Susanne Mandrup

Susanne Mandrup is Professor at the Department of Biochemistry and Molecular Biology at the University of Southern Denmark where she serves as Director of the Center of Excellence in Functional Genomics and Tissue Plasticity (ATLAS) and Center for Adipocyte Signaling (ADIPOSIGN), Head of the Functional Genomics & Metabolism Research Unit, and Chair of Biochemistry and Molecular Biology at the Danish Institute of Advanced Study (DIAS).

Prof. Mandrup earned her PhD in Biochemistry in 1992 from the University of Southern Denmark (formerly Odense University) and completed postdoctoral training with Prof. M. Daniel Lane at Johns Hopkins University (1995-1996). She joined Odense University as Assistant Professor in 1996 and was promoted to full Professor in 2008.

Her research focuses on transcriptional networks regulating cellular differentiation and function, particularly the molecular cross-talk between transcriptional regulation and metabolism in fat cells and pancreatic beta cells. The Mandrup Group combines sequencing-based functional-genomics approaches with detailed molecular analyses to study adipose tissue plasticity, endocrine pancreas function, and transcriptional enhancer mechanisms in mouse models, human biopsies, and cell cultures. Recent work emphasizes single-cell resolution studies of adipose tissue and enhancer dynamics in metabolic disease.

Prof. Mandrup's publication record demonstrates consistent leadership in adipose tissue biology, with recent articles spanning proteome profiling of liver disease, single-cell dynamics during weight loss, and consensus atlases of adipose tissue. Her work integrates genomics, transcriptomics, and proteomics to understand tissue plasticity in obesity, metabolic dysfunction, and transcriptional regulation.

• Villum Kann Rasmussen Annual Award (2023)
• Else Marie Lønggaard Travel Grant (2007)
• Knight of the Order of Dannebrog
• Member of the Royal Danish Academy of Sciences and Letters
• Member of Academia Europaea
• Member of AcademiaNet
• Member of EMBO
• Carlsberg Foundation Board of Directors

Prof. Mandrup has supervised 18 PhD students and leads major research initiatives including the Villum Kann Rasmussen Annual Award project (2024-2034), ATLAS 2.0 Center of Excellence (2024-2027), and Novo Nordisk Foundation research on β-cell maturation (2023-2025). She regularly organizes significant scientific events including the ATLAS Annual Meeting and specialized workshops on tissue plasticity.

The Mandrup Group operates within SDU's Department of Biochemistry and Molecular Biology as part of the Functional Genomics & Metabolism Research Unit. They maintain extensive national and international collaborations through centers like ATLAS and ADIPOSIGN, contributing significantly to understanding obesity, metabolic syndrome, and related disorders at the molecular level.