Thomas G. Blanchard

Dr. Thomas G. Blanchard is a Professor in the Department of Pediatrics at the University of Maryland School of Medicine. He serves as the Director of the University of Maryland Brain and Tissue Bank (UMBTB) and has held this position since 2007. His academic journey includes a PhD in Immunology from the University of Massachusetts (1991) and a JD from Case Western Reserve University (2002).

Education:

• University of Massachusetts, B.S., Biology, 1985
• University of Massachusetts, Ph.D., Immunology, 1985-1991
• Case Western Reserve University, J.D., 2002

Dr. Blanchard specializes in immunology, particularly mucosal immunology, focusing on the host response to Helicobacter pylori (H. pylori) infections. His work has elucidated mechanisms of immune evasion by H. pylori and pioneered vaccine development strategies, including neonatal vaccination and systemic/mucosal delivery. Notably, he has demonstrated the roles of IL-10, Treg cells, dendritic cells, and Th17/Th1 responses in immunity.

Recent research explores andrographolide (AGP) in colon cancer therapy, revealing its capacity to induce ER stress, upregulate tumor suppressor genes (PTEN, RASSF1A), and trigger apoptosis. His publications span topics like H. pylori genomics, IRAK-M signaling, and lymphoid follicle formation, reflecting interdisciplinary expertise in immunology, microbiology, and oncology.

Leadership Roles:

• Director, University of Maryland Brain and Tissue Bank (2007–present)