Natalia DeMarco is an Associate Professor of Neuroscience at the Feil Family Brain & Mind Research Institute, Weill Cornell Medical College. Her lab investigates how genetic programs and neuronal activity interact during early brain development, focusing on inhibitory interneurons and their role in neurological disorders like autism, schizophrenia, and epilepsy. PhD, Columbia University (2007) Postdoctoral Fellowship, Patterson Trust (2009) DeMarco’s research explores mechanisms behind excitatory/inhibitory imbalance in the brain, using mouse models to study: Neurotransmitter roles (glutamate, GABA) in interneuron maturation Electrophysiology and viral tracing for circuit analysis Developmental origins of cortical connectivity Implications for autism, schizophrenia, and epilepsy Her 15 most recent publications (2023–2002) highlight trends in cortical circuit assembly, GABA signaling, and interneuron dysfunction. Keywords span neuroscience, genetics, and neurodevelopmental disorders, with subfields like synaptic connectivity, mouse genetics, and activity-dependent plasticity. Scientific awards include: K99/R00 Pathway to Independence Award (2012) Leon Levy Fellowship (2016) Irma Hirschl Career Scientist Award (2020) 2023 Paper of the Year (Babij, Ferrer et al.) DeMarco mentors MD/PhD students (e.g., Andrew Iannone, Rachel Babij) and collaborates with institutions like NYU, Stony Brook, and INSERM. Her lab, located in Manhattan, utilizes techniques such as optogenetics and in vivo imaging to study cortical development. Grants include R01 funding from NIMH and NINDS.






