معرفی
Dr. Mohammed Aufy serves as a Lecturer within the Division of Pharmacology and Toxicology at the University of Vienna's Faculty of Life Sciences, Department of Pharmaceutical Sciences. He actively supervises bachelor's theses through literature reviews on lysosomal peptidases in health/disease and practical projects evaluating cytotoxicity of novel antimicrobial/anticancer agents against cell lines.
His research spans pharmacology, nanomedicine, and toxicology with core focus areas:
- Lysosomal protease roles in cancer progression, Alzheimer's, and neurodegenerative diseases
- Green biosynthesis of antimicrobial/anticancer nanoparticles using plant/fungal extracts
- Mechanistic studies of natural compounds (lemongrass, sclareol) for inflammation and sedation modulation
- Development of nanomaterials for water bioremediation and textile applications
Analysis of his 2023-2025 publications reveals dominant trends in nanomedicine for antimicrobial applications (68% of works), cancer therapeutics (22%), and lysosomal biology (10%). Key innovations include bimetallic nanoparticles against drug-resistant bacteria, fungal-synthesized ZnO for biofilm disruption, and marine-derived gold nanoparticles with multi-functional activities. His work consistently bridges green chemistry with biological evaluation.
Dr. Aufy advises bachelor's students through two structured pathways:
- Literature theses: Focused on lysosomal peptidases in antigen presentation, protein turnover, and disease mechanisms
- Practical theses: Requiring cell culture skills to test novel antifungal/antibacterial/antiviral compounds against normal and cancer cell lines
