Thomas Mavromoustakos

Professor Thomas Mavromoustakos holds the position of Professor of Organic Chemistry at the Department of Chemistry of the National and Kapodistrian University of Athens. His research focuses on drug design, medicinal chemistry, and molecular modeling, with a strong emphasis on anti-inflammatory agents, antiviral drugs, and hypertension therapeutics. He leads studies on bioactive compounds using advanced spectroscopic techniques (NMR, Raman), computational methods (DFT, MD simulations), and drug delivery systems involving cyclodextrins and nanoparticles.

Key research areas include the development of angiotensin receptor blockers (ARBs) for hypertension and their repurposing against SARS-CoV-2, the design of novel MAO-B inhibitors for neurodegenerative diseases, and the exploration of peptide-based vaccines for autoimmune disorders like multiple sclerosis. His work integrates organic synthesis with computational biology to target complex biological systems, such as gut bacteria-host interactions and viral protease inhibition.

Professor Mavromoustakos collaborates extensively on nanomedicine applications, including drug-loaded polymers and silver nanoparticle-embedded hydrogels for medical devices. His contributions span from fundamental mechanistic studies to translational drug development, with a focus on bridging chemistry and clinical sciences.