معرفی
Talitha T. Rajah serves as an Associate Professor of Cancer Biology in the Department of Biological Sciences at DePaul University's College of Science and Health. She teaches core undergraduate courses including Cancer Biology (Bio 380/480), Genetic Toxicology with Lab (Bio 355/455), Cell Biology with Lab (Bio 250), Senior Capstone (Bio 395), and Topics in Cancer (Bio 390) across multiple academic quarters.
Her educational background includes a PhD in Biological Sciences, establishing her expertise in molecular cancer mechanisms. Research interests focus on phytoestrogen interactions with breast cancer pathways, specifically examining genistein's effects on cell proliferation, apoptosis, migration, and invasion through estrogen receptor signaling modulation.
Analysis of her 2009-2012 publications reveals consistent investigation into genistein's concentration-dependent anti-cancer mechanisms. Key patterns include its synergistic effects with estradiol, regulation of Bax/Bcl-2 apoptotic ratios, and inhibition of proliferation via pERK1/2 and p90RSK pathways in both ER-positive (T47D) and triple-negative (MDA-MB-231) breast cancer models.
