amphipathic peptides for siRNA delivery and the design of amyloid-mimetic hydrogels. His recent studies investigate quantum dot biomimetics for neuroinflammation research and the role of sequence patterns in peptide assembly. No scientific awards are explicitly listed in the provided text. His research has been supported by collaborative grants focusing on multi-component peptide nanofibrils and supramolecular materials. He leads the Materials Science Program, fostering interdisciplinary research in biomaterials and nanotechnology.

Sophie C. Coxمشاهده پروفایل

دانشیار

• Medical Device Innovation
• Biomaterials Science
• Additive Manufacturing
• +۳ مورد دیگر

Dr. Sophie C. Cox is an Associate Professor in Healthcare Technologies at the University of Birmingham's School of Chemical Engineering, affiliated with the Healthcare Technologies Institute (HTI). Her research focuses on innovating medical devices through advanced manufacturing and biomaterials to improve patient outcomes. She holds a PhD in Biomedical Engineering (2013) and BEng in Engineering (2010) from the University of Warwick. Her work integrates chemical synthesis, additive manufacturing, and formulation engineering to address clinical challenges such as infection prevention and tissue regeneration. Dr. Cox's research interests span biomaterials science, additive manufacturing, and translational healthcare technologies. She collaborates across disciplines including chemical engineering, biomedical science, and computer science through the HTI. Her team develops customized implants, anti-infective medical devices, and therapies leveraging cell-derived nanoparticles. She leads undergraduate and postgraduate teaching in Chemical Engineering and supervises PhD/MSc students. Her work emphasizes collaboration with clinicians and industry to accelerate research into clinical applications. Current projects include modifying implants to reduce infection risks, designing controlled therapeutic delivery systems, and analyzing bone-cartilage interfaces using advanced imaging techniques. Dr. Cox chairs the Postgraduate Student Staff Committee and actively mentors early-career researchers. Lab affiliations include the Tissue Regeneration and Interface Lab (TRAILab) and the HTI. She is also engaged in expanding research opportunities via collaborations nationally and internationally.

• Orthopaedic Surgery
• Hip Disorders
• Pain Management
• +۴ مورد دیگر

Jens Kristinsson serves as a Chief Physician ( Ledende overlæge ) at Aalborg University Hospital within The Faculty of Medicine's Department of Orthopaedic Surgery. He maintains an active clinical and research profile focused on complex orthopaedic conditions, particularly those affecting the hip and knee joints. His primary research interests include: Hip disorders and pain management Osteoid osteoma and bone tumors Fracture treatment in children and adolescents Rehabilitation engineering Greater trochanteric pain syndrome Intraneural ganglion cysts Kristinsson's scholarly work demonstrates a strong commitment to both clinical innovation and patient-centered outcomes. His research portfolio spans qualitative assessment of patient experiences, surgical technique development for complex joint disorders, and validation of clinical assessment instruments. Recent publications reveal particular expertise in managing challenging hip pathologies involving both bony and soft tissue structures, as well as innovative approaches to pediatric orthopaedic trauma. His work on the Danish translation of the VISA-G assessment tool highlights his dedication to improving clinical evaluation methods in his specialty. His publications have received citations in scholarly literature and some media attention, indicating recognition within the orthopaedic community. Kristinsson frequently collaborates with colleagues including H.P. Jensen, R. Elsoe, and others across multiple institutions, demonstrating active participation in the broader research network.

Ilyas Khanمشاهده پروفایل

دانشیار

• Cartilage biology
• Stem cells and progenitor cells
• Tissue engineering
• +۵ مورد دیگر

Dr. Ilyas Khan is an Associate Professor in Biomedical Sciences at Swansea University's Medical School. His research focuses on regenerative medicine and tissue engineering, particularly in developing cartilage repair solutions for joint diseases like osteoarthritis. He leads a lab investigating stem cells' role in cartilage development, 3D tissue engineering, and translational clinical applications with NHS collaboration. Dr. Khan holds a PhD from Imperial College London (1996–2000) and has secured significant grants, including a £1.3M project (2014–2020) with Utrecht University. He teaches modules on regenerative medicine and supervises postgraduate students in areas like BMP9-induced cartilage maturation and synthetic bone allografts. His work bridges basic science and clinical translation, emphasizing global research impact. Teaching includes undergraduate courses on regenerative medicine and advanced nanomedicine modules. Collaborations span European and global institutions. Key research themes include stem cell biology, cartilage progenitor cells, and bioprinting. Scientific output includes over 20 peer-reviewed articles, with recent focus on BMP9 signaling and 3D scaffold technologies.

Enrico Dall'Araمشاهده پروفایل

استاد

• Biomechanics
• Computational Modeling in Medicine
• Musculoskeletal Tissue Mechanics
• +۶ مورد دیگر

Professor Enrico Dall'Ara is a leading figure in musculoskeletal biomechanics at the University of Sheffield , where he holds the Professorship of Musculoskeletal Biomechanics since 2024. He directs the Skelet.Al Laboratories , serves as Research Director for Insigneo's Computational Modelling in Medicine theme, and leads the Non-Clinical Task Force in the Avicenna Alliance. Education: PhD in Biomechanics (Vienna), MSc Mechanical Engineering (Bologna) Current Roles: President of European Society of Biomechanics, Deputy Head of IMSB Research Group Research Focus: Subject-specific computational models for bone strength prediction, fracture risk assessment, and mechanobiological studies in preclinical/clinical settings. Key applications include osteoporosis , osteoarthritis , and vertebral metastases , integrating imaging , experimental , and computational methods . Recent Article Trends: His computational work spans finite element modeling , digital volume correlation , machine learning in segmentation , and multi-scale adaptation studies , validated through microCT , synchrotron tomography , and MR imaging across mouse models and human specimens . Scientific Awards & Leadership: President, European Society of Biomechanics (2024) Director, Skelet.Al Laboratories (2020) Research Director, Insigneo (2021) Council Member, Avicenna Alliance (2023) Editorial roles in Journal of Mechanical Behaviour and Frontiers in Bioengineering Advising & Grants: Mentors 14+ PhD students across international institutions. Secured £2.6M+ in grants including EPSRC Virtual Human Twin (£1.74M), Horizon Europe METASTRA (£773k), and EUROSTARS projects. Collaborates with EPSRC, Horizon2020, and AO Spine.

Gwendolen Reillyمشاهده پروفایل

استاد

• Musculoskeletal Bioengineering
• Bone Tissue Engineering
• Cell Mechanobiology
• +۴ مورد دیگر

Professor Gwendolen Reilly is a distinguished academic in the School of Chemical, Materials and Biological Engineering at the University of Sheffield, where she serves as Professor of Musculoskeletal Bioengineering, School EDI lead, and Co-chair of the staff Women's Network. She has been a member of academic staff since 2004 and co-directs the CDT in Advanced Biomedical Materials. Her research program focuses on musculoskeletal bioengineering, with three primary interconnected themes: bone tissue engineering, musculoskeletal cell mechanobiology, and orthopaedic biomaterials. Reilly's work investigates how skeletal cells respond to mechanical stimuli, the interactions between precursor bone cells and biomaterial substrates, and the development of improved methods for repairing skeletal tissues including bone, tendon, and cartilage. She employs various bioreactors (including collaborations with ElectroForce systems) to examine mechanical stimuli such as dynamic compression, stretch, and fluid flow-induced shear stresses. Her publication record shows consistent high-impact research output through 2024, with recent work focusing on polyHIPE scaffolds, nanoparticle-doped biomaterials, collagen structure analysis in bone disorders, and craniofacial bone defect repair. Her research demonstrates strong interdisciplinary collaboration, particularly with Frederik Claeyssens and colleagues across the university. Fellow of the Higher Education Academy Alice L Jee Young Investigator Award at the 37th International Sun Valley Workshop on Skeletal Biology Reilly maintains active professional engagement as editorial board member for several journals including European Cells and Materials, PLoS ONE, Heliyon, and Frontiers in Bioengineering. She serves on panels for Marie Skłodowska-Curie Fellowships and is a member of multiple professional societies including the American Society of Bone and Mineral Research, Orthopaedic Research Society, and Tissue Engineering and Regenerative Medicine International Society.

Allison Pettitمشاهده پروفایل

استاد

• Immunology
• Rheumatology
• Cancer Biology
• +۴ مورد دیگر

Professor Allison Pettit is a leading academic at The University of Queensland (UQ), serving as Director of the Mater Research Institute - UQ and leading the Bones and Immunology Research Group. Her roles include Director of Biomedical Research at Mater Research and affiliation with the Centre for Extracellular Vesicle Nanomedicine. She holds a Bachelor (Honours) of Science (Advanced) from Griffith University and a Doctor of Philosophy from UQ. Her research focuses on immunology, rheumatology, cancer biology, haematology, and bone biology. Key discoveries include the identification of osteal macrophages (osteomacs) and their roles in bone formation, bone regeneration, and hematopoietic stem cell niches. She has pioneered studies on macrophage fragmentation in single-cell analyses, impacting research methodologies. Professor Pettit’s work addresses bone fracture healing, osteoporosis, and the effects of cancer therapies on bone marrow. She has received awards such as the 2019 UQ Faculty of Medicine Leader of the Year and is a Fellow of the American Society of Bone and Mineral Research. Her research impacts span translational medicine, including collaborations with pharmaceutical companies. She actively supervises PhD candidates, with notable students like Dr. Lena Batoon and Dr. Alexander. Her grants include NHMRC and ARC funding for projects on macrophage biology and hematopoietic stem cell niches.

• Biomechanics
• Biomaterials
• 3D Printing
• +۳ مورد دیگر

Xiaoyu Du is a researcher at the Institute for Biomechanics at ETH Zürich , focusing on advanced biomaterials and 3D printing technologies for medical applications. Their work emphasizes orthopedic and spinal implant development using composite materials. Research Focus: 3D-printed scaffolds for bone regeneration, silicon nitride bioceramics, and patient-specific regenerative medicine. Key Contributions: Development of LEGO®-inspired modular implants, shock-absorbing composites, and microgel delivery systems for targeted tissue repair. Contact: Email xiaoyu.du@hest.ethz.ch for collaboration or inquiries.

Didier Dreauمشاهده پروفایل

استاد

• Cancer Biology
• Molecular Biology
• Immunology
• +۷ مورد دیگر

Didier Dreau is a Full Professor in the Department of Biological Sciences at the University of North Carolina at Charlotte (UNCC). He holds a Ph.D. in Molecular and Cell Biology (Immunology) from the College of Agriculture of Rennes, France, and has dedicated his career to understanding cancer metastasis, with a focus on melanoma and breast cancer. His research explores molecular mechanisms, vascular interactions, and immune responses in tumor progression. Bachelor in Physiology & Cell Biology, University of Rennes I (1988) Master in Molecular & Cell Biology, University Blaise Pascal (1990) Ph.D. in Molecular & Cell Biology (Immunology), College of Agriculture of Rennes (1994) Dr. Dreau’s laboratory investigates cancer metastasis through four key areas: Signaling (cytokine/chemokine interactions) , Anchoring and Growth of Metastases , Vascularization of Tumors , and Immune System Interactions . His work emphasizes inflammasomes in local inflammation and tumor microenvironment dynamics. Recent publications highlight advancements in chemokine heterodimerization to inhibit cancer migration, 3D organ miniaturization for drug discovery, and nano-based therapies for pancreatic cancer. His team employs murine models , electrospun biomaterials , and in vivo imaging to dissect metastatic processes. Scientific awards include: 2014 Outstanding Faculty Award 2014 Multicultural Academic Service Award 2020 CLAS Excellence in Teaching (Integration of Undergraduate Research) Dr. Dreau mentors graduate and honors students, including notable alumni like Khanh Nguyen (2021) and Yas Maghdouri-White (2014), and actively engages undergraduates in research projects. His lab alumni include postdoctoral fellows and graduate researchers who have contributed to understanding fibrosis , inflammation , and macrophage-tumor interactions .

Luke J. Mortensenمشاهده پروفایل

استادیار

• Cellular Therapeutics
• Regenerative Medicine
• Multiphoton Microscopy
• +۳ مورد دیگر

Luke J. Mortensen is an Assistant Professor at the University of Georgia, holding a joint appointment in the College of Agricultural and Environmental Sciences' Department of Animal and Dairy Science and the Regenerative Bioscience Center. His research focuses on developing next-generation cellular therapeutics and advanced imaging techniques to study musculoskeletal health and disease. He specializes in multiphoton microscopy, stem cell biology, and lipidomics, with applications in regenerative medicine and musculoskeletal disorders. Dr. Mortensen's work involves integrating imaging modalities with lipidomic analysis to evaluate mesenchymal stromal cell (MSC) potency, particularly in contexts like hypophosphatasia and volumetric muscle loss. His projects also explore novel contrast agents (e.g., perovskites) for in vivo imaging and adaptive optics to enhance deep-tissue visualization through bone. Recent studies address collagen organization defects, pro-regenerative inflammation, and mitochondrial dynamics in injured tissues. His research trends emphasize precision medicine approaches, combining engineering solutions (e.g., bioreactors for tendon tissue engineering) with molecular insights into immune modulation and tissue repair. Collaboration with the Regenerative Bioscience Center underscores his commitment to translational applications of stem cell therapies. No scientific awards are explicitly listed in the provided texts. His work is supported by grants focused on imaging technology development and regenerative medicine. He advises students in interdisciplinary projects at the intersection of engineering and biomedical sciences. Luke J. Mortensen is based at the iSTEM 1 facility, Room 2040G, in Athens, Georgia.

Steven Eppellمشاهده پروفایل

دانشیار

• Biomaterials Engineering
• Nanomechanics
• Collagen Fibril Mechanics
• +۵ مورد دیگر

Steven Eppell, PhD is an Associate Professor in the Department of Biomedical Engineering at Case Western Reserve University's Case School of Engineering. He also serves as Director of the Nanoscale Orthopedic Biomaterials Laboratory (NOBL). His academic career includes a PhD in Biomedical Engineering from Case Western Reserve University (1994) and a Bachelor of Arts in Physics from Carleton College (1984). Eppell's research focuses on bridging atomic to microscale measurements through advanced instrumentation and biomimetic strategies. Key areas include collagen fibril mechanics, biomaterial design for orthopedics, and nanoscale surface characterization using atomic force microscopy (AFM). His lab develops models to predict supramolecular assembly and investigates nanoscale constraints of natural bone/tendon for synthetic material creation. Recent work emphasizes synthetic bone substitutes, dental implant stabilization, and collagen-titanium interface engineering. Over 80 publications span biomaterials, nanomechanics, and medical applications with frequent collaborations in materials science and biophysics. His instrumentation innovations include AFM-based charge quantification methods and cantilever dynamics modeling.

• Mathematical Modeling
• Microfluidics
• Gene Regulatory Networks
• +۷ مورد دیگر

Claudiu Vasile Giuraniuc is a Lecturer in the School of Natural and Computing Sciences at the University of Aberdeen, where he has been actively contributing since 2010. His interdisciplinary research bridges physics, biology, and computational modeling, with a strong emphasis on microfluidics, gene regulatory networks, and medical image analysis. BSc in Physics, “Al.I. Cuza” University, Iasi, Romania MSc in Physics, Lille 1 University, France PhD in Physics, Katholieke Universiteit Leuven, Belgium (2006) His research focuses on mathematical modeling of biological systems , particularly in developmental biology and microbial pathogenesis. He applies microfluidics and lab-on-a-chip technologies to study cellular behavior under dynamic conditions, including chemical gradients and electrical stimulation. His work in gene regulatory networks and Wnt signaling has provided insights into embryogenesis and tissue development. Additionally, he contributes to orthopedic research through statistical shape modeling of the hip joint and its relation to osteoarthritis. The 15 most recent publications reflect a strong trend toward interdisciplinary systems biology , combining experimental microfluidics with computational modeling. Key themes include cell signaling dynamics , developmental morphogenesis , genetic regulation of bone shape , and synthetic biology applications . The work spans from fundamental physics-based models to translational biomedical research. Scientific contributions are recognized through publications in high-impact journals such as eLife , mBio , and Journal of Bone and Mineral Research . Notable collaborations include work with researchers in immunology, orthopedics, and synthetic biology. As a Principal Investigator, he has led projects such as Microfluidic tools for personalized medicine (NHS Endowment grant) and industry partnerships with ibidi® . He has also served as Co-Investigator on grants related to nanoparticle-embedded membranes and nerve-muscle co-cultures. He mentors research through collaborative projects, though no formal students are listed. His lab integrates microfluidic culture systems , mathematical modeling , and image analysis pipelines to study complex biological phenomena across scales.

David Nikolic-Patersonمشاهده پروفایل

استاد مدعو

• Chronic Kidney Disease
• Inflammation
• Fibrosis
• +۳ مورد دیگر

David Nikolic-Paterson is an Adjunct Professor of Medicine at Monash University's Monash Health Centre for Inflammatory Disease. He leads a research laboratory focused on mechanisms of inflammation and fibrosis in kidney disease and transplant rejection, with particular emphasis on signaling pathways in leukocytes, kidney cells, and fibroblasts. His work combines experimental models (human and animal) with clinical trials, including studies on ASK1 inhibitors for diabetic kidney disease. He has collaborated extensively with international researchers and pharmaceutical companies. Current research projects include engineering anti-fibrotic therapies for chronic kidney disease, dissecting cystogenic pathways in polycystic kidney disease, and developing human kidney organoid models to replace mouse studies. He has led or co-led 25+ research projects since 2009, securing funding for initiatives like biomarker identification for therapy response and improving outcomes in cardiac surgery-induced kidney injury. His publications (264+) span experimental kidney disease, clinical trials, and pre-clinical studies. Key areas include cellular senescence, PAR2 signaling, podocyte biology, and anti-fibrotic drug discovery. He currently supervises 4 PhD students and maintains active collaborations through Monash Health and international networks. Key Projects: ASK1 inhibitor trials, kidney organoid modeling, biomarker development Grants/Support: Multiple ARC and NHMRC grants since 2016 Labs/Teams: Head of Research Lab at Monash Health, collaborating with Polo (STEM cell), Combes (fibrosis), and Tesch (clinical trials)

Isabel Orrissمشاهده پروفایل

مدرس ارشد

• Bone Cell Biology
• Vascular Calcification
• Purinergic Signaling
• +۴ مورد دیگر

Dr. Isabel Orriss is a Senior Lecturer in the Department of Comparative Biomedical Sciences at the Royal Veterinary College (RVC), where she has worked since 2013. Her research focuses on bone cell regulation and vascular calcification through local signaling factors like extracellular nucleotides and purinergic pathways. University of Southampton, Biochemistry BSc (1st Class, 2001) University College London, PhD (2005, supervised by Professors Tim Arnett and Geoff Burnstock) Her research examines how extracellular nucleotides , antioxidants , and pH levels influence skeletal mineralization and soft tissue calcification. She has published over 40 peer-reviewed articles and leads the Bone Biology, Biomineralisation and Purinergic Signalling research group within Skeletal Biology at RVC. Recent studies highlight her work on: Mechanisms of NPP1 regulation by acidosis ATP-mediated inhibition of bone mineralization Effects of purinergic receptor antagonists Interactions between metabolic hormones and bone She holds a Career Development Fellowship from Arthritis Research UK (2010) and serves on the editorial board of Frontiers in Endocrinology: Bone Research . Dr. Orriss teaches across the BVetMed and BSc Bioveterinary Science programs, leading modules like Cell Cycle and Advanced Skeletal Pathobiology .