معرفی
Foteini Mourkioti is an Associate Professor at the University of Pennsylvania's Perelman School of Medicine, with a joint appointment in the Graduate Groups of Cell and Molecular Biology and Bioengineering. She co-directs the Musculoskeletal Regeneration Program at the Penn Institute of Regenerative Medicine and leads the McKay Orthopaedic Research Laboratory.
Research Interests:
- Muscle Stem Cell Biology
- Mechanobiology
- Muscle Regeneration
- Telomere Biology in Muscular Diseases
- Fibrodysplasia Ossificans Progressiva (FOP)
- Cardiomyopathy and Aging
Key Research Contributions:
- Developed the Pax7EGFP mouse model for real-time muscle stem cell tracking
- Discovered telomere shortening as a critical factor in Duchenne Muscular Dystrophy
- Elucidated the role of NF-κB in muscle stem cell dysfunction
- Identified Piezo1's role in stem cell morphological states
- Characterized fibro-adipogenic progenitor dynamics in FOP
Scientific Awards:
- NIH/NHLBI R01 grant recipient (2019)
- NASA grant awardee (2020, 2017)
- American Heart Association grant (2017)
- Muscular Dystrophy Association grant (2019)
- University Research Foundation grant (2018)
Publications & Collaborations: Over 25 publications in high-impact journals like Science Advances, Nature Protocols, and Cell Reports. Collaborates with Penn Cardiovascular Institute and Pennsylvania Muscle Institute.
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