معرفی
Yiyun Huang is a Professor of Radiology and Biomedical Imaging at Yale University’s School of Medicine, serving as Director of Radiochemistry and the PET Radiochemistry program. His research focuses on developing PET radioligands for CNS receptors and transporters, including dopamine, serotonin, glutamate, and acetylcholine systems. His work spans chemistry, pharmacology, and clinical translation, with applications in neurodegenerative diseases, addiction, and psychiatric disorders. Huang holds a PhD from the University of Akron (1993) and completed postdoctoral training at the University of Pittsburgh School of Medicine.
Key contributions include advancements in PET radioligand design, in vivo pharmacology studies in animals, and clinical trials evaluating synaptic density and neuroimmune markers. Notable awards include the 2017 Distinguished Investigator Award from the Academy for Radiology & Biomedical Imaging Research and the 1999 NARSAD Young Investigator Award. His research integrates interdisciplinary teams, collaborating with institutions on projects like imaging synaptic vesicle protein 2A (SV2A) and cortisol regulation in alcohol use disorder.
Current clinical trials involve investigating brain cortisol metabolism in obesity, neuroimmune markers in PTSD, and dopamine transporter availability in Parkinson’s disease. His lab is affiliated with the Yale PET Center, contributing to translational imaging solutions for neurological and psychiatric conditions.