معرفی
Tracy Brooks is the Chair and Associate Professor of Pharmaceutical Sciences at Binghamton University's School of Pharmacy and Pharmaceutical Sciences, holding the Menner Family Endowed Faculty Fellowship. She specializes in oncology and anti-cancer therapeutics, focusing on drug target development through DNA and protein interactions. Her research emphasizes G-quadruplex stabilization in oncogene promoters to regulate transcription, with applications in pancreatic, prostate, and breast cancers.
Education:
- Bachelor of Science (BS) from the University of Rochester
- Doctor of Philosophy (PhD) from the University at Buffalo (SUNY)
Research Interests: Tracy's work centers on developing novel therapies targeting oncogenes like KRAS and MYC. She explores G-quadruplex structures in promoter regions to inhibit cancer cell proliferation, leveraging small molecules and oligonucleotides. Her lab also investigates nucleic acid delivery systems and the role of epigenetic modifications (e.g., 5-hydroxymethylcytosine) in DNA structure stability.
Recent Article Trends: Her publications (2020–2025) highlight advancements in G-quadruplex ligand design, antibody-drug conjugates (ADCs), and combinatorial therapies targeting KRAS/MYC pathways. Key themes include optimizing ADC stability, validating G-quadruplex-based approaches for pancreatic cancer, and exploring transcriptional control mechanisms.
Awards:
- Inaugural Menner Family Endowed Faculty Fellow (2017)
Advising & Grants: While specific grant details are not listed, her research has consistently addressed translational oncology challenges. She advises students on projects involving molecular pharmacology and drug delivery, emphasizing cross-disciplinary approaches.
Labs & Teams: Her lab focuses on translational cancer research, collaborating with institutions like the University of Arizona and University of Mississippi on drug development and mechanistic studies.
