معرفی
Timothy McGraw is a Professor in the Department of Biochemistry at Weill Cornell Medical College, with a secondary appointment in Cardiothoracic Surgery. His research bridges molecular cell biology and translational medicine, focusing on insulin-regulated glucose metabolism and cancer immunology.
He earned his undergraduate degree in Chemistry from the University of Chicago and a PhD in Microbiology from NYU. He completed postdoctoral training in the lab of Frederick Maxfield at Columbia College of Physicians and Surgeons, studying transferrin receptor trafficking. He previously served as an Assistant Professor in the Department of Pathology at Columbia before joining Weill Cornell Medicine.
His research centers on understanding how insulin controls glucose uptake via GLUT4 trafficking in fat and muscle cells, a key process disrupted in type 2 diabetes. He also investigates how lung cancer cells evade immune surveillance, particularly through PD-L1 regulation and stromal interactions. His lab uses advanced techniques including quantitative microscopy, proteomics, and human tissue analysis.
His recent publications reveal trends in membrane trafficking, metabolic regulation, and tumor immunology, with studies spanning from molecular mechanisms to clinical correlations in lung cancer. His work frequently appears in high-impact journals such as Cell, Nature, and PNAS.
Dr. McGraw has received recognition through numerous peer-reviewed publications and collaborative research, though specific awards are not listed in the provided text.
He mentors students and researchers in his lab, contributing to training in biochemistry and medical sciences. His work includes collaborations with clinicians such as Nasser Altorki, emphasizing translational impact. He leads projects on insulin signaling, GIP receptor biology, and immune evasion in early lung cancer.
His lab, the McGraw Lab, is actively involved in studying cellular trafficking pathways, metabolic disease mechanisms, and tumor microenvironment dynamics, maintaining a strong focus on both basic science and therapeutic applications.
