جست‌وجوی استاد و پژوهشگر

Rotem Karniمشاهده پروفایل

دانشیار

• Alternative RNA Splicing
• RNA Biology
• Cancer Therapy
• +۴ مورد دیگر

Rotem Karni, PhD, is an Associate Professor of Genetics at the Perelman School of Medicine, University of Pennsylvania, Philadelphia. He leads a research lab focused on understanding how alternative RNA splicing contributes to cancer and genetic diseases, with a strong emphasis on translating these findings into RNA-based therapies. Karni's lab develops decoy oligonucleotides, small molecules, and splice-switching technologies to modulate splicing factors and enhance immunotherapy. Education BSc in Biological Chemistry from The Hebrew University of Jerusalem (1997) PhD in Biological Chemistry from The Hebrew University of Jerusalem, Israel (2002) Postdoctoral Fellowship at Cold Spring Harbor Laboratory, NY (2002-2007) Karni's research explores the deregulation of alternative splicing in oncogenesis, particularly how splicing factors like RBFOX2 and S6K1 influence metastasis, DNA repair, and immune checkpoint modulation. His team investigates m6A RNA modifications for stabilizing mutant genes, with applications in Duchenne Muscular Dystrophy and pancreatic cancer. The lab's work is commercialized through biotech companies: SKIP Therapeutics, Andlit Therapeutics, and RNAble. Selected Research Trends RNA mis-splicing and neoantigen generation (2025) Splicing factor inhibition for tumor suppression (2023) Metastatic splicing signatures in pancreatic cancer (2023) Immune checkpoint splicing in cancer immunotherapy (2021) m6A modulation for mRNA stabilization (2023) Advising & Collaborations Karni has mentored numerous PhD and postdoctoral researchers, many of whom now hold leadership roles in academia, biotech, and medical institutions globally. His lab collaborates extensively on projects involving RNA innovation, including partnerships with the Institute for RNA Innovation. Contact Department of Genetics & Institute for RNA Innovation, One uCity Square, Room 4018, Philadelphia, PA 19104 Phone: 215-898-5072 Email: Rotem.Karni@Upenn.edu

Foteini Mourkiotiمشاهده پروفایل

دانشیار

• Muscle Stem Cell Biology
• Mechanobiology
• Aging
• +۷ مورد دیگر

Foteini Mourkioti is an Associate Professor at the University of Pennsylvania's Perelman School of Medicine , with a joint appointment in the Graduate Groups of Cell and Molecular Biology and Bioengineering . She co-directs the Musculoskeletal Regeneration Program at the Penn Institute of Regenerative Medicine and leads the McKay Orthopaedic Research Laboratory . Research Interests : Muscle Stem Cell Biology Mechanobiology Muscle Regeneration Telomere Biology in Muscular Diseases Fibrodysplasia Ossificans Progressiva (FOP) Cardiomyopathy and Aging Key Research Contributions : Developed the Pax7EGFP mouse model for real-time muscle stem cell tracking Discovered telomere shortening as a critical factor in Duchenne Muscular Dystrophy Elucidated the role of NF-κB in muscle stem cell dysfunction Identified Piezo1's role in stem cell morphological states Characterized fibro-adipogenic progenitor dynamics in FOP Scientific Awards : NIH/NHLBI R01 grant recipient (2019) NASA grant awardee (2020, 2017) American Heart Association grant (2017) Muscular Dystrophy Association grant (2019) University Research Foundation grant (2018) Publications & Collaborations : Over 25 publications in high-impact journals like Science Advances , Nature Protocols , and Cell Reports . Collaborates with Penn Cardiovascular Institute and Pennsylvania Muscle Institute.

• Medical Genetics
• Nephrology
• Genomics
• +۳ مورد دیگر

Dr. Ian Wilson is a researcher at Newcastle University with a focus on medical genetics, nephrology, and genomic analysis. His work spans genetic determinants of kidney diseases, mitochondrial disorders, and biomarker development. Notable contributions include studies on uromodulin genetics in African populations, copy-number variations in rare diseases, and kidney ciliopathies. He has collaborated extensively on projects involving genome sequencing, mitochondrial replacement therapy, and muscular dystrophy biomarkers. Wilson's research integrates computational tools like machine learning for predictive modeling in urolithiasis and employs advanced imaging techniques for disease progression monitoring. Key areas: Genetic epidemiology, renal genomics, mitochondrial DNA analysis Focus on translational applications: Biomarker development for kidney stones and muscular dystrophies Interdisciplinary collaborations in ophthalmology and orthopedics His publications reflect a commitment to advancing diagnostic accuracy and understanding complex genetic disorders through multi-omics approaches.

Pablo Perez-Pineraمشاهده پروفایل

دانشیار

• Neuromuscular diseases
• Neurodegenerative diseases
• Biopharmaceutical Production
• +۴ مورد دیگر

Pablo Perez-Pinera is an Associate Professor in Biomedical and Translational Sciences at the Carle Illinois College of Medicine, University of Illinois. He leads the Genome Engineering and Transcriptional Regulation Laboratory, focusing on developing gene editing technologies for treating neurodegenerative and neuromuscular diseases. His research integrates cutting-edge genome engineering tools with innovative delivery systems to address previously incurable conditions. Dr. Perez-Pinera's research interests center on developing CRISPR-based genome editing technologies for therapeutic applications. His laboratory specializes in base editing approaches for exon skipping, particularly targeting diseases like Duchenne muscular dystrophy, Huntington's disease, Parkinson's disease, Alzheimer's disease, and ALS. His team develops novel delivery systems using AAV vectors to enable precise in vivo genome editing, with a particular focus on neurological and muscular disorders. The lab's work bridges fundamental molecular biology with translational applications, aiming to move promising technologies from bench to bedside. His laboratory has made significant contributions to the field of therapeutic genome editing, particularly in developing the SPLICER platform for efficient exon skipping through simultaneous splice site editing. His publications demonstrate expertise in base editing for neurodegenerative diseases, with multiple first-author and corresponding author papers in high-impact journals. His research has been supported by several NIH grants including R01 GM131272, UL1 TR001422, R01 GM141296, among others. Dr. Perez-Pinera actively mentors a diverse team of researchers including postdoctoral fellows, graduate students, and undergraduates. His laboratory includes researchers such as Devyani Swami (Postdoctoral Fellow), Michael Gapinske, Jackson Winter, Shraddha Shirguppe, Angelo Miskalis, and others who contribute to various aspects of genome engineering research. His grant funding supports both basic research on genome editing mechanisms and translational work toward therapeutic applications. The Genome Engineering and Transcriptional Regulation Laboratory maintains state-of-the-art facilities for molecular biology, cell culture, and in vivo studies. The team collaborates extensively with clinicians and researchers across the University of Illinois campus to translate genome editing discoveries into potential therapies for patients suffering from neurodegenerative and neuromuscular conditions.

Casper Hoogenraadمشاهده پروفایل

استاد

• Molecular Neuroscience
• Neuronal Development
• Intracellular Protein Trafficking
• +۷ مورد دیگر

Prof. Casper Hoogenraad is a full professor in Molecular Neuroscience at the Department of Cell Biology, Faculty of Science, Utrecht University. His research focuses on understanding how intracellular protein trafficking underlies neuronal development and function, with particular emphasis on the microtubule cytoskeleton, synaptic cargo trafficking, and synaptic plasticity. He leads an active research group within Utrecht University's Cell Biology department and collaborates extensively with other neuroscience research groups. Education: PhD, Erasmus University Rotterdam (1996-2001) Postdoc, Massachusetts Institute of Technology (2002-2005) Hoogenraad's research spans three main themes: cytoskeleton dynamics during neurodevelopment and synaptic plasticity, motor proteins and adaptors as regulators of synaptic transport, and psychiatric and neurologic disease disorders linked to intracellular transport. His work combines genetics, biochemistry, molecular, and cellular biology methods in in vitro (neuron cultures), ex vivo (brain slices), and in vivo (mice) systems, along with advanced microscopy techniques including immunofluorescent confocal microscopy, high-resolution live cell imaging, and photo-activated localization microscopy (PALM). Analysis of Hoogenraad's recent publications reveals a strong focus on microtubule organization, neuronal polarity, and the molecular mechanisms underlying synaptic function and dysfunction. His work frequently explores how disruptions in intracellular transport contribute to neurological disorders including Alzheimer's disease, schizophrenia, and autism spectrum disorders, with particular attention to the relationship between cytoskeletal organization and cargo transport in neuronal compartments. Scientific Awards and Memberships: ZonMW-VIDI (2004) European Young Investigators (EURYI) award (2005) NWO-ALW VICI (2011) ERC Consolidator grants (2013) FENS-Kavli Network of Excellence (2014) European Molecular Biology Organization (EMBO) (2015) Young Academy of Europe (YAE) (2015) IBRO Kemali Prize (2016) Hoogenraad leads a research group studying neuronal development and function, with a particular focus on how intracellular transport mechanisms contribute to both normal brain function and neurological disorders. His laboratory employs a multidisciplinary approach combining molecular, cellular, and systems neuroscience techniques to investigate the molecular basis of neuronal polarity, synaptic plasticity, and the pathogenesis of neurological disorders. He has secured significant research funding through prestigious grants including ERC Consolidator grants. The Hoogenraad lab operates within the Cell Biology department at Utrecht University, collaborating with other research groups focusing on cellular dynamics, biophysics, and neurobiology. The lab utilizes advanced microscopy techniques including immunofluorescent confocal microscopy, high-resolution live cell imaging (spinning disc microscopy and total internal reflection fluorescence microscopy), and quantitative analysis using advanced high-resolution microscopy (photo-activated localization microscopy). Current lab technicians include Phebe Wulf and Bart de Haan.

Patrick J. Cahillمشاهده پروفایل

پزشک-پژوهشگر

• Pediatric Spine Surgery
• Scoliosis
• Minimally Invasive Spine Surgery
• +۴ مورد دیگر

Patrick J. Cahill, MD, is a pediatric spine specialist and the Robert M. Campbell Jr. Endowed Chair in Thoracic Insufficiency Syndrome at Children's Hospital of Philadelphia (CHOP). His clinical expertise spans disorders of the pediatric spine, scoliosis, cervical spine conditions, and minimally invasive surgical techniques. He leads the Center for Thoracic Insufficiency Syndrome, collaborating with pulmonology, anesthesia, and physical therapy teams. Academic Role: Physician Scientist Leadership: Director of the Center for Thoracic Insufficiency Syndrome Research Focus: Spinal growth modulation, 3D surgical planning, and reducing anesthesia exposure in young patients His work emphasizes fusionless treatments like magnetically expandable growing rods and Mehta casting, alongside innovations in dynamic MRI for preoperative assessment. Recent publications highlight comparative studies on spinal fusion techniques, surgical complication classifications, and multidisciplinary approaches to complex cases. Awards: Philadelphia Magazine's Top Doctors (2022), SRS Travelling Fellowship (2015) Professional Memberships: Scoliosis Research Society, North American Spine Society, Pediatric Orthopaedic Society of North America

Zhi-Pei Liangمشاهده پروفایل

استاد

• Magnetic Resonance Imaging
• Medical Imaging
• Biomedical Engineering
• +۵ مورد دیگر

Zhi-Pei Liang is the Franklin W. Woeltge Professor in the Department of Electrical and Computer Engineering at the University of Illinois at Urbana-Champaign, with joint appointments in the Department of Bioengineering, Beckman Institute for Advanced Science and Technology, and Coordinated Science Laboratory. His research spans biomedical engineering, medical imaging, and signal processing with a focus on advancing magnetic resonance imaging and spectroscopy technologies. His educational background includes a Ph.D. in Biomedical Engineering from Case Western Reserve University (1989) and a B.S. in Electrical Engineering from South-China University of Technology (1982), followed by postdoctoral training at UIUC (1989-1991). Professor Liang's research interests center on magnetic resonance imaging and spectroscopy , with particular emphasis on ultrafast imaging techniques , model-based reconstruction methods , and the integration of physics-based modeling with machine learning . His pioneering work on SPICE (SPectroscopic Imaging by exploiting spatiospectral CorrElation) has revolutionized high-resolution metabolic brain imaging by enabling label-free molecular imaging through the marriage of spin physics and machine learning. His research spans pattern recognition, parameter estimation, image formation theory, and algorithms for medical imaging applications. Analysis of his recent publications reveals a strong focus on high-resolution metabolic imaging , particularly using SPICE methodology to map brain metabolism with unprecedented detail. His work bridges fundamental physics of magnetic resonance with advanced computational methods to overcome traditional limitations in imaging speed and resolution. Current research directions include J-resolved spectroscopic imaging, deuterium-based metabolic mapping, and multimodal integration of PET and MRSI for studying neurological disorders. Elected to International Academy of Medical and Biological Engineering (2012) Gold Medal, International Society for Magnetic Resonance in Medicine (2022) Technical Achievement Award, IEEE Engineering in Medicine and Biology Society (2014) Fellow, National Academy of Inventors (2021) Author of influential book 'Principles of Magnetic Resonance Imaging' (1999) President of IEEE Engineering in Medicine and Biology Society (2011-2012) Professor Liang has advised numerous students and postdocs in biomedical imaging research and has received multiple teaching honors including the Ronald W. Pratt Outstanding Teaching Award (2005) and multiple listings among UIUC's Excellent Teachers. His research has been supported by various grants from NIH, NSF, and other funding agencies. He leads the SPICE (Spectroscopic Imaging by exploiting spatiospectral Correlation) research group which focuses on developing novel imaging techniques that combine physics-based modeling with machine learning for ultrafast metabolic imaging. His laboratory, part of the Beckman Institute's Integrative Imaging Theme, collaborates extensively with clinical researchers at Carle Illinois College of Medicine and other institutions to translate advanced imaging techniques into clinical applications for neurological disorders, cancer, and metabolic diseases. Current projects focus on high-resolution mapping of brain metabolism in Alzheimer's disease, stroke, and brain tumors using novel MR spectroscopic imaging techniques.

Kuo-Fen Leeمشاهده پروفایل

استاد

• Molecular Neurobiology
• Nerve Regrowth
• Spinal Cord Injury
• +۵ مورد دیگر

Kuo-Fen Lee, PhD is a Professor at the Salk Institute for Biological Studies, holding the prestigious Helen McLoraine Chair of Molecular Neurobiology. He leads the Clayton Foundation Laboratories for Peptide Biology, where his research focuses on nerve regeneration, spinal cord injury, and molecular mechanisms underlying neural development and neurodegenerative diseases. His work bridges basic neuroscience with potential therapeutic applications for conditions like ALS, paralysis, and Alzheimer's disease. Dr. Lee received his educational training from multiple prestigious institutions: a degree in Plant Pathology from National Taiwan University; an MS in Cancer Enzymology and Cell Differentiation from National Yang-Ming Medical College, Taiwan; a PhD in Endocrinology from Baylor College of Medicine, Houston; and completed his postdoctoral training at the Whitehead Institute for Biomedical Research. His primary research interests center on understanding why humans cannot regenerate damaged nerves while many other animals can. Dr. Lee has made significant discoveries regarding the p45 protein, which promotes nerve regrowth in mice but is absent in humans (who instead have p75, which inhibits nerve growth). His laboratory also studies neuregulin signaling, neuromuscular synapse formation, and the role of various proteins like nestin in neural development and maintenance. His work often employs mouse models to investigate spinal cord injury, pain pathways, and neurodegenerative conditions. Analysis of Dr. Lee's recent publications reveals a consistent focus on molecular neurobiology with particular emphasis on neural signaling pathways, synaptic maintenance, and nerve regeneration mechanisms. His research spans from basic molecular mechanisms to potential therapeutic applications, with increasing attention to pain pathways, Alzheimer's disease models, and the intersection of neuroscience with immunology and metabolism in recent years. As holder of the Helen McLoraine Chair of Molecular Neurobiology, Dr. Lee has received significant institutional recognition for his contributions to neuroscience. While specific awards aren't detailed in the provided text, his sustained funding and leadership position indicate substantial peer recognition in his field. Dr. Lee's research program involves extensive collaboration with other neuroscience laboratories, as evidenced by his numerous co-authored publications across various neuroscience subdisciplines. His work has been consistently funded, allowing for the maintenance of an active research laboratory focused on nerve regeneration and molecular neurobiology. The Clayton Foundation Laboratories for Peptide Biology serves as the primary research environment for Dr. Lee's team, where they investigate molecular mechanisms of nerve development, regeneration, and degeneration using advanced genetic, molecular, and cellular approaches. The laboratory maintains active research programs in multiple areas of neural signaling and development.

Bernard Braisمشاهده پروفایل

استاد

• Neurogenetics
• Rare Neurological Diseases
• Genetic Disorders
• +۵ مورد دیگر

Bernard Brais serves as Director of the Rare Neurological Diseases Group at the Montreal Neurological Institute-Hospital (The Neuro), which operates as a McGill University research and teaching institute and is part of the Neuroscience Mission of the McGill University Health Centre. His academic appointment at McGill University positions him within one of Canada's premier neuroscience research environments. Dr. Brais completed his MDCM, neurology residency, and PhD at McGill University, establishing his deep institutional connections. He additionally possesses specialized training as a historian of neurosciences and genetics, which informs his comprehensive approach to neurological disorders. His research program centers on the genetic basis of neurogenetic disorders with founder effects in Quebec populations, with particular emphasis on disorders exhibiting ataxic manifestations such as Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS). Since 2007, he has led a dedicated research team investigating ARSACS, building on his earlier work identifying causal genes for Oculopharyngeal muscular dystrophy (OPMD), Hereditary Sensory and Autonomic Neuropathy type II (HSANII), Limb Girdle Muscular Dystrophy with Quadriceps atrophy (LGMD2L), Pol III-related leukodystrophies, and ZAK congenital myopathy. Analysis of Dr. Brais's publication record reveals a cohesive research trajectory spanning clinical studies of disease progression, molecular genetics investigations of causal mutations, and preclinical work with animal models. His work consistently focuses on rare neurological conditions with strong genetic components, particularly those showing founder effects in Quebec populations, with substantial contributions to understanding neuromuscular disorders, ataxias, leukodystrophies, and neuropathies. As Director of the Rare Neurological Diseases research group, Dr. Brais oversees multiple research initiatives investigating various rare neurological conditions. His laboratory work integrates clinical research with basic science approaches, utilizing patient populations for clinical studies while employing cellular and animal models to elucidate disease mechanisms. His clinical work is associated with the Neuromuscular Programme at The Neuro, where he applies his research findings to patient care.

• Genetics
• Molecular Biology
• Gene Therapy
• +۴ مورد دیگر

Shushu Huang is an Associate Research Scientist in the Department of Genetics at Yale School of Medicine. They hold a PhD from Nanjing Medical University (2023) and an MD from the same institution (2013). Their research focuses on genetic and molecular mechanisms underlying metabolic disorders, muscular dystrophies, and cardiovascular diseases. Key areas include CRISPR-based therapeutic discovery, high-throughput functional genomics, and gene therapy safety. Huang has collaborated with researchers like Monkol Lek and Carlos Fernandez-Hernando on projects involving LXR signaling, DUX4 toxicity, and MC4R variant analysis. Publications span studies on vascular biology, gene therapy outcomes, and obesity genetics. Notable work includes investigating hypercholesterolemia’s role in vascular remodeling and analyzing MC4R variants in morbid obesity. Their lab is located in the Anlyan Center, New Haven.

Elliot L. Dimbergمشاهده پروفایل

استاد بالینی

• Neuromuscular Disorders
• Clinical Neurophysiology
• Peripheral Nerve Disorders
• +۴ مورد دیگر

Dr. Elliot L. Dimberg is a neurologist specializing in neuromuscular disorders at Mayo Clinic Hospital in Jacksonville, Florida. He serves as faculty at Mayo Clinic Alix School of Medicine within the Department of Neurology, holding leadership roles including Vice Chair of the Curriculum Committee and Clerkship Sub Committee. Dr. Dimberg actively contributes to medical education through multiple committees related to student promotions, academic affairs, and residency program evaluation, while maintaining a clinical practice focused on complex neuromuscular conditions. Dr. Dimberg earned his MD from Tulane University in 2001. He completed his Neurology residency and served as Chief Resident at the University of Virginia, followed by fellowships in Clinical Neurophysiology at the University of Virginia (2006) and Neuromuscular Disease at Mayo Clinic Rochester (2008). He maintains board certification in Neurology, Clinical Neurophysiology, and Neuromuscular Medicine through the American Board of Psychiatry and Neurology. His clinical expertise spans neuromuscular junction disorders including myasthenia gravis and Lambert-Eaton Myasthenic Syndrome, peripheral neuropathies, brachial and lumbosacral plexus disorders, polyradiculopathies, motor neuron diseases, and myopathies. Dr. Dimberg integrates clinical evaluation with electrodiagnostic medicine to diagnose and manage these complex conditions. His research focuses on advancing diagnostic methodologies through electromyography techniques, genetic testing, and clinical trial participation for rare neuromuscular disorders. Dr. Dimberg's publication record demonstrates consistent contributions to neuromuscular medicine, with emphasis on diagnostic precision, genetic underpinnings of muscle disorders, and therapeutic innovations. His recent work includes clinical trials for hereditary transthyretin amyloidosis, studies on spinal muscular atrophy treatments, and investigations into immune-mediated necrotizing myopathy, reflecting his commitment to advancing both clinical practice and scientific understanding in his field. Multiple Above and Beyond Awards from Mayo Clinic in Florida (2008-2024) A.B. Baker Teacher Recognition Award from American Academy of Neurology (2013, 2021) Commitment to Education Award from Mayo Clinic Alix School of Medicine (2019) Alpha Omega Alpha Honor Society membership (2000) As an educator, Dr. Dimberg has coordinated the Residency Neuroanatomy Course and Clinical Pathological Correlation Conference for over a decade. He previously chaired the Curriculum Committee for the Adult Neurology Residency Program and currently serves in leadership roles for Mayo Clinic Alix School of Medicine's educational committees. His dedication to teaching has been recognized through numerous awards including the prestigious A.B. Baker Teacher Recognition Award. Professionally, Dr. Dimberg serves as Co-Chair of the American Association of Neuromuscular and Electrodiagnostic Medicine's EDX Lab Accreditation Committee and holds leadership positions in the American Clinical Neurophysiology Society. He contributes to developing certification exams, educational programming, and clinical guidelines for these organizations, maintaining active engagement with the broader neuromuscular medicine community.

Megan Laura McCainمشاهده پروفایل

استاد

• Biomedical Engineering
• Tissue Engineering
• Regenerative Medicine
• +۴ مورد دیگر

Megan Laura McCain is a Professor of Biomedical Engineering at the University of Southern California (USC), with a secondary appointment in the Department of Stem Cell Biology and Regenerative Medicine at the Keck School of Medicine. She leads the McCain Lab, focused on developing microphysiological systems, particularly heart- and muscle-on-a-chip models, to study disease mechanisms and therapeutic responses. McCain holds affiliations with the Biomedical Engineering Society, American Society for Cell Biology, and American Heart Association. Her education includes a B.S. in Biomedical Engineering from Washington University in St. Louis (2006), a Ph.D. in Engineering and Applied Sciences from Harvard University (2012), and postdoctoral research at Harvard’s Wyss Institute. Notable awards include the American Heart Association Pre-doctoral Fellowship and Harvard’s Derek Bok Certificate of Distinction in Teaching. McCain’s research integrates tissue engineering, stem cell biology, and microfluidics to model complex biological systems. Her work emphasizes understanding how microenvironments influence cellular behavior in diseases like cardiovascular disorders and muscular dystrophy. Recent studies explore paracrine interactions in engineered tissues, sex-based proteomic differences in vascular cells, and hypoxia-induced signaling in cardiac fibroblasts. Her scientific contributions include advancements in 3D bioprinting, microfluidic platforms for disease modeling, and synthetic biology tools for cellular control. McCain’s lab collaborates widely to translate findings into clinical applications, such as personalized medicine and regenerative therapies.

• Clinical sciences
• Neurosciences
• Medical physiology
• +۲ مورد دیگر

Jinhong Meng is a Senior Research Fellow at the Department of Genetics & Genomic Medicine, University College London (UCL), focusing on neuromuscular disorders and gene therapy. He earned his PhD and Bachelor’s degrees from the Fourth Military Medical University. Education: Doctor of Philosophy, Fourth Military Medical University (2000) Bachelor, Fourth Military Medical University (1995) Research Interests: Jinhong Meng’s work centers on Duchenne Muscular Dystrophy (DMD), Spinal Muscular Atrophy (SMA), and gene therapy techniques including CRISPR, lentiviral vectors, and antisense oligonucleotides. His studies explore immune responses to dystrophin, vascular defects in SMA, and dystrophin correction via viral and non-viral delivery systems. Publication Trends: Over the past eight years, Jinhong Meng has published extensively on DMD and SMA, with a focus on gene editing, dystrophin restoration, and cellular therapies. His collaborative work spans lentiviral vectors, foamy virus transduction, and necroptosis mechanisms in muscle degeneration. Labs & Collaborations: He works within UCL’s Genetics & Genomic Medicine Department, collaborating on projects involving dystrophic muscle engraftment, circadian signaling, and RNA editing for genetic mutations.

Panying Rongمشاهده پروفایل

استادیار

• Motor Speech Disorders
• Biomechanics
• Speech Assessment
• +۳ مورد دیگر

Panying Rong, Ph.D. is an Assistant Professor in the Department of Speech-Language-Hearing: Sciences & Disorders at the University of Kansas , within the College of Liberal Arts and Sciences. Her research focuses on the neuromechanical basis of motor speech disorders and the development of quantitative tools for speech assessment. Primary Affiliation: University of Kansas Department: Speech-Language-Hearing: Sciences & Disorders Academic Rank: Assistant Professor Email: prong@ku.edu Research Interests Dr. Rong’s work investigates the biomechanical and neurological mechanisms underlying speech impairments in neurodegenerative diseases like ALS and Parkinson’s. Key areas include: Mechanistic modeling of speech motor control Development of data-driven speech diagnostics Acoustic and kinematic analysis of bulbar disorders Compensatory articulatory strategies in speech pathologies Temporal structuring of speech signals Integration of multimodal assessments for neurological conditions Article Trends Her recent publications emphasize automated, multimodal frameworks for assessing bulbar ALS, neuromechanical biomarkers, and cultural-linguistic influences on speech outcomes. Techniques include EMA, EMG, kinematic modeling, and computational analysis of speech subsystems.

• Neural control of movement
• Infant development
• Motor control
• +۵ مورد دیگر

Beth Smith, PT, DPT, PhD is an Associate Professor of Pediatrics and Biokinesiology & Physical Therapy at the University of Southern California. She directs the Infant Neuromotor Control Laboratory, where she leads research on neural control of movement during infancy and develops interventions for infants with or at risk for developmental delay. Dr. Smith's research focuses on several critical areas in pediatric development: Neural mechanisms underlying infant motor development Application of wearable sensor technology for objective movement measurement Early identification of developmental delays through quantitative analysis Evaluation of intervention effectiveness for at-risk infants Cross-cultural studies of infant development in diverse settings including rural Guatemala Her work demonstrates a strong integration of technology and clinical practice, with recent publications highlighting innovative approaches to measuring infant movement in natural environments. Dr. Smith's research on algorithmic detection of developmental disabilities using wearable sensors represents a significant advancement in early identification methods. Her studies on telehealth administration of developmental assessments have gained particular relevance following the COVID-19 pandemic, potentially expanding access to early intervention services globally. As director of the Infant Neuromotor Control Laboratory, Dr. Smith oversees a research program that bridges neuroscience, engineering, and clinical practice to improve outcomes for infants with developmental challenges. Her work has important implications for developing evidence-based interventions that can be implemented across diverse healthcare settings.