معرفی
Werner Kovacs is a senior scientist at the Aceto Lab, ETH Zurich. He holds a PhD in Biochemistry/Biotechnology from Vienna University of Technology and conducted postdoctoral research at San Diego State University under Prof. Skaidrite Krisans. His work focuses on peroxisome biology, hypoxia signaling, and their roles in metabolic disorders and cancer, particularly clear cell renal cell carcinoma (ccRCC).
- Education: PhD in Biochemistry/Biotechnology, Vienna University of Technology
- Former Affiliations: Prof. Wilhelm Krek's group (Senior Scientist/Oberassistent, 2007-2018), San Diego State University (Postdoctoral Fellow)
Research Interests: His work explores how HIF-2α mediates pexophagy, linking peroxisome dynamics to lipid metabolism reprogramming in cancer. He investigates peroxisome homeostasis, ER stress pathways, and their implications in cholesterogenesis and tumorigenesis. His studies also address autophagy receptors and their posttranslational modifications in organelle turnover.
Scientific Contributions: Werner has contributed to understanding peroxisome deficiency in Zellweger syndrome, cholesterol dysregulation in knockout models, and TGFβ-mediated organelle proliferation. He has taught courses in Molecular Cell Biology, Molecular Medicine, and Cancer Cell Signaling and managed animal research protocols as principal study director.
