معرفی
Jakub Nedbal is a Researcher at King’s College London’s Department of Physics within the Faculty of Natural, Mathematical & Engineering Sciences. He holds a Master’s in Physics from Masaryk University (Czech Republic) and a Master’s in Immunology from King’s College London, alongside a PhD focused on imaging techniques in B cell biology.
His research specializes in developing advanced fluorescence-based imaging technologies, particularly leveraging SPAD arrays and time-correlated single-photon counting (TCSPC) techniques. Notable contributions include creating the first fluorescence lifetime flow cytometer using TCSPC and co-developing a fast TCSPC microscope with parallelized SPAD array detectors. Current work focuses on spatially resolved TCSPC detectors for thick-sample imaging and low-phototoxicity techniques.
Outside academia, Jakub served as Product Development Lead for a startup commercializing TCSPC array cameras until 2018. His innovations have been applied to art conservation via fluorescence lifetime imaging (FLIM) for varnish analysis and have advanced microalgae cultivation bioreactor designs. His research interests span fluorescence lifetime imaging, microscope development, SPAD arrays, and photosynthesis studies.
Recent work highlights include a novel dual-excitation fluorometer for photosynthesis research and a SPAD array camera for lightsheet FLIM. His techniques address challenges in live-cell imaging phototoxicity and high-throughput FRET screening.
