معرفی
Professor Tibor Kristian is a faculty member in the Department of Anesthesiology at the University of Maryland Baltimore. His research focuses on mitochondrial dysfunction and NAD+ catabolism in acute brain injury and chronic neurodegenerative diseases, utilizing transgenic animal models to investigate neuroprotective mechanisms.
- Education: M.S. from Safarik's University, Slovakia; Ph.D. from Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences; Post-doctoral studies at Lund University Hospital, Sweden; Senior Research Scientist at The Queens Medical Center, Hawaii.
Research interests include:
- Neurodegeneration
- Mitochondrial Dynamics
- Bioenergetics
- NAD+ Salvage Pathway
Recent publications highlight studies on ischemic brain injury, mitochondrial fragmentation, and therapeutic interventions targeting NAD+ metabolism. His lab develops transgenic models expressing mitochondria-targeted fluorescent proteins for cell-type specific analysis.
Scientific honors include a VA Merit Review Award for "Nudix hydrolases and mitochondrial dynamics in acute neurodegenerative disease."
Current research examines:
- Enzymes regulating NAD+ degradation
- Molecular mechanisms of ischemic injury
- Metabolite effects post-NAD+ catabolism
- Mitochondrial dynamics in neurodegeneration
