معرفی
Dr. Yvonne Lin serves as Assistant Dean for Academic Affairs and Associate Professor within the Department of Pharmaceutics at the University of Washington School of Pharmacy. Her academic appointments span multiple units including the Obstetric-fetal Pharmacology Research Unit (OPRU) and Pharmaceutics Faculty. She maintains active research and teaching roles while providing academic leadership across the institution.
Dr. Lin's educational background includes a BA in Biophysics from the University of California at Berkeley and a PhD in Pharmaceutical Sciences from the University of Washington. She completed postdoctoral training at St. Jude Children's Research Hospital, establishing her foundation in pediatric pharmacology and drug metabolism.
Her research program focuses on pharmacokinetics and pharmacogenomics with particular emphasis on natural product-drug interactions and the regulation of drug metabolizing enzymes in vulnerable populations. Dr. Lin investigates enzyme regulation in children and pregnant women, exploring how developmental and physiological changes impact drug metabolism. Her work utilizes metabolomics approaches to discover endogenous biomarkers related to drug metabolism and transport, with significant contributions to understanding vitamin D pharmacokinetics and CYP enzyme function.
Analysis of her recent publications reveals consistent focus on developmental pharmacology, particularly in pediatric and pregnancy populations. Her work bridges basic mechanistic studies with clinical applications, often examining special populations that are historically underrepresented in pharmacological research. The research demonstrates strong methodological diversity including in vitro systems, clinical pharmacokinetic studies, biomarker development, and physiologically based pharmacokinetic modeling.
Dr. Lin actively teaches multiple courses including PHARBE 506, PHARBE 510, PCEUT 507, and PCEUT 537. She serves as a research mentor with her laboratory accepting students, though specific advisees are not listed in available materials. Her research has received support through institutional resources including the Mass Spectrometry Center and Bioanalysis and Pharmacokinetics Lab.
Her laboratory maintains focus on translational pharmacokinetic research with particular attention to vulnerable populations. Current work investigates drug metabolism in cystic fibrosis patients, vitamin D clearance mechanisms, and the impact of bariatric surgery on drug disposition. The research integrates pharmacogenomic, metabolomic, and clinical pharmacokinetic approaches to address critical gaps in therapeutic optimization for special populations.
