معرفی
Xiaolei Wang is an Associate Professor of Pathology and Laboratory Medicine at Tulane University School of Medicine, affiliated with the Tulane National Primate Research Center (TNPRC). She holds a PhD in Mucosal Immunology from Kunming Institute of Zoology, Chinese Academy of Sciences (CAS), and completed postdoctoral training at Fudan University and TNPRC. Dr. Wang's research focuses on immune system development in early life and immunopathogenesis of infectious diseases in pediatric hosts, particularly HIV, Zika, and tuberculosis. She leads studies on compartmentalized immune maturation in infants and strategies to optimize treatments targeting mucosal sites. Currently recruiting postdoctoral, graduate, and undergraduate researchers.
She serves on the TNPRC Institutional Animal Care and Use Committee (IACUC) and as an academic editor for scientific journals. Her work bridges primate models and clinical applications, emphasizing neonatal vaccinology and pediatric infectious disease prevention. Key contributions include uncovering mechanisms of CD4+ T cell depletion in SIV/HIV infection and the role of intestinal immune dynamics in viral pathogenesis.
Notable publications address SIV/HIV immunopathology in neonatal macaques, B cell maturation defects in viral infections, and maternal antibody effects on vaccine responses. Her lab investigates T follicular helper cell depletion in AIDS progression and strategies to combat latent viral reservoirs.
