Tiago Fleming Outeiro

Prof. Tiago Fleming Outeiro is a Full Professor and Director of the Department of Experimental Neurodegeneration at the University Medical Center Göttingen, Germany, with auxiliary professorship at the University of Lisbon's Faculty of Medicine. His academic journey includes postdoctoral training at Harvard University and leadership roles in Portugal's Instituto de Medicina Molecular. He holds a PhD from MIT's Whitehead Institute and a BS from the University of Porto.

His research focuses on understanding protein misfolding/aggregation mechanisms in neurodegenerative diseases like Parkinson's and Alzheimer's, employing model organisms from yeast to mice. Innovations include developing multi-photon microscopy for in vivo brain imaging and translating findings into therapeutic approaches. Major projects include the MBExC Cluster (multiscale bioimaging) and SFB 1286 (quantitative synaptology).

Research trends emphasize alpha-synuclein's role in synucleinopathies, cross-disease mechanisms (e.g., diabetes-Parkinson's links), and AI-driven protein structure analysis. Collaborations with clinicians accelerate drug discovery and clinical applications.

No scientific awards are explicitly listed. His advisory/leadership roles include directing a 20+ member lab and overseeing interdisciplinary research projects. The Department of Experimental Neurodegeneration actively engages in translational research through academic partnerships.

Laboratory work centers at the University Medical Center Göttingen with affiliations to Neuroscience and Molecular Medicine programs. Ongoing projects integrate advanced imaging, proteomics, and computational biology to address unmet therapeutic needs in neurodegeneration.