Tsui-Fen Chou
استاد پژوهشی · Cellular and Developmental Biology
California Institute of Technology (Caltech)معرفی
Dr. Tsui-Fen Chou is a Research Professor of Biology and Biological Engineering at the California Institute of Technology (Caltech), where she has been affiliated since 2018. Her research bridges molecular and cellular biology with translational applications in cancer and rare diseases.
Education:
- B.S. in Biological Sciences, National Taiwan University (1999)
- Ph.D. in Biochemistry, University of Minnesota (2006)
Research Interests: Dr. Chou investigates the mechanisms of disease-causing mutations in p97/VCP ATPase, a critical regulator of cellular proteasome and autophagy pathways. She develops pathway-specific inhibitors for therapeutic targeting, focusing on cancer and rare diseases like those linked to VCP mutations. Her work integrates molecular biology, proteomics, and nanotechnology-based delivery systems.
Research Trends: Recent publications highlight her focus on proteomics (e.g., single-tissue analysis in C. elegans), viral infection mechanisms via NAMPT activity, and novel nanoformulations for pancreatic cancer. She also explores AI-driven alternatives to traditional drug screening methods.
Labs & Teams: The Chou Lab at Caltech is a multidisciplinary team advancing biomedical research through innovative approaches, including tumor microenvironment-responsive therapies and viral restriction mechanisms.
