معرفی
Yiran Meng is a Postdoctoral Researcher at the Nuffield Department of Clinical Laboratory Sciences, University of Oxford. Affiliated with the Nerlov Group and MRC Molecular Haematology Unit, Meng focuses on hematopoietic stem cell (HSC) lineage commitment regulation and its implications for regenerative medicine.
- Education: MSc and PhD in Molecular/Cell Biology from Imperial College London
Research interests center on hematopoietic stem cell biology, particularly how epigenetic programming influences lineage fate restriction. Meng investigates HSC heterogeneity and its impact on age-related hematopoietic imbalances, combining molecular tools (high-throughput sequencing) with functional approaches (in vivo transplantation) to analyze bulk and single-cell dynamics.
Recent publications highlight Meng's work on epigenetic mechanisms governing HSC fate (2023) and bone marrow microenvironment regulation of hematopoietic aging (2020). The research aims to identify molecular pathways for potential therapeutic reprogramming of HSCs.
Current affiliations include:
- MRC Weatherall Institute of Molecular Medicine
- Nerlov Group: Hematopoietic Stem Cell Genetics
- MRC Molecular Haematology Unit
No formal advising roles or specific grants mentioned in available information. Lab activities involve mouse model characterization and molecular analysis of hematopoietic processes.