Youri Hoogstrate

Youri Hoogstrate is Assistant Professor in Neurology at Erasmus MC, Erasmus University Rotterdam. His research focuses on molecular mechanisms in brain tumors, particularly glioblastoma and astrocytoma, using genomic and transcriptomic approaches.

Research examines epigenetic alterations, tumor microenvironment interactions, and signaling pathways in neuro-oncology. Utilizes high-throughput sequencing, bioinformatics, and molecular pathology techniques to identify therapeutic targets.

Recent publications characterize tumor microenvironment changes, epigenetic reprogramming in IDH-mutant astrocytomas, and EGFR signaling networks. Articles demonstrate advanced applications of transcriptomic analysis in neuro-oncology.

Awards include 2023 Best Publication of the Year. Contributes to multi-center neuro-oncology collaborations and supervises graduate researchers in cancer genomics.

Leads projects integrating computational biology with wet-lab validation in glioblastoma. Collaborates internationally on brain tumor genomics initiatives.