معرفی
Zhijin Wu is a Professor of Biostatistics and Director of the Doctoral Program in Biostatistics at Brown University's School of Public Health. His research focuses on developing statistical methods for high-throughput genomic technologies, including RNA sequencing, DNA microarrays, and single-cell sequencing. Key areas include normalization techniques, differential expression analysis, and integrative genomic approaches for epigenetic studies and cancer research.
Research interests span bioinformatics, epigenomics, and computational biology. Dr. Wu's work addresses challenges in data interpretation from technologies like NanoString nCounter and scRNA-seq, with applications in toxicology, cancer biomarker identification, and aging studies. His methodologies are applied to diverse biological systems, including diatom transcriptomics and murine models of colorectal cancer.
Publications emphasize statistical innovations for genomic data, such as latent variable models and normalization frameworks. Collaborative projects include epigenetic variations in cancer, immune cell activation dynamics, and drug synergy studies with GSK-3 inhibitors. The Center for Biostatistics and Health Data Science, co-located with his department, supports these interdisciplinary efforts.
