معرفی
Krista Fowles is a Researcher affiliated with the PET Center at the Yale School of Medicine, Yale University. Her work focuses on advancing positron emission tomography (PET) imaging techniques and radiotracer development for neuroscience, pharmacology, and translational medicine. Key research areas include synaptic density assessment via SV2A imaging, receptor-specific PET probes (e.g., mGlu5, S1P1, serotonin transporters), and applications in neurological disorders such as PTSD, addiction, and neurodegeneration.
Her research employs nonhuman primate models and translational approaches to study drug mechanisms (e.g., ketamine), synaptic plasticity, and neuroinflammatory processes. Collaborations with experts like Richard Carson, Daniel Holden, and Irina Esterlis highlight her interdisciplinary work in radiology, pharmacology, and molecular biology.
Publications emphasize radiotracer synthesis, PET kinetic modeling, and preclinical-to-clinical translation, with a focus on neuropharmacological targets and biomarker development for conditions like spinal cord injury, cocaine addiction, and traumatic stress responses.
