معرفی
Violaine Saint-André is a Researcher at the Institut Pasteur's Bioinformatics and Biostatistics Hub, where she leads computational biology research focused on immune response determinants through the Milieu Intérieur project. She holds a PhD in Molecular Biology/Genetics from Université Paris VI and an MSc in Bioinformatics from Université Paris VII.
Her research investigates transcriptional regulatory networks, epigenetic mechanisms, and multivariate analysis of immune variability. Key interests include:
- Gene expression regulation and epigenetic memory of environmental exposures
- Determinants of human immune response heterogeneity
- Computational methods for multi-omics data integration
- Impact of smoking on long-term immune adaptation
Her publications demonstrate strong focus on immunology and computational biology, with recent work uncovering smoking's persistent epigenetic effects on immunity and cytokine regulation. Research frequently involves high-dimensional data analysis across tuberculosis, COVID-19, and HIV contexts.
She contributes significantly to academic training through courses at Institut Pasteur, Centrale-Supelec, and École Centrale de Nantes, covering ChIP-seq analysis, multivariate statistics, and health applications of AI. Actively participates in conference organization and student evaluation committees.
