جستجوی استاد راهنمای دانشگاهی

Prof. Dr. Katrien De Bock is a Full Professor and Deputy Head of the Department of Health Sciences and Technology at ETH Zurich. Her research focuses on angiogenesis, metabolic crosstalk in muscle microenvironments, and the impact of exercise on muscle regeneration. She leads a team investigating cellular interactions in skeletal muscle, particularly how metabolic signals regulate blood vessel growth and muscle repair. Key areas include understanding fibroadipogenic progenitors' role in muscle physiology, the role of histamine in exercise responses, and age-related muscle decline. Her work integrates molecular biology, single-cell transcriptomics, and computational approaches to dissect mechanisms underlying tendon pathologies, ischemic muscle injury, and metabolic adaptations to exercise. She supervises Master's programs in Human Movement Science and collaborates on projects involving muscle stem cell therapies and vascular engineering. Prof. De Bock also explores interventions like NAD+ precursors to counteract age-related sarcopenia and promotes translational research in regenerative medicine. Research Interests: Exercise-induced metabolic pathways in muscle repair Angiogenesis regulation in health and disease Hypoxia signaling in tendons and muscles Epigenetic modifications during tissue regeneration Stem cell fate determination in muscle microenvironments Notable Projects: Developing AI-driven histologic analysis for tendinopathy diagnosis Mapping the human brain vasculature at single-cell resolution Testing sulfur amino acid restriction to enhance exercise capacity

• Muscle Microenvironment
• Angiogenesis
• Metabolic Crosstalk
• +۴ مورد دیگر

George Coukos is a full professor at the University of Lausanne (UNIL), affiliated with the Faculty of Biology and Medicine, and serves as Director of the Department of Oncology at UNIL-CHUV. He also leads the Ludwig Institute for Cancer Research Lausanne and is set to direct the future Swiss Cancer Center Lausanne. He joined Lausanne in July 2012 after founding the Ovarian Cancer Research Center at the University of Pennsylvania in Philadelphia. His research focuses on cancer immunotherapy , particularly in gynecological cancers such as ovarian cancer. Key areas include understanding the tumor microenvironment , especially the vascular network, engineering chimeric antigen receptor (CAR) lymphocytes , and developing experimental mouse models of cancer. His work leverages high-throughput sequencing and molecular profiling to advance precision oncology , integrating patient genetics with clinical data for personalized treatment. The recent publications and news items highlight a strong trend toward T cell immunity , adoptive cell therapy , and overcoming immunosuppressive mechanisms in the tumor microenvironment, such as PGE2-mediated inhibition of TIL expansion. His contributions are central to advancing clinical trials in Switzerland and Europe. Leenaards Prize for Scientific Research ERC Advanced Grant 2021 ESMO Prize Election to the National Academy of Medicine (2024) Doctor Honoris Causa from NKUA (2025) George Coukos leads a broad cancer research program spanning fundamental biology to clinical research, including preclinical and phase I clinical protocols. He has secured nearly 5 million francs in research funding and is instrumental in uniting oncology research and practice in the Lake Geneva region. He mentors researchers and leads collaborative teams at UNIL-CHUV and the Ludwig Institute. His vision includes developing the Swiss Cancer Center Lausanne as a pan-institutional hub for innovation in cancer care. He directs major research initiatives including the Swiss Cancer Center Lausanne and is a key figure in the UNIL-CHUV Department of Oncology and the Ludwig Institute for Cancer Research Lausanne. His leadership fosters strong collaboration between research centers and clinical oncology practice, aiming to improve patient outcomes through networked, data-driven approaches.

• Cancer Immunotherapy
• Gynecological Cancers
• Tumor Microenvironment
• +۷ مورد دیگر

Markus Stoffel is a Full Professor at the Department of Biology, ETH Zurich, Switzerland. His laboratory is located at Otto-Stern-Weg 7, 8093 Zürich. As a leading researcher in metabolic diseases, Prof. Stoffel investigates the fundamental molecular mechanisms that regulate glucose and lipid metabolism through transcriptional and translational regulators controlling energy homeostasis in pancreatic β-cells, liver, fat, and hypothalamus. Prof. Stoffel's research program spans multiple interconnected domains of metabolism and gene regulation. His laboratory investigates insulin signaling pathways across metabolic tissues, with particular focus on the transcription factor Foxa2 and its role in lipid metabolism and ketogenesis. His team studies the MODY transcription factor network (Hnf-1α, Foxa1, Hnf-4α and Pdx-1) and its critical function in pancreatic β-cell biology. Additional research streams include pancreatic islet growth and regeneration mechanisms, microRNA regulatory networks in metabolic tissues, HDL metabolism and reverse cholesterol transport, and population genetics of type 2 diabetes in founder populations. Analysis of Prof. Stoffel's publication record from 2021-2023 reveals a sophisticated integration of molecular biology, systems approaches, and translational research. His recent work demonstrates significant contributions to understanding pancreatic β-cell function in diabetes, molecular mechanisms of pancreatic cancer, microRNA regulation in metabolic homeostasis, and novel imaging techniques for metabolic processes. A unifying theme across his publications is the investigation of transcriptional and post-transcriptional regulatory networks that maintain metabolic balance and their dysregulation in disease states. Prof. Stoffel actively recruits and mentors the next generation of scientists, currently seeking both postdoctoral fellows directly through his laboratory and PhD students through the Systems Physiology and Metabolic Diseases (CC-SPMD) program at ETH Zurich. His research group maintains extensive collaborations with other groups at ETH Zurich including the Aceto, Bodenmiller, Corn, Gehart, Kopf, Suter, Werner, Wutz, and Zindel groups, reflecting the interdisciplinary nature of modern metabolic research.

• Metabolism & Metabolic Diseases
• Glucose and Lipid Metabolism
• Transcriptional Regulation
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Lubor Borsig is a Professor at the University of Zurich, leading the Cell Physiology and Glycobiology research group. His work focuses on cancer progression, metastasis, and the role of glycosylation in tumor-microenvironment interactions. Research Focus: Cancer-associated glycosylation, tumor microenvironment signaling, gut microbiota effects on colorectal cancer Methodologies: Cancer mouse models, glycan analysis, CRISPR/Cas9 gene editing, flow cytometry, confocal microscopy His recent publications (2018-2025) explore glycan-lectin interactions, chemokine signaling in metastasis, microbiome-mediated immunotherapy, and transcription factor regulation in tumor development. Current team includes PhD candidates Anna La Torraca, Carla Stornante, and Elisa Poncioni, along with visiting student Alzbeta Minarcikova.

• Cancer progression
• Metastasis
• Cell-surface glycosylation
• +۳ مورد دیگر

Jun Abe is a Senior Researcher at the University of Fribourg's Faculty of Science and Medicine, affiliated with the Section of Endocrinology, Metabolism and Cardiovascular System (EMC). His work focuses on immunology, particularly mechanisms of T cell migration, tumor immunology, and lymph node microenvironment dynamics. Key Research Themes: T cell mechanosensing, high endothelial venule biology, tumor rejection, and metastasis. Publications: Over 35 articles spanning cancer immunology, mucosal immunity, and inflammatory disease mechanisms. His recent studies employ advanced imaging techniques to dissect immune cell interactions in lymphoid and tumor tissues, revealing critical pathways for therapeutic intervention.

• Immunology
• Cancer Immunotherapy
• T Cell Biology
• +۵ مورد دیگر

Karin Ribi is a Senior Researcher at the Careum School of Health, affiliated with Kalaidos University of Applied Sciences. Her work spans clinical cancer research, focusing on patient-reported outcomes, psycho-oncology, geriatric oncology, and resilience. Previously, she held roles at the University Institute for Teaching and Research in Health Services Sciences, University of Lausanne, and University Hospital Lausanne. Doctorate in Psychology Master of Advanced Studies in Public Health (Universities of Zurich, Bern, Basel) Her research explores digital health literacy, self-management in cancer survivors, financial burdens of chronic illness, and peer-led care models. Current projects include GiveCare (gender-sensitive end-of-life care), INSIDE (health literacy), and FINK (financial burden in chronic illness). Recent publications highlight trends in immunotherapy for NSCLC, lymphedema treatment, and self-management frameworks. Despite no explicit awards listed, her leadership in multi-institutional trials underscores her impact in oncology and nursing research. She has led oral presentations on topics like Digital Health Literacy and Young Carers in Palliative Care and contributes to public discourse via platforms like the blog «Personenzentrierte Versorgung liegt mir am Herzen» .

• Patient-Reported Outcomes
• Quality of Life
• Psycho-Oncology
• +۵ مورد دیگر

Prof. Dr. med. Michael Leunig is a Chief Physician of Hip Surgery and Chief Medical Officer at Schulthess Klinik in Zurich, Switzerland. He also holds an Associate Professorship at ETH Zürich since 2018. Specializes in joint-preserving hip surgery for deformities like femoroacetabular impingement, hip dysplasia, and post-traumatic conditions Expertise in hip arthroscopy, osteotomies, and hip replacement for osteoarthritis Research Focus: Hip surgery, femoroacetabular impingement, osteoarthritis, bone graft cryopreservation, and surgical outcomes. His work is supported by continuous funding from the Swiss National Science Foundation (SNF) since 1995. Scientific Contributions: Over 15 recent publications analyze hip pathology, surgical techniques, and patient-reported outcomes. Key trends include diagnostic criteria for hip pain, non-surgical treatment rationales, and international consensus-building. Awards: 2018 JBJS Essential Methods Best Paper Award, 2010 John Charnley Trust Medal, 2001 SOPUR-Preis Grants: Received significant funding from Mäxi Foundation, SNF, SYNOS Foundation, and Deutsche Arthrose-Hilfe

• Hip Surgery
• Femoroacetabular Impingement
• Osteoarthritis
• +۳ مورد دیگر

Philipp Berger is a Scientist at the Paul Scherrer Institute (PSI) in Switzerland, affiliated with the Center for Life Sciences and leading the Laboratory for Multiscale Bioimaging . His position as a research group head involves developing advanced tools for cellular engineering and microscopy while investigating receptor signaling mechanisms in biomedical contexts. Research focuses on receptor trafficking and signaling pathways , particularly VEGFR-2 and GPCRs. Berger's group demonstrated how VEGF-A isoforms alter coreceptor recruitment and signaling (Ballmer-Hofer et al., 2011), identified TBC1D10 as a VEGFR2 signaling regulator (Xie et al., 2019), and pioneered split nanoluciferase assays to study time-resolved adapter protein recruitment for GPCRs (Romantini et al., 2021). Core expertise spans molecular engineering of cellular processes and quantitative microscopy. Recent publications (2021-2023) reveal diversification into diagnostic applications (polymer brush diagnostics, SARS-CoV-2 nanofluidic devices) and neurodegenerative disease mechanisms (Apolipoprotein E-amyloid interactions), while maintaining foundational work on receptor trafficking. The lab's signature tools—Squassh for image analysis and baculovirus systems for multigene delivery—underpin most studies. Scientific Awards: No awards mentioned in source materials Advising and Grants: Berger leads a research group with active publications indicating supervision of junior scientists, though specific students aren't listed. Extensive tool development and cross-disciplinary collaborations (e.g., nuclear medicine, virology) imply sustained grant funding, though specific grants aren't documented in the provided text. Labs and Teams: He directs the Laboratory for Multiscale Bioimaging at PSI. His team developed the MultiLabel/MultiPrime cre/LoxP-based multigene expression system (Kriz et al., 2010; Mansouri et al., 2016), Squassh image segmentation tools (Rizk et al., 2014, 2015), and split nanoluciferase GPCR assays (Spillmann et al., 2020; Romantini et al., 2021). All tools are publicly available via download packages with manuals.

• Cellular Engineering
• Bioimaging
• Receptor Signaling
• +۴ مورد دیگر

Liliane Michalik is an Associate Professor at the University of Lausanne (UNIL), affiliated with the Center for Integrative Genomics within the Faculty of Biology and Medicine. She holds leadership roles, serving as Vice-Director (2011–2019) and Director (2019–2021) of the School of Biology and currently as Vice-Rector overseeing the "Equality, Diversity and Careers" department. Her academic journey includes a PhD from the University Louis Pasteur in Strasbourg (1993), followed by postdoctoral training and research at UNIL, culminating in her promotion to Associate Professor in 2018. Her research focuses on understanding cellular responses to environmental cues, particularly skin repair, UV-induced skin cancer, and angiogenesis, leveraging nuclear hormone receptors like PPARs. Her work integrates genomic approaches and mouse models to explore transcriptional regulation and disease mechanisms. Notable collaborations include studies on PPARβ/δ's role in UV-induced inflammation and Src activation in skin cancer. Michalik’s funding includes support from the Swiss National Science Foundation and the Swiss Foundation for Excellence and Talent in Biomedical Research. Her contributions extend to policy, as seen in her 2024 publication on strategies to promote gender equality in academia. She oversees a research group and has contributed to over 30 peer-reviewed articles, emphasizing interdisciplinary approaches in biology, pharmacology, and translational medicine. Her administrative leadership and scientific expertise position her as a pivotal figure in advancing both academic research and institutional equity initiatives.

• Skin Biology
• Cancer Biology
• Molecular Biology
• +۳ مورد دیگر

Professor Luis Filgueira is a Full Professor in the Department of Medicine at the University of Fribourg, affiliated with the Faculty of Mathematics, Natural Sciences and Medicine. He serves as Head of the Gross Anatomy domain and teaches gross anatomy, histology, embryology, cell biology, and immunology. His research focuses on clinical anatomy, medical education, cell biology, immunology, and stem cells, particularly in malaria and viral infection mechanisms. Key research interests include microglia-mediated neuroinflammation, extracellular vesicle biology in malaria, and anatomical innovations in medical education. His work bridges clinical anatomy with advanced microscopy techniques and pedagogical strategies. Recent publications emphasize viral neuropathology (Japanese encephalitis), metabolic gasotransmitters, and anatomical advancements in orthopedic surgery. His educational contributions include integrating ultrasound and peer-teaching methods to enhance musculoskeletal learning. Professor Filgueira coordinates the Certificate of Advanced Studies in Clinical Anatomy and collaborates with initiatives like the Toxin Academy. His work spans anatomical dissection techniques, cadaveric studies, and translational research in regenerative medicine.

• Clinical Anatomy
• Immunology
• Cell Biology
• +۳ مورد دیگر

Christian Stockmann is an Associate Professor at the Institute of Anatomy, Faculty of Medicine, University of Zurich. His research focuses on hypoxia-driven immune modulation , angiogenesis , and tissue remodeling in fibrosis and cancer. Hypoxia-inducible factors (HIFs) in immune cells Therapeutic vaccination against fibrotic diseases Immune-vascular crosstalk in pathology His research connects chronic tissue repair processes to cancer progression and organ fibrosis , investigating how immune cell metabolism under hypoxia influences disease outcomes. Recent projects funded by the Swiss National Science Foundation explore NK cell biology and metabolic immunotherapy . Notable collaborations include teams at ETH Zurich, VIB Leuven, and the Paris Cardiovascular Research Center. He received the Travel award from Molecular Life Sciences (UZH, 2022).

• Immunology
• Pathophysiology
• Cancer Research
• +۴ مورد دیگر

Alexey Larionov is a Senior Researcher at the Faculty of Science and Medicine, University of Fribourg, Switzerland. His primary affiliation is within the Medicine Section, where he focuses on advanced biomedical research. His work spans cardiovascular medicine, cellular biology, and infectious diseases, with a particular emphasis on endothelial dysfunction, microglia activity, and renal physiology. Larionov’s research integrates experimental and clinical approaches to address mechanisms underlying diseases such as diabetic kidney disease, SARS-CoV-2 neuropathology, and vascular pathologies. He holds a prominent role in anatomical and medical education, having contributed to innovative teaching methods during the pandemic. His expertise includes anatomical variations impacting clinical conditions like piriformis syndrome and the neuroinflammatory effects of viral infections. Larionov’s studies also explore therapeutic targets for cardiovascular and renal disorders, leveraging molecular mechanisms such as mTOR signaling and cathepsin enzyme activity. Though no formal academic awards are listed, his prolific publication record reflects sustained contributions to medical science. He is reachable at alexey.larionov@unifr.ch and maintains an ORCID profile (0000-0001-6902-8878).

• Cardiovascular Medicine
• Neuroscience
• Medical Research
• +۳ مورد دیگر

PD Dr. Vivianne Irene Otto is a Senior Lecturer (60% part-time) and Senior Scientist at the Institute of Pharmaceutical Sciences, ETH Zurich, within the Department of Chemistry and Applied Biosciences. She also holds a lectureship in the MSc course 'Glycosylation' at the University of Zurich. Her research focuses on endothelial cell glycobiology, particularly the roles of glycans in cell-cell interactions and their implications in drug development. Otto has held diverse academic roles including federal pharmacy exam coordination and editorial work in scientific communication. Education: PhD in Pharmaceutical Chemistry (1997, ETH Zurich) Habilitation in Pharmaceutical Biochemistry (2006, ETH Zurich) Advanced Studies in Science Journalism (2008-2009, maz School) Research Interests: Investigating endothelial cell glycomes, glycan roles in vascular biology, and translational applications in drug development. Current work emphasizes sialic acid's functional roles in lymphatic endothelial interactions and tumor vascular biology. Publications: Her work spans glycobiology fundamentals to translational cancer research, with recent focus on tumor vascular markers and lymphatic signaling mechanisms. Over 30 peer-reviewed articles highlight her expertise in glycoprotein structure-function relationships and vascular biomarkers. Teaching & Academic Service: Course leader for 'Glycobiology in Drug Development' and 'Pathobiology' Member of curriculum revision committees for MSc Pharmacy programs Editorial contributions to scientific communication initiatives Labs/Teams: Affiliated with the Institute of Pharmaceutical Sciences' glycobiology research group and collaborates with oncology teams studying tumor vasculature.

• Glycobiology
• Drug Development
• Endothelial Cell Biology
• +۳ مورد دیگر

Francesco Paneni is a Professor and Group Leader in Cardiovascular Epigenetics at the Department of Cardiology , with a focus on understanding how environmental factors interact with epigenetic mechanisms to drive cardiovascular disease. His research spans heart failure with preserved ejection fraction (HFpEF), diabetes-related CVD, aging, and metabolic disorders. Academic Rank: Professor Department: Department of Cardiology Key Research Areas: Cardiovascular Epigenetics, HFpEF, Diabetes and CVD, Aging in Cardiovascular Pathology His group investigates chromatin remodeling, BET protein inhibition, and epigenetic inheritance in cardiometabolic diseases. Recent publications highlight novel therapeutic strategies targeting SETD7 , BRD4 , and SIRT1 to reverse pathological pathways. Ongoing projects include identifying epigenetic biomarkers and developing interventions for perivascular adipose tissue dysfunction. His research aligns with translational approaches, bridging laboratory findings to clinical applications. Funding sources include the Swiss National Science Foundation and EU Framework Programme. His team comprises postdocs, PhD students, and research assistants working on epigenetic mechanisms in cardiovascular health.

• Cardiovascular Epigenetics
• Heart Failure with Preserved Ejection Fraction (HFpEF)
• Diabetes and Cardiovascular Disease
• +۳ مورد دیگر

Thomas Alexander MCKEE is an Associate Professor in the Department of Pathology and Immunology at the University of Geneva's Faculty of Medicine. His research focuses on multi-parametric analysis of colorectal and lymphoid tumors, with particular emphasis on genomic evolution in disease progression and metastasis development. Dr. MCKEE leads a research group that investigates genomic, transcriptomic and epigenomic changes in primary and metastatic colorectal cancers. His work examines how primary tumor profiling can define biological processes in matched metastases and assesses the importance of intratumoral heterogeneity. His research spans cancer genomics, molecular pathology, tumor microenvironment, and precision oncology approaches. Analysis of his recent publications (2021-2025) reveals a broad research portfolio covering colorectal cancer, lymphoid malignancies, ovarian cancer, and breast cancer. His work frequently bridges basic science with clinical applications, particularly in developing biomarkers for treatment response prediction and investigating mechanisms of drug resistance. A significant portion of his research involves translational approaches connecting genomic findings with therapeutic implications. His scientific contributions demonstrate expertise in cancer genomics, tumor evolution, and molecular pathology with applications across multiple cancer types. His work often involves collaborative research with clinical teams to translate genomic findings into potential clinical applications. Dr. MCKEE maintains an active research program with numerous publications in high-impact journals including Science, JCO Precision Oncology, and Frontiers in Immunology, reflecting his contributions to both basic cancer biology and clinical oncology research.

• Cancer genomics
• Colorectal cancer
• Lymphoid tumors
• +۵ مورد دیگر