Thorsten Mielke

Dr. Thorsten Mielke is the Head of the Microscopy & Cryo-Electron Microscopy Service Group at the Max Planck Institute for Molecular Genetics in Berlin, Germany. His role involves supporting researchers and students across the institute with advanced imaging techniques, including light microscopy (LM) and transmission electron microscopy (TEM), while focusing on method development and automation for biological imaging.

• Operates state-of-the-art microscopes: confocal, Airyscan super-resolution, FLIM-STED, light sheet, and 300 kV cryo-TEM with direct electron detectors.
• Specializes in correlative microscopy, cryo-expansion techniques, and smart microscopy workflows.
• Collaborates with research groups like Aydan Bulut-Karslıoğlu's team for ultrastructural analysis.

His group bridges LM and TEM/SEM, enabling live-cell imaging followed by high-resolution structural analysis. He emphasizes data analysis tools for quantifying biological structures (e.g., nuclei, mitochondria) in complex datasets.