معرفی
Thomas Alexander MCKEE is an Associate Professor in the Department of Pathology and Immunology at the University of Geneva's Faculty of Medicine. His research focuses on multi-parametric analysis of colorectal and lymphoid tumors, with particular emphasis on genomic evolution in disease progression and metastasis development.
Dr. MCKEE leads a research group that investigates genomic, transcriptomic and epigenomic changes in primary and metastatic colorectal cancers. His work examines how primary tumor profiling can define biological processes in matched metastases and assesses the importance of intratumoral heterogeneity. His research spans cancer genomics, molecular pathology, tumor microenvironment, and precision oncology approaches.
Analysis of his recent publications (2021-2025) reveals a broad research portfolio covering colorectal cancer, lymphoid malignancies, ovarian cancer, and breast cancer. His work frequently bridges basic science with clinical applications, particularly in developing biomarkers for treatment response prediction and investigating mechanisms of drug resistance. A significant portion of his research involves translational approaches connecting genomic findings with therapeutic implications.
His scientific contributions demonstrate expertise in cancer genomics, tumor evolution, and molecular pathology with applications across multiple cancer types. His work often involves collaborative research with clinical teams to translate genomic findings into potential clinical applications.
Dr. MCKEE maintains an active research program with numerous publications in high-impact journals including Science, JCO Precision Oncology, and Frontiers in Immunology, reflecting his contributions to both basic cancer biology and clinical oncology research.
