Advanced Fluorescence Microscopy Professors and Supervisors | ApplySharif

جست‌وجوی استاد و پژوهشگر

استاد راهنما، استاد دانشگاه یا پژوهشگر مناسب برای مسیر پژوهشی‌تان را پیدا کنید و با او ارتباط بگیرید.

نمایش ۷۳۶-۷۵۰ از ۱٬۹۰۵ استاد راهنما

اطلاعات این پروفایل‌ها از صفحات عمومی دانشگاه‌ها جمع‌آوری شده و ممکن است به‌روز نباشد.

Laura Macheskyمشاهده پروفایل

استاد

University of GlasgowUnited Kingdom

Professor Laura Machesky is an Affiliate at the School of Cancer Sciences, University of Glasgow. With a distinguished career spanning several decades, she has made significant contributions to our understanding of cell migration, cancer metastasis, and actin cytoskeleton dynamics. Her research has been widely published in high-impact journals, focusing on how cellular mechanics and signaling pathways contribute to cancer progression. Professor Machesky's primary research interests center around the actin cytoskeleton and its role in cell migration and cancer metastasis. Her work particularly investigates how proteins like CYRI, Rac1, and the WAVE regulatory complex control cell movement and invasion. She has made significant contributions to understanding how pancreatic cancer cells migrate and metastasize, with a focus on macropinocytosis, integrin regulation, and mechanical properties of the tumor microenvironment. Her research combines molecular, cellular, and in vivo approaches to unravel the complex mechanisms driving cancer progression. Analysis of Professor Machesky's recent publications reveals a consistent focus on the molecular mechanisms of cancer cell migration and metastasis. Her work prominently features studies on CYRI proteins and their role in regulating actin dynamics during the "eat vs walk" decision in cells. There's also a strong emphasis on pancreatic cancer research, melanoma, and the development of advanced imaging techniques to study cellular processes. Her research bridges basic cell biology with clinically relevant cancer mechanisms, providing insights that could inform future therapeutic strategies. While specific grant details aren't provided in the available information, Professor Machesky's extensive publication record suggests sustained research funding supporting her investigations into cell migration and cancer metastasis mechanisms. Her work has fostered numerous collaborations across disciplines, integrating cell biology, cancer research, and advanced imaging techniques. Her laboratory appears to focus on the intersection of cell biology and cancer research, with particular emphasis on the actin cytoskeleton's role in cancer cell migration. The research team likely combines molecular biology, live-cell imaging, and animal models to investigate how cancer cells invade and metastasize, with special attention to pancreatic cancer and melanoma models.

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Richard Meekمشاهده پروفایل

پژوهشگر ارشد

University of SouthamptonUnited Kingdom

Dr. Richard Meek is a Senior Research Fellow at the University of Southampton, specializing in eukaryotic glycobiology and carbohydrate-processing enzymes. His work intersects structural enzymology with neurodegenerative disease research, focusing on post-translational modifications and cell signaling networks. Key affiliations include the Plants and Food Security group, Neuroscience Institute for Life Sciences , and the ChemLife Network . His research addresses the roles of glycosylation defects in diseases like Primary Familial Brain Calcification. Glycosylation and neurodegeneration : Investigates how defective carbohydrate-processing enzymes drive neurodegenerative disorders. Fundamental glycobiology : Explores enzyme mechanisms through chemical tools and structural analysis. Recent publications highlight advancements in O-GlcNAc transferase inhibition, cryo-EM enzyme structures, and macrocyclic peptide therapeutics. He supervises PhD students Jacob Willcox (SoCoBio) and Nicole Elise James (Biological Sciences), accepting applications for new advisees. Contact: R.W.Meek@soton.ac.uk

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Erik Snappمشاهده پروفایل

استاد مدعو

Johns Hopkins UniversityUnited States

Erik Snapp is an Adjunct Professor of Neuroscience and Director of Student and Postdoctoral Programs at the Howard Hughes Medical Institute's Janelia Research Campus. His research focuses on the cell biology of secretory protein synthesis, leveraging live cell imaging, fluorescence microscopy, and biochemical techniques to study endoplasmic reticulum (ER) dynamics and protein folding mechanisms. He directs programs fostering collaborative neuroscience research with an emphasis on computational approaches and tool development, particularly in fluorescent protein technologies. Snapp's work addresses protein misfolding diseases (e.g., cystic fibrosis) and viral exploitation of ER processes (e.g., HIV). He has pioneered methods like FRAP and FLIP for protein mobility studies and developed advanced fluorescent probes for oxidizing cellular environments. His recent efforts include optimizing fluorescent proteins for organelle-specific use and writing a free eBook on securing faculty positions. He leads the Janelia Joint Graduate Program in Neuroscience, collaborating with Johns Hopkins University. His research integrates quantitative microscopy, molecular biology, and biochemistry to dissect ER function under stress conditions and during disease states.

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Xantha Karpمشاهده پروفایل

استاد

Central Michigan UniversityUnited States

Dr. Xantha Karp is a Professor in the Department of Biology at Central Michigan University (CMU), where she has been a faculty member since 2012. She is affiliated with the College of Science and Engineering and leads the Karp Lab, which focuses on genetics, developmental biology, and cell biology using the model organism C. elegans . Her research is supported by the NIH and NSF, and she teaches foundational courses such as Genetics and Cell Biology. B.S. in Human Biology and Anthropology, University of Toronto, 1995 Ph.D. in Genetics and Development, Columbia University, 2004 Postdoctoral training at Dartmouth College and University of Massachusetts Medical School Dr. Karp's research centers on how developmental arrest (diapause or dauer) affects stem and progenitor cell fate, particularly how cells maintain their developmental potential during quiescence. Her lab investigates the role of microRNA pathways, heterochronic genes, and transcription factors like daf-16/FOXO and lin-41 in post-dauer development. She uses C. elegans due to its invariant lineage, transparency, and genetic tractability, enabling single-cell resolution of developmental processes. Analysis of her recent publications reveals a strong focus on gene regulation during developmental arrest and recovery. Key themes include the modulation of microRNA activity, the role of conserved kinases in enhancing microRNA function, and the function of daf-16 isoforms in cell fate decisions. Her work bridges fundamental developmental biology with implications for stem cell quiescence and human health. Dr. Karp has received research funding from the National Institutes of Health (NIH) and the National Science Foundation (NSF) , supporting projects on diapause and developmental pathway modulation. While no specific scientific awards are listed, her sustained external funding and high-impact publications reflect significant recognition in her field. She actively mentors a diverse team of graduate and undergraduate students in the Karp Lab, advising PhD students in the BCMB program and MS students in BCMB or Biology. She also serves as an academic advisor for Biology majors, particularly those interested in genetics, cell biology, or medical school. Many of her former students have pursued advanced degrees, medical school, or research careers. The Karp Lab is a dynamic research environment that emphasizes inclusivity and hands-on learning. Undergraduate students participate in genetic and molecular experiments, data analysis, and co-author peer-reviewed publications. The lab is equipped in Biosciences 3200 at CMU and fosters a collaborative, equity-focused culture.

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Alan F. Strautmanمشاهده پروفایل

عضو هیئت علمی

Miami UniversityUnited States

Alan F. Strautman is an Associate Teaching Professor in the Department of Microbiology at Miami University, within the College of Arts and Science. He is dedicated to undergraduate education, teaching foundational courses such as MBI 111, MBI 123, and MBI 131 for non-majors, and serves as a summer orientation advisor for Microbiology, Public Health, and pre-health students. He also advises the Microbiology Club, contributing to student engagement and academic support. Education: Ph.D. in Biological Sciences, Purdue University (1989) B.S. in Zoology, Miami University (1983) His research and teaching interests span Public Health , the Human Microbiome and Disease , and College Biology Education . With a strong background in cellular physiology, his earlier research focused on intracellular ionic dynamics, particularly calcium and pH changes in neurons and fertilized eggs. His recent focus has shifted toward understanding how microbial communities influence human health and disease, informed by his long-standing instruction in Anatomy and Physiology for pre-health students. The available publications, spanning from 1989 to 2001, reflect a trajectory from fundamental cell signaling and neurobiology to educational innovation. They demonstrate expertise in calcium imaging , excitotoxicity , fertilization physiology , and the integration of technology in biology education . Collectively, the work bridges molecular cell biology and pedagogical advancement. Scientific Awards: No scientific awards listed in the provided text. As an instructional faculty member, Dr. Strautman does not accept graduate students and thus has no formal advisees. He has extensive experience in curriculum development, program administration, and multi-modal teaching (classroom, lab, online) across private, public, and for-profit institutions. His service includes advising and mentoring undergraduate students and clubs. While no grants are explicitly mentioned, his work in educational technology and cellular research suggests involvement in academic and possibly instructional innovation initiatives. He is actively engaged in the academic community through teaching, service, and scholarship, with a focus on enhancing undergraduate science education and promoting public understanding of microbiology and health.

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Simone Wiegandمشاهده پروفایل

پژوهشگر

Jülich Research CenterGermany

Prof. Dr. Simone Wiegand is a Senior Scientist at the Institute for Biological Information Processes (IBI) within the Biomacromolecular Systems and Processes (IBI-4) department at Forschungszentrum Jülich. Her research focuses on understanding transport processes in aqueous systems, particularly hydrogen bond dynamics and their role in biological and pharmaceutical reactions. She employs advanced optical and scattering methods to study thermodiffusion and thermophoresis under thermal gradients, with applications ranging from origin-of-life scenarios to drug delivery systems. Her expertise includes thermal diffusion forced Rayleigh scattering, light scattering techniques, and holographic grating optimization for quantitative studies. Key research interests involve the interplay between hydration layers and transport phenomena, with recent work emphasizing non-monotonic Soret coefficient behavior in salt solutions and the development of microfluidic devices for thermophoretic analysis. Publications highlight advancements in thermal diffusion mechanisms, colloidal particle behavior, and the role of thermophoresis in prebiotic chemistry. Her interdisciplinary approach bridges physics, chemistry, and biology, addressing fundamental questions about molecular interactions and their practical implications in healthcare and energy materials.

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Yunfeng Nieمشاهده پروفایل

پژوهشگر

Vrije Universiteit BrusselBelgium

Yunfeng Nie serves as a postdoctoral researcher at the Applied Physics and Photonics department within the Faculty of Engineering at Vrije Universiteit Brussel. His research integrates optical engineering with computational methods, focusing on advanced imaging systems development. His primary research interests include Optical design , Freeform optics , and Computational imaging , with significant contributions in Deep learning applications for microscopy and endoscopy. His work bridges theoretical optics with practical medical imaging solutions, particularly in aberration correction and resolution enhancement. Analysis of his recent publications reveals a strong trend toward deep learning-enhanced optical systems , with increasing focus on medical diagnostics applications. His 2025 publications demonstrate convergence of optical modeling, neural networks, and hyperspectral imaging for cancer diagnostics and microscopic resolution enhancement. Scientific awards: Michael Kidger Memorial Scholarship award (2016) Rising star award from Journal of Optics (2024) Nie actively supervises graduate research and leads significant projects. His current research includes two major funded projects: Computational Incoherent holographic single-shot plenoptic camera (2024-2027) and Super-sensitive fluorescence biochip detection (2021-2024), demonstrating sustained research funding and leadership in optical engineering. His work is conducted within Brussels Photonics (B-Phot), a leading photonics research group at VUB, where he contributes to both theoretical optical design and practical imaging system development.

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Marc Brechtمشاهده پروفایل

استاد

Reutlingen UniversityGermany

Prof. Marc Brecht is a faculty member at Reutlingen University, serving as Vice-Dean for Studies and Programme Director of the Bachelor Biomechatronics programme. He is affiliated with the School of Life Sciences and leads the Process Analysis & Technology research group. His academic focus lies in experimental physics and high-resolution spectroscopic methods, particularly applied to biomedical and materials science challenges. His research emphasizes advanced spectroscopic techniques like UV hyperspectral imaging, Raman spectroscopy, and SERS (Surface-Enhanced Raman Spectroscopy) for applications in cancer diagnostics, material characterization (e.g., copper substrates, cotton fibers), and drug delivery (e.g., hypericin studies). Recent work includes developing workflows for tumor tissue identification using Raman spectroscopy and improving quality control in industrial materials via hyperspectral analysis. Collaborations span multidisciplinary teams in physics, chemistry, and biomedical engineering. No scientific awards are explicitly mentioned, but his extensive publication record reflects active research engagement.

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Jakub Nedbalمشاهده پروفایل

پژوهشگر

King’s College LondonUnited Kingdom

Jakub Nedbal is a Researcher at King’s College London’s Department of Physics within the Faculty of Natural, Mathematical & Engineering Sciences. He holds a Master’s in Physics from Masaryk University (Czech Republic) and a Master’s in Immunology from King’s College London, alongside a PhD focused on imaging techniques in B cell biology. His research specializes in developing advanced fluorescence-based imaging technologies, particularly leveraging SPAD arrays and time-correlated single-photon counting (TCSPC) techniques. Notable contributions include creating the first fluorescence lifetime flow cytometer using TCSPC and co-developing a fast TCSPC microscope with parallelized SPAD array detectors. Current work focuses on spatially resolved TCSPC detectors for thick-sample imaging and low-phototoxicity techniques. Outside academia, Jakub served as Product Development Lead for a startup commercializing TCSPC array cameras until 2018. His innovations have been applied to art conservation via fluorescence lifetime imaging (FLIM) for varnish analysis and have advanced microalgae cultivation bioreactor designs. His research interests span fluorescence lifetime imaging, microscope development, SPAD arrays, and photosynthesis studies. Recent work highlights include a novel dual-excitation fluorometer for photosynthesis research and a SPAD array camera for lightsheet FLIM. His techniques address challenges in live-cell imaging phototoxicity and high-throughput FRET screening.

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Igor Stefaniniمشاهده پروفایل

پژوهشگر

University of Applied Sciences and Arts of Southern SwitzerlandSwitzerland

Igor Stefanini is a Senior Researcher and Head of the BIOMEDtech Unit at the Department of Innovative Technologies (DTI), SUPSI. He coordinates the Biomedical Technologies Research Line and oversees the Medical Technologies Teaching Module. He also serves as Research Coordinator at the Cardiocentro Ticino Foundation. His academic career includes a Doctorate from EPFL (2001-2006) and postdoctoral fellowship at EPFL (2006-2007). **Research Interests:** Development of precision systems in MEDtech and BIOtech fields, including biosensors for viral detection ( e.g. , SARS-CoV-2), energy harvesting for medical devices, and advanced biomedical instrumentation. Projects focus on microfluidic platforms, implantable sensors, and medical device prototyping. **Key Projects:** Includes a microfluidic platform for real-time SARS-CoV-2 detection , self-powering pacemakers , and CPR monitoring devices . Collaborations span institutions like the Institute of Oncology Research (IOR) and the Swiss Institute for Regenerative Medicine. **Patents:** Inventions include devices for adipose tissue globule production and CPR assistance systems. Over 30+ publications in journals like Biosensors and Bioelectronics: X and conference proceedings. **Grants & Roles:** Managed projects funded by CTI, Swiss Stem Cell Foundation, and industry partners. Served as Director of the Foundation for Cardiological Research and Education (2013–2015). **Labs/Teams:** Leads the Medical Devices (ADM) division at DTI, focusing on translational biomedical engineering and industry-academia partnerships.

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Abbas Kaziempourمشاهده پروفایل

مدرس

University of VirginiaUnited States

Abbas Kaziempour is a Lecturer at the School of Data Science, University of Virginia. He holds a Ph.D. in Electrical Engineering from the University of Maryland and a B.S. in Electrical Engineering from the University of Tehran. His research bridges deep learning, signal processing, and neuroscience, focusing on optimization, nonlinear dimensionality reduction, and biomedical imaging technologies. Ph.D., Electrical Engineering, University of Maryland B.S., Electrical Engineering, University of Tehran Kaziempour's work spans three key areas: (1) advancing deep learning theory through analysis of loss landscapes and optimization algorithms, (2) developing compressed sensing and polynomial PCA techniques for neuroscience and biomedical signal processing, and (3) engineering high-speed imaging systems like kilohertz frame-rate two-photon tomography. His recent publications highlight methodological innovations in machine learning and their applications to neural data analysis. As an applied scientist at Amazon's search relevance team, he translates theoretical insights into practical feature design and modeling solutions for industrial-scale problems. His academic contributions include (1) theoretical guarantees for sparse model recovery, (2) stability analysis of autoregressive estimation, and (3) novel approaches to signal deconvolution using state-space models.

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Richard A. Rachubinskiمشاهده پروفایل

استاد

University of AlbertaCanada

Richard A. Rachubinski is a Professor in the Department of Cell Biology at the University of Alberta, Faculty of Medicine & Dentistry. He conducts cutting-edge research on peroxisome biogenesis and related human genetic disorders, utilizing model systems including yeast and Drosophila. His laboratory is located in the Medical Sciences Building, where he leads a research team investigating the molecular mechanisms of organelle formation and inheritance. Dr. Rachubinski earned his Ph.D. from McGill University and has established himself as a leader in cell biology. His work bridges fundamental cellular processes with clinical implications for peroxisome biogenesis disorders (PBDs), which are severe and often lethal conditions in humans. His research focuses on the molecular cascade of peroxisome biogenesis, leveraging global approaches such as differential gene expression analysis, proteomics, fluorescence microscopy, and subcellular fractionation. He studies how peroxisomes form from the endoplasmic reticulum, how they divide and are inherited during cell division, and how their dysfunction leads to disease. His lab uses Yarrowia lipolytica , Saccharomyces cerevisiae , and Drosophila as model organisms, capitalizing on their genetic tractability and evolutionary conservation of peroxisomal mechanisms. The analysis of his recent publications reveals a strong focus on organelle dynamics, membrane contact sites, peroxin functions, and disease modeling. His work spans molecular mechanisms of protein import, organelle population control, lipid droplet inheritance, and immune-metabolic crosstalk, reflecting a multidisciplinary and systems-level approach to cell biology. Scientific Awards: Distinguished University Professor Howard Hughes Medical Institute International Research Scholar Canada Research Chair in Cell Biology Canadian Institutes of Health Research Senior Investigator Fellow of the Royal Society of Canada Fellow of the Canadian Academy of Health Sciences Fellow of the American Association for the Advancement of Science Dr. Rachubinski mentors research trainees including postdoctoral associates and technicians. He collaborates extensively, notably with Dr. Andrew Simmonds on Drosophila models of PBDs. His research is supported by major grants from national and international agencies, enabling high-impact studies with translational potential for rare genetic diseases. His lab continues to explore novel proteins and mechanisms in peroxisome biology, aiming to identify therapeutic strategies for peroxisome-related disorders. Laboratory and Team: His laboratory includes Research Associate Dr. Barbara Knoblach and Technician Hanna Kroliczak, forming a dedicated team advancing the understanding of peroxisomal and organelle biology.

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Brittany Carrمشاهده پروفایل

استادیار

University of AlbertaCanada

Brittany Carr is an Assistant Professor in the Department of Ophthalmology and Visual Sciences within the Faculty of Medicine and Dentistry at the University of Alberta. She holds a Ph.D. from the University of Calgary and leads a research laboratory focused on understanding the molecular and cellular mechanisms of inherited and age-related blindness, primarily using genetically modified Xenopus laevis (African clawed frog) as a model organism. Her lab is located in the Katz Building (7-030) and is actively engaged in cutting-edge research in retinal development and degeneration. Her primary research interests include: Inherited retinal degenerations and age-related macular degeneration (AMD) Metabolism of retinal waste products and identification of early disease biomarkers Photoreceptor outer segment morphogenesis and its role in disease The retinal circuitry involved in emmetropization and myopia (nearsightedness) Drug development for the therapeutic inhibition of myopia Dr. Carr employs a multidisciplinary approach in her research, with core methodologies spanning genetic modification (CRISPR-Cas9 and transgenesis), advanced imaging (confocal fluorescence microscopy, transmission electron microscopy, optical coherence tomography, and color fundus photography), and molecular biology (PCR, Western blotting, cloning). Her recent publications, including a 2024 journal cover feature in the Journal of Cell Science , demonstrate a consistent focus on gene function in retinal structure and disease, particularly the role of genes like prominin-1 in photoreceptor development and degeneration. Her work has significant implications for identifying novel therapeutic targets for blindness. Her scientific achievements have been recognized through competitive funding, including a BrightFocus Macular Degeneration Research grant. She is also an active member of the vision science community, participating in national and international conferences and engaging in science communication. Dr. Carr mentors the next generation of scientists, currently supervising graduate students Mahnoor Shoukat and Isaac Cantine, and a lab technician, Susanne Lingrell. Her lab is part of a larger research ecosystem at the University of Alberta dedicated to advancing knowledge in vision science and developing treatments for blinding diseases. She is also involved in educational initiatives, including contributing to the online textbook Webvision .

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Simon Connellمشاهده پروفایل

دانشیار

University of LeedsUnited Kingdom

Dr Simon Connell is an Associate Professor in the School of Physics at the University of Leeds, Faculty of Engineering and Physical Sciences. His research focuses on the development and application of Atomic Force Microscopy (AFM) and complementary techniques to study biological and soft matter systems at the nanoscale. Research Interests: His expertise lies in biological physics and nanomechanics, particularly in the study of lipid bilayers, fibrin clot formation, mechanical properties of soft materials, and pharmaceutical crystal surfaces. He investigates nanodomain structures such as lipid rafts, the biomechanics of fibrin networks, and the viscoelastic behavior of hydrogels and microgels. Techniques and Facilities: He manages the Leeds EPSRC AFM Facility and employs a range of advanced methods including high-speed AFM, correlative fluorescence microscopy, Quartz-Crystal Microbalance with Dissipation (QCM-D), magnetic tweezers, Langmuir trough, and differential scanning calorimetry (DSC). These are used in combination to provide comprehensive characterization of soft and biological materials. Industrial Collaborations: His work includes significant industrial partnerships with pharmaceutical companies such as Pfizer, AstraZeneca (AZ), 3M Drug Delivery, Neutek, and Interpharm, focusing on drug formulation, inhalable particle behavior, and crystal mechanics. Current Projects Include: Lipid bilayers: phase, asymmetry, and dynamics Fibrinogen and blood clotting mechanisms Nanomechanics of hydrogels, microgels, and plant cell walls Pharmaceutical crystal surface energy and inter-particulate forces Advising and Grants: While specific students are not listed, his leadership of major research projects and facility management indicate an active supervisory role. His access to EPSRC-funded infrastructure suggests involvement in competitively funded research grants, particularly through collaborations with industry and national research councils.

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Johannes Broichhagenمشاهده پروفایل

پژوهشگر

Leibniz-Institut für Molekulare PharmakologieGermany

Johannes Broichhagen is Head of the Broichhagen Group at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin, where he leads research in the Chemical Biology section. He earned his PhD in 2014 from LMU Munich and conducted postdoctoral research at EPFL and the Max Planck Institute for Medical Research before joining FMP in 2020 as a Junior Group Leader. Education: Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg PhD: Ludwig-Maximilians-Universität München (2014) Postdoctoral Training: EPFL, Max Planck Institute for Medical Research His research focuses on developing synthetic, custom-tailored fluorescent probes for high-resolution imaging in living cells. Key areas include compartmentalized protein labeling , endogenous protein visualization , and photocontrol of GPCRs using innovative chemical tools. The lab’s work enables super-resolution microscopy, protein tracking, and stoichiometry measurements, particularly for GPCRs such as GLP1R and metabotropic glutamate receptors. A major achievement is the development of LUXendins —fluorophore-fused peptidic antagonists for live imaging of GLP1R in cells and tissues. The group employs photopharmacology and protein engineering to achieve spatiotemporal precision in receptor control, with implications for understanding cell signaling and diabetes research. Although specific article titles are not listed in the provided text, the lab's publications reflect strong activity in chemical biology, probe design, and GPCR dynamics. Scientific Awards and Recognitions: Picoquant Young Investigator Award (2022) ORCHEM Award for Young Scientists (2022) EPFL Fellow (Marie Curie, H2020) Römer-Prize (2014) EMBO Short-Term Fellowship (2012) PhD Fellowship, German National Academic Foundation (2011–2014) Broichhagen advises a team of postdoctoral researchers and PhD students, contributing to training the next generation of chemical biologists. His lab collaborates across disciplines and institutions, supported by competitive fellowships and grants. The Broichhagen Group is based at the FMP campus in Berlin-Buch, utilizing advanced technologies in molecular imaging and spectroscopy.

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