Wendy Jean Mack

Wendy Jean Mack, PhD, is a Professor of Biostatistics in the Department of Preventive Medicine at the Keck School of Medicine of the University of Southern California (USC). She co-directs the Division of Biostatistics graduate programs and leads Biostatistics Resources at the Southern California Clinical and Translational Science Institute (SC CTSI). With over 20 years of experience, her expertise spans the design, conduct, and analysis of clinical trials and observational studies, particularly in the NIH-funded realm. She directs biostatistical activities for the USC Alzheimer’s Disease Research Center and other research programs. Mack received her doctorate from USC and has contributed to numerous NIH study sections, including the NHLBI Clinical Trials Review panel. Her research focuses on biostatistical methodologies, neurodegenerative diseases, cardiovascular health, and public health interventions. Collaborative projects include studies on Alzheimer’s pathology, iron metabolism, lipid peroxidation, and clinical trial innovations. Her work bridges statistical rigor with translational science, addressing critical questions in aging, chronic disease, and healthcare equity. Notably, recent articles highlight her contributions to understanding SARS-CoV-2 in cord blood, hormone therapy effects, and culturally adapted parenting interventions for Filipino families.

Education:

• PhD in Biostatistics from the University of Southern California

Research Interests:

• Advanced biostatistical methods for clinical trials
• Neurodegenerative diseases (Alzheimer’s, Parkinson’s)
• Cardiovascular epidemiology and atherosclerosis progression
• Impact of hormones on postmenopausal health
• Public health interventions targeting underserved populations

Grants & Funding: Extensive NIH funding for studies on biostatistical coordination, clinical trial design, and translational research in aging and chronic disease.

Labs/Teams: Leads biostatistics teams at SC CTSI and the Alzheimer’s Disease Research Center, collaborating with interdisciplinary groups to advance methodological and clinical goals.