Iris de Heer

Iris de Heer is a Researcher in the Department of Anesthesiology at Erasmus MC. Her doctoral thesis (2025) focused on electroencephalographic monitoring of hypnotic depth in pediatric patients. Her research spans pediatric anesthesia optimization, neuro-oncology, and epigenetic mechanisms in cancer. Key areas include anesthesia protocols for children, tumor immunology in IDH-mutant astrocytomas, and epigenetic reprogramming in malignancies.

Her work combines clinical trials (e.g., randomized controlled trials on sevoflurane administration) with basic science investigations into tumor biology. Notable contributions include studies on glial scar formation's role in T-cell confinement and epigenetic reactivation of embryonic genes in astrocytomas. She collaborates internationally on neuro-oncology projects and has published in high-impact journals like Nature Communications and Acta Neuropathologica.