معرفی
Dr. Tom Hall is a Researcher at the Institute for Molecular Bioscience, University of Queensland. His work focuses on muscle development, caveolae regulation, and genetic modeling in zebrafish.
- Doctor of Philosophy, University of St Andrews
Research interests include:
- Muscle Biology: Mechanisms of muscle homeostasis, transverse tubule development, and muscular dystrophy models.
- Caveolae Dynamics: Role in mechanoprotection, oxidative stress response, and lipid regulation.
- Genomic Tools: Cre-Lox systems, proximity labeling, and large genomic deletions in zebrafish.
Recent work trends emphasize:
- Targeting the minor spliceosome for broad cancer therapy
- Mechanisms of pro-ferroptotic lipid signaling in membrane stability
- Advancements in zebrafish transgenics for disease modeling
- Structural characterization of Cavin1 complexes using nanobodies
Current funding includes:
- NHMRC IDEAS Grant (2025-2028): Scalable methodology for evaluating genetic variants of uncertain significance
- Australian Functional Genomics Network Grant (2022-2026): CAV3 variant analysis
Grants and projects:
- ARC Discovery Project (2020-2023): Molecular dissection of membrane domain formation
- NHMRC Project Grant (2016-2019): Transverse tubule development in skeletal muscle
Dr. Hall supervises PhD students as an Associate Advisor in collaboration with Professor Robert Parton and Dr. Harriet Lo. His lab specializes in:
- Membrane Biology: Caveolae structure, Cavin protein interactions
- Genetic Modeling: Zebrafish systems for muscular disorders and drug delivery
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